Two Sigma Securities’s Definium Therapeutics DFTX Stock Holding History

Two Sigma Securities’s Portfolio DFTX Stock Details DFTX Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	$315K	Buy	+6,704	New	+$166K	0.03%	837
2023 Q1	–	Sell	-24,099	Closed	-$53K	–	3043
2022 Q4	$53K	Buy	+24,099	New	+$66.9K	﹤0.01%	2152
2022 Q3	–	Sell	-709	Closed	-$7K	–	2908
2022 Q2	$7K	Sell	709 -542	-43%	-$6.86K	﹤0.01%	2089
2022 Q1	$21K	Sell	1,251 -1,172	-48%	-$20.3K	﹤0.01%	1972
2021 Q4	$50K	Buy	+2,423	New	+$77.3K	﹤0.01%	1276

Other funds holding DFTX

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

ACA

Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return

DCM

Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return

Jupiter Topco New York $245B AUM

Capital World Investors Los Angeles, California $846B AUM 46.74% 1-Year Est. Return

Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return

T. Rowe Price Associates Baltimore, Maryland $999B AUM 46.22% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return

State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return

Capital International Investors Los Angeles, California $484B AUM 34.9% 1-Year Est. Return

Two Sigma Securities's DFTX Position: Q2 2026 in Review

Two Sigma Securities opened a new position in Definium Therapeutics (DFTX) in Q2 2026: 6,704 shares worth $315K. The stake represents 0.03% of the portfolio and ranks #837 among its holdings. This is a return to the name: Two Sigma Securities previously reported a position in DFTX as recently as Q4 2022.

Two Sigma Securities first reported a position in DFTX in Q4 2021 and has held it in 5 quarters since. 361 funds tracked by Wall St. Rank hold DFTX as of Q2 2026.

Two Sigma Securities held 6,704 shares of Definium Therapeutics worth $315K as of Q2 2026.
Definium Therapeutics was a new Two Sigma Securities position in Q2 2026.
Definium Therapeutics made up 0.03% of Two Sigma Securities's portfolio in Q2 2026, its #837 holding.
Two Sigma Securities first reported a position in Definium Therapeutics in Q4 2021 and has held it in 5 quarters since.
361 funds tracked by Wall St. Rank held Definium Therapeutics as of Q2 2026.

Based on Two Sigma Securities's 13F filing for Q2 2026, filed 14 Aug 2026.