Two Sigma Investments
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Two Sigma Investments’s Eli Lilly LLY Stock Holding History

Two Sigma Investments’s Portfolio LLY Stock Details LLY Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$3.4M Buy
3,700
+700
+23% +$710K ﹤0.01% 2334
2025
Q4 		$3.22M Buy
3,000
+1,000
+50% +$956K ﹤0.01% 2089
2025
Q3 		$1.53M Buy
+2,000
New +$1.49M ﹤0.01% 2311
2022
Q1 		– Sell
-10,400
Closed -$2.87M – 3578
2021
Q4 		$2.87M Buy
10,400
+6,300
+154% +$1.6M 0.01% 1605
2021
Q3 		$947K Sell
4,100
-6,200
-60% -$1.53M ﹤0.01% 2663
2021
Q2 		$2.36M Buy
10,300
+6,100
+145% +$1.23M 0.01% 1734
2021
Q1 		$785K Sell
4,200
-3,000
-42% -$587K ﹤0.01% 2533
2020
Q4 		$1.22M Buy
+7,200
New +$1.08M ﹤0.01% 1851
2020
Q3 		– Sell
-2,000
Closed -$328K – 3347
2020
Q2 		$328K Sell
2,000
-2,500
-56% -$384K ﹤0.01% 2315
2020
Q1 		$624K Sell
4,500
-9,100
-67% -$1.25M 0.01% 1770
2019
Q4 		$1.79M Sell
13,600
-7,500
-36% -$869K 0.01% 1680
2019
Q3 		$2.36M Sell
21,100
-56,500
-73% -$6.29M 0.01% 1300
2019
Q2 		$8.6M Buy
77,600
+17,600
+29% +$2.07M 0.03% 660
2019
Q1 		$7.79M Buy
60,000
+51,600
+614% +$6.27M 0.03% 769
2018
Q4 		$972K Sell
8,400
-23,000
-73% -$2.57M ﹤0.01% 1673
2018
Q3 		$3.37M Sell
31,400
-72,200
-70% -$7.22M 0.01% 1142
2018
Q2 		$8.84M Buy
103,600
+56,100
+118% +$4.61M 0.03% 718
2018
Q1 		$3.67M Buy
47,500
+37,200
+361% +$2.99M 0.01% 1132
2017
Q4 		$870K Sell
10,300
-28,200
-73% -$2.4M ﹤0.01% 2058
2017
Q3 		$3.29M Buy
+38,500
New +$3.16M 0.01% 1020
2017
Q1 		– Sell
-261,600
Closed -$19.2M – 3129
2016
Q4 		$19.2M Buy
261,600
+95,400
+57% +$7.1M 0.07% 323
2016
Q3 		$13.3M Buy
166,200
+113,200
+214% +$9.06M 0.05% 439
2016
Q2 		$4.17M Buy
53,000
+49,000
+1,225% +$3.69M 0.02% 846
2016
Q1 		$288K Buy
4,000
+1,000
+33% +$75.7K ﹤0.01% 2404
2015
Q4 		$253K Buy
+3,000
New +$249K ﹤0.01% 2342

Other funds holding LLY

Lilly Endowment
Lilly Endowment Indiananapolis, Indiana $108B AUM 53.87% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
PNC Financial Services Group
PNC Financial Services Group Pittsburgh, Pennsylvania $173B AUM 20.72% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
Capital Research Global Investors
Capital Research Global Investors Los Angeles, California $645B AUM 30.41% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Capital World Investors
Capital World Investors Los Angeles, California $733B AUM 35.63% 1-Year Est. Return

Two Sigma Investments's LLY Position: Q1 2026 in Review

Two Sigma Investments increased its Eli Lilly (LLY) stake by 394% in Q1 2026, buying an estimated $52.2M and bringing the position to 64,550 shares worth $59.4M. The position accounts for 0.05% of the portfolio, ranked #430.

Two Sigma Investments first reported a position in LLY in Q2 2013 and has held it in 35 quarters since. The position peaked at $249M in Q4 2024. 4,353 funds tracked by Wall St. Rank hold LLY as of Q1 2026.

  • Two Sigma Investments held 64,550 shares of Eli Lilly worth $59.4M as of Q1 2026.
  • Two Sigma Investments bought 51,482 Eli Lilly shares in Q1 2026, an estimated $52.2M.
  • Eli Lilly made up 0.05% of Two Sigma Investments's portfolio in Q1 2026, its #430 holding.
  • Two Sigma Investments first reported a position in Eli Lilly in Q2 2013 and has held it in 35 quarters since.
  • Two Sigma Investments's Eli Lilly position peaked at $249M in Q4 2024.
  • 4,353 funds tracked by Wall St. Rank held Eli Lilly as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.