Eli Lilly
4,449 hedge funds and large institutions have $843B invested in Eli Lilly in 2025 Q4 according to their latest regulatory filings, with 734 funds opening new positions, 1,698 increasing their positions, 1,614 reducing their positions, and 110 closing their positions.
567% more first-time investments, than exits
New positions opened: 734 | Existing positions closed: 110
93% more funds holding in top 10
Funds holding in top 10: 254 → 489 (+235)
44% more capital invested
Capital invested by funds: $584B → $843B (+$259B)
14% more funds holding
Funds holding: 3,904 → 4,449 (+545)
2.14% more ownership
Funds ownership: 80.85% → 82.99% (+2.1%)
5% more repeat investments, than reductions
Existing positions increased: 1,698 | Existing positions reduced: 1,614
3% more call options, than puts
Call options by funds: $17.2B | Put options by funds: $16.7B
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
JP Morgan Chase
New York
|
+$2.61B |
| 2 |
Fidelity Investments
Boston,
Massachusetts
|
+$1.48B |
| 3 |
T. Rowe Price Associates
Baltimore,
Maryland
|
+$1.37B |
| 4 |
Wells Fargo
San Francisco,
California
|
+$1.06B |
| 5 |
Marshall Wace
London,
United Kingdom
|
+$999M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Lilly Endowment
Indiananapolis,
Indiana
|
-$3.16B |
| 2 |
Primecap Management
Pasadena,
California
|
-$1.46B |
| 3 |
Wellington Management Group
Boston,
Massachusetts
|
-$1.15B |
| 4 |
Edgewood Management
Greenwich,
Connecticut
|
-$883M |
| 5 |
Goldman Sachs
New York
|
-$674M |
LLY Hedge Fund Activity: Q4 2025 in Review
4,449 of the 8,284 institutional investors tracked by Wall St. Rank reported a position in Eli Lilly (LLY) for Q4 2025, worth a combined $843B — up 44% from $584B a quarter earlier.
Buyers outnumbered sellers: 734 funds opened new LLY positions and 110 closed out — a net gain of 624 holders — while 1,698 added to existing stakes and 1,614 trimmed.
The largest buyer was JP Morgan Chase, adding an estimated $2.61B. The largest seller was Lilly Endowment, cutting an estimated $3.16B.
- 4,449 institutional investors held Eli Lilly (LLY) as of Q4 2025, up from 3,904 in Q3 2025.
- Funds reported $843B of Eli Lilly stock for Q4 2025, up 44% quarter-over-quarter.
- 734 funds opened new Eli Lilly positions in Q4 2025 and 110 closed out, a net change of +624 holders.
- The largest Eli Lilly buyer in Q4 2025 was JP Morgan Chase, an estimated $2.61B added.
- The largest Eli Lilly seller in Q4 2025 was Lilly Endowment, an estimated $3.16B sold.
Based on aggregated 13F filings for Q4 2025.