Nuvation Bio
NUVB
223 hedge funds and large institutions have $1.89B invested in Nuvation Bio in 2025 Q4 according to their latest regulatory filings, with 56 funds opening new positions, 71 increasing their positions, 70 reducing their positions, and 34 closing their positions.
250% more call options, than puts
Call options by funds: $36.6M | Put options by funds: $10.5M
131% more capital invested
Capital invested by funds: $818M → $1.89B (+$1.07B)
65% more first-time investments, than exits
New positions opened: 56 | Existing positions closed: 34
50% more funds holding in top 10
Funds holding in top 10: 6 → 9 (+3)
10% more funds holding
Funds holding: 203 → 223 (+20)
1% more repeat investments, than reductions
Existing positions increased: 71 | Existing positions reduced: 70
2.81% less ownership
Funds ownership: 64.43% → 61.63% (-2.8%)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Bank of America
Charlotte,
North Carolina
|
+$19.7M |
| 2 |
T. Rowe Price Associates
Baltimore,
Maryland
|
+$15M |
| 3 |
CFM
Capricorn Fund Managers
London,
United Kingdom
|
+$9.84M |
| 4 |
Qube Research & Technologies (QRT)
London,
United Kingdom
|
+$7.93M |
| 5 |
Marshall Wace
London,
United Kingdom
|
+$6.34M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Millennium Management
New York
|
-$25.6M |
| 2 |
Citadel Advisors
Miami,
Florida
|
-$13.4M |
| 3 |
LCM
Laurion Capital Management
New York
|
-$11.5M |
| 4 |
Jane Street
New York
|
-$11.1M |
| 5 |
ACM
Aisling Capital Management
New York
|
-$11M |
NUVB Hedge Fund Activity: Q4 2025 in Review
223 of the 8,267 institutional investors tracked by Wall St. Rank reported a position in Nuvation Bio (NUVB) for Q4 2025, worth a combined $1.89B — up 131% from $818M a quarter earlier.
Buyers outnumbered sellers: 56 funds opened new NUVB positions and 34 closed out — a net gain of 22 holders — while 71 added to existing stakes and 70 trimmed.
The largest buyer was Bank of America, adding an estimated $19.7M. The largest seller was Millennium Management, cutting an estimated $25.6M.
- 223 institutional investors held Nuvation Bio (NUVB) as of Q4 2025, up from 203 in Q3 2025.
- Funds reported $1.89B of Nuvation Bio stock for Q4 2025, up 131% quarter-over-quarter.
- 56 funds opened new Nuvation Bio positions in Q4 2025 and 34 closed out, a net change of +22 holders.
- The largest Nuvation Bio buyer in Q4 2025 was Bank of America, an estimated $19.7M added.
- The largest Nuvation Bio seller in Q4 2025 was Millennium Management, an estimated $25.6M sold.
Based on aggregated 13F filings for Q4 2025.