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Two Sigma Investments

Two Sigma Investments Portfolio holdings

AUM $124B
1-Year Est. Return 33.93%
This Fund
S&P 500
This Quarter Est. Return
+3.47%
1 Year Est. Return
+33.93%
3 Year Est. Return
+96.56%
5 Year Est. Return
+105.93%
10 Year Est. Return
+538.88%
AUM
$70.9B
AUM Growth
+$3.72B
Cap. Flow
+$541M
Cap. Flow %
0.76%
Top 10 Hldgs %
4.9%
Holding
4,545
New
899
Increased
1,598
Reduced
1,287
Closed
504

Sector Composition

Rank Sector Weight
1 Technology 15.53%
2 Financials 13%
3 Industrials 11.22%
4 Healthcare 10.29%
5 Consumer Discretionary 9.15%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
MEGL icon
3901
Magic Empire Global Ltd
MEGL
$6.08M
$20.9K ﹤0.01%
+17,771
New +$24.2K
CASI
3902
DELISTED
CASI Pharmaceuticals
CASI
$20.2K ﹤0.01%
23,787
-9,480
-28% -$12.3K
CURX
3903
Curanex Pharmaceuticals
CURX
$5.53M
$20.2K ﹤0.01%
+61,102
New +$33.6K
IBO
3904
Impact BioMedical
IBO
$46.9M
$20.1K ﹤0.01%
39,827
+8,327
+26% +$4.41K
AMBR
3905
Amber International Holding Ltd
AMBR
$130M
$19.9K ﹤0.01%
11,502
-1,111
-9% -$2.19K
MYPS icon
3906
PLAYSTUDIOS Inc
MYPS
$90.1M
$19K ﹤0.01%
29,101
-123,965
-81% -$96.5K
MDCX
3907
Medicus Pharma
MDCX
$17M
$18.8K ﹤0.01%
+12,319
New +$26.4K
BIOX icon
3908
Bioceres Crop Solutions
BIOX
$22M
$18.6K ﹤0.01%
+14,182
New +$22.7K
APM
3909
DELISTED
Aptorum Group
APM
$18.5K ﹤0.01%
+17,411
New +$25.6K
PWCM
3910
PowerCompute, Inc. Common Stock
PWCM
$1.38M
$17.9K ﹤0.01%
1,612
-1,887
-54% -$45.1K
WSTNR
3911
Westin Acquisition Corp Right
WSTNR
$16.3K ﹤0.01%
+90,625
New +$16.3K
NAMM
3912
Namib Minerals
NAMM
$73.6M
$16.2K ﹤0.01%
+16,051
New +$29.6K
BBLG
3913
Bone Biologics
BBLG
$1.69M
$16.1K ﹤0.01%
+11,083
New +$22.1K
EDUC icon
3914
Educational Development Corp
EDUC
$11.8M
$15.9K ﹤0.01%
+12,052
New +$16.5K
JOB icon
3915
GEE Group
JOB
$22.5M
$15.7K ﹤0.01%
80,700
-39,826
-33% -$7.74K
PHIO icon
3916
Phio Pharmaceuticals
PHIO
$12.1M
$15.2K ﹤0.01%
+14,494
New +$23.2K
FEMY icon
3917
Femasys
FEMY
$8.03M
$15.1K ﹤0.01%
+1,307
New +$19.8K
KALA icon
3918
KALA BIO
KALA
$14.5M
$15K ﹤0.01%
+538
New +$24.1K
TRIB
3919
Trinity Biotech
TRIB
$8.39M
$14.8K ﹤0.01%
622
-178
-22% -$5.25K
CNEY icon
3920
CN Energy Group
CNEY
$5.52M
$14.6K ﹤0.01%
+23,833
New +$35.5K
BCDA icon
3921
BioCardia
BCDA
$14.6M
$14K ﹤0.01%
+11,229
New +$15.3K
ATOS icon
3922
Atossa Therapeutics
ATOS
$23.5M
$13.8K ﹤0.01%
+1,563
New +$19.8K
HKPD
3923
Cellyan Biotechnology
HKPD
$9.87M
$13.8K ﹤0.01%
+16,751
New +$18K
HUDI icon
3924
Huadi International Group
HUDI
$10.3M
$13.7K ﹤0.01%
+12,205
New +$15.8K
UAVS icon
3925
AgEagle Aerial Systems
UAVS
$53.9M
$13.3K ﹤0.01%
16,400
-4,489
-21% -$6.99K

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Two Sigma Investments's Q4 2025 Portfolio in Review

As of Q4 2025, Two Sigma Investments held 4,545 positions worth $70.9B, up 5.5% from $67.2B the previous quarter. Its ten largest holdings account for 4.9% of the portfolio.

Two Sigma Investments's Q4 2025 filing shows 899 new, 1,598 increased, 1,287 reduced and 504 closed positions. Its largest new stake was Vanguard Real Estate ETF: 3,573,400 shares worth $316M. The largest sale was State Street Financial Select Sector SPDR ETF, an estimated $547M.

By sector, the portfolio is most concentrated in Technology at 16% of assets, down from 16% a quarter earlier, followed by Financials and Industrials.

  • Two Sigma Investments's largest Q4 2025 buy was Vanguard Real Estate ETF: 3,573,400 shares worth $316M.
  • Two Sigma Investments added most to State Street Technology Select Sector SPDR ETF in Q4 2025, an estimated $395M increase.
  • Two Sigma Investments's biggest Q4 2025 reduction was State Street Financial Select Sector SPDR ETF, cutting an estimated $547M.
  • Two Sigma Investments fully exited State Street SPDR Dow Jones Industrial Average ETF Trust in Q4 2025, selling an estimated $240M.
  • Two Sigma Investments's ten largest holdings make up 4.9% of its $70.9B portfolio in Q4 2025.
  • Two Sigma Investments opened 899 new positions and closed 504 in Q4 2025.
  • Two Sigma Investments's portfolio value rose 5.5% quarter-over-quarter to $70.9B.

Based on Two Sigma Investments's 13F filing for Q4 2025, filed 17 Feb 2026.