Two Sigma Investments
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Two Sigma Investments’s Nuvation Bio NUVB Stock Holding History

Two Sigma Investments’s Portfolio NUVB Stock Details NUVB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$7.09M Sell
1,248,409
-1,435,680
-53% -$7.02M 0.01% 1820
2026
Q1 		$11.5M Buy
2,684,089
+1,948,144
+265% +$10.9M 0.01% 1315
2025
Q4 		$6.59M Sell
735,945
-1,641,625
-69% -$10.2M 0.01% 1455
2025
Q3 		$8.8M Buy
2,377,570
+1,162,837
+96% +$3.17M 0.01% 1032
2025
Q2 		$2.37M Buy
1,214,733
+527,355
+77% +$1.1M ﹤0.01% 1713
2025
Q1 		$1.21M Sell
687,378
-463,878
-40% -$1.06M ﹤0.01% 2066
2024
Q4 		$3.06M Buy
1,151,256
+5,925
+0.5% +$15.3K 0.01% 1422
2024
Q3 		$2.62M Buy
1,145,331
+75,530
+7% +$230K 0.01% 1506
2024
Q2 		$3.12M Sell
1,069,801
-84,256
-7% -$257K 0.01% 1256
2024
Q1 		$4.2M Sell
1,154,057
-358,312
-24% -$688K 0.01% 1066
2023
Q4 		$2.28M Buy
1,512,369
+890,110
+143% +$1.15M 0.01% 1427
2023
Q3 		$834K Buy
622,259
+53,576
+9% +$89.2K ﹤0.01% 2037
2023
Q2 		$1.02M Buy
568,683
+116,628
+26% +$198K ﹤0.01% 1932
2023
Q1 		$750K Sell
452,055
-239,820
-35% -$486K ﹤0.01% 2019
2022
Q4 		$1.33M Buy
691,875
+160,892
+30% +$326K ﹤0.01% 1556
2022
Q3 		$1.19M Buy
530,983
+180,189
+51% +$514K ﹤0.01% 1387
2022
Q2 		$1.14M Buy
350,794
+250,455
+250% +$1.09M ﹤0.01% 1488
2022
Q1 		$528K Buy
+100,339
New +$564K ﹤0.01% 1995

Other funds holding NUVB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $732M AUM 275.56% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
OFM
Omega Fund Management Boston, Massachusetts $186M AUM 155.23% 1-Year Est. Return
LCM
Laurion Capital Management New York $3.9B AUM 75.03% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return
DFO
Duquesne Family Office New York $5.21B AUM 87.01% 1-Year Est. Return
American Century Companies
American Century Companies Kansas City, Missouri $226B AUM 44.75% 1-Year Est. Return

Two Sigma Investments's NUVB Position: Q2 2026 in Review

Two Sigma Investments reduced its Nuvation Bio (NUVB) stake by 53% in Q2 2026, selling an estimated $7.02M and leaving 1,248,409 shares worth $7.09M. The position accounts for 0.01% of the portfolio, ranked #1820.

Two Sigma Investments first reported a position in NUVB in Q1 2022 and has held it in 18 quarters since. The position peaked at $11.5M in Q1 2026. 244 funds tracked by Wall St. Rank hold NUVB as of Q2 2026.

  • Two Sigma Investments held 1,248,409 shares of Nuvation Bio worth $7.09M as of Q2 2026.
  • Two Sigma Investments sold 1,435,680 Nuvation Bio shares in Q2 2026, an estimated $7.02M.
  • Nuvation Bio made up 0.01% of Two Sigma Investments's portfolio in Q2 2026, its #1820 holding.
  • Two Sigma Investments first reported a position in Nuvation Bio in Q1 2022 and has held it in 18 quarters since.
  • Two Sigma Investments's Nuvation Bio position peaked at $11.5M in Q1 2026.
  • 244 funds tracked by Wall St. Rank held Nuvation Bio as of Q2 2026.

Based on Two Sigma Investments's 13F filing for Q2 2026, filed 14 Aug 2026.