Two Sigma Securities’s Annovis Bio ANVS Stock Holding History

Two Sigma Securities’s Portfolio ANVS Stock Details ANVS Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2025 Q4	–	Sell	-10,511	Closed	-$21.8K	–	1452
2025 Q3	$21.8K	Buy	+10,511	New	+$26.3K	﹤0.01%	1124
2024 Q1	–	Sell	-12,282	Closed	-$230K	–	2936
2023 Q4	$230K	Buy	+12,282	New	+$109K	﹤0.01%	2271

Other funds holding ANVS

Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return

Marshall Wace London, United Kingdom $100B AUM 35.1% 1-Year Est. Return

Two Sigma Investments New York $124B AUM 33.93% 1-Year Est. Return

Susquehanna International Group Bala Cynwyd, Pennsylvania $893B AUM 36.07% 1-Year Est. Return

Jane Street New York $777B AUM 61.18% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

DADC

D.A. Davidson & Co Great Falls, Montana $16.5B AUM 19.94% 1-Year Est. Return

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

Northern Trust Chicago, Illinois $757B AUM 28.64% 1-Year Est. Return

MFG

Merit Financial Group Alpharetta, Georgia $16.4B AUM 25.17% 1-Year Est. Return

Two Sigma Securities's ANVS Position: Q4 2025 in Review

Two Sigma Securities sold out of Annovis Bio (ANVS) in Q4 2025, closing a stake of 10,511 shares — an estimated $21.8K sold.

Two Sigma Securities first reported a position in ANVS in Q4 2023 and held it in 2 quarters. The position peaked at $230K in Q4 2023. 53 funds tracked by Wall St. Rank hold ANVS as of Q4 2025.

Two Sigma Securities reported no remaining Annovis Bio position as of Q4 2025 after selling out during the quarter.
Two Sigma Securities sold 10,511 Annovis Bio shares in Q4 2025, an estimated $21.8K.
Two Sigma Securities first reported a position in Annovis Bio in Q4 2023 and held it in 2 quarters.
Two Sigma Securities's Annovis Bio position peaked at $230K in Q4 2023.
53 funds tracked by Wall St. Rank held Annovis Bio as of Q4 2025.

Based on Two Sigma Securities's 13F filing for Q4 2025, filed 17 Feb 2026.