Two Sigma Investments
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Two Sigma Investments’s KALA BIO KALA Stock Holding History

Two Sigma Investments’s Portfolio KALA Stock Details KALA Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		– Sell
-538
Closed -$15K – 4762
2025
Q4 		$15K Buy
+538
New +$24.1K ﹤0.01% 4013
2025
Q1 		– Sell
-238
Closed -$82.4K – 3354
2024
Q4 		$82.4K Sell
238
-42
-15% -$13.2K ﹤0.01% 2992
2024
Q3 		$79.8K Buy
+280
New +$88.3K ﹤0.01% 2920
2022
Q4 		– Sell
-21
Closed -$11K – 2937
2022
Q3 		$11K Buy
21
+4
+24% +$3.14K ﹤0.01% 2413
2022
Q2 		$12K Buy
+17
New +$26.7K ﹤0.01% 2428
2021
Q2 		– Sell
-69
Closed -$1.16M – 4312
2021
Q1 		$1.16M Sell
69
-118
-63% -$2.3M ﹤0.01% 2178
2020
Q4 		$3.17M Buy
+187
New +$3.52M 0.01% 1203
2020
Q3 		– Sell
-68
Closed -$1.77M – 3317
2020
Q2 		$1.77M Buy
68
+59
+656% +$1.67M 0.01% 1163
2020
Q1 		$204K Buy
+9
New +$144K ﹤0.01% 2642
2019
Q1 		– Sell
-23
Closed -$283K – 3259
2018
Q4 		$283K Buy
23
+19
+475% +$329K ﹤0.01% 2492
2018
Q3 		$107K Buy
+4
New +$122K ﹤0.01% 3071

Other funds holding KALA

Renaissance Technologies
Renaissance Technologies New York $63.9B AUM 45.56% 1-Year Est. Return
Citadel Advisors
Citadel Advisors Miami, Florida $618B AUM 30.34% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
VF
Virtu Financial New York $2.41B AUM 48.35% 1-Year Est. Return
ACM
ADAR1 Capital Management Austin, Texas $1.7B AUM 340.85% 1-Year Est. Return
GCP
GSA Capital Partners London, United Kingdom $1.61B AUM 28.28% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Jane Street
Jane Street New York $777B AUM 61.18% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.56T AUM 27.86% 1-Year Est. Return

Two Sigma Investments's KALA Position: Q1 2026 in Review

Two Sigma Investments sold out of KALA BIO (KALA) in Q1 2026, closing a stake of 538 shares — an estimated $15K sold.

Two Sigma Investments first reported a position in KALA in Q3 2018 and held it in 11 quarters. The position peaked at $3.17M in Q4 2020. 28 funds tracked by Wall St. Rank hold KALA as of Q1 2026.

  • Two Sigma Investments reported no remaining KALA BIO position as of Q1 2026 after selling out during the quarter.
  • Two Sigma Investments sold 538 KALA BIO shares in Q1 2026, an estimated $15K.
  • Two Sigma Investments first reported a position in KALA BIO in Q3 2018 and held it in 11 quarters.
  • Two Sigma Investments's KALA BIO position peaked at $3.17M in Q4 2020.
  • 28 funds tracked by Wall St. Rank held KALA BIO as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.