Two Sigma Investments
FOLD

Two Sigma Investments’s Amicus Therapeutics FOLD Stock Holding History

Two Sigma Investments’s Portfolio FOLD Stock Details FOLD Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$11.3M Sell
781,741
-691,600
-47% -$9.91M 0.01% 1328
2025
Q4 		$21M Buy
1,473,341
+498,466
+51% +$4.9M 0.03% 706
2025
Q3 		$7.68M Buy
974,875
+242,140
+33% +$1.72M 0.01% 1119
2025
Q2 		$4.2M Sell
732,735
-660,034
-47% -$4.26M 0.01% 1340
2025
Q1 		$11.4M Buy
1,392,769
+1,095,326
+368% +$10.1M 0.02% 716
2024
Q4 		$2.8M Buy
297,443
+171,480
+136% +$1.78M 0.01% 1482
2024
Q3 		$1.35M Sell
125,963
-9,534
-7% -$104K ﹤0.01% 1938
2024
Q2 		$1.34M Buy
135,497
+14,961
+12% +$154K ﹤0.01% 1808
2024
Q1 		$1.42M Buy
120,536
+75,183
+166% +$961K ﹤0.01% 1736
2023
Q4 		$644K Buy
45,353
+2,795
+7% +$31.7K ﹤0.01% 2328
2023
Q3 		$518K Sell
42,558
-5,778
-12% -$74.5K ﹤0.01% 2262
2023
Q2 		$607K Sell
48,336
-5,997
-11% -$71.2K ﹤0.01% 2237
2023
Q1 		$603K Buy
54,333
+21,950
+68% +$271K ﹤0.01% 2125
2022
Q4 		$395K Sell
32,383
-442,521
-93% -$4.98M ﹤0.01% 2122
2022
Q3 		$4.96M Buy
474,904
+112,621
+31% +$1.25M 0.02% 763
2022
Q2 		$3.89M Sell
362,283
-80,800
-18% -$665K 0.01% 878
2022
Q1 		$4.2M Sell
443,083
-1,186,107
-73% -$11.1M 0.01% 997
2021
Q4 		$18.8M Buy
1,629,190
+519,221
+47% +$5.79M 0.04% 500
2021
Q3 		$10.6M Buy
1,109,969
+480,388
+76% +$4.91M 0.02% 752
2021
Q2 		$6.07M Sell
629,581
-1,724,507
-73% -$16.8M 0.01% 1086
2021
Q1 		$23.3M Buy
2,354,088
+953,295
+68% +$14.8M 0.06% 376
2020
Q4 		$32.3M Buy
1,400,793
+668,280
+91% +$13.7M 0.09% 249
2020
Q3 		$10.3M Buy
732,513
+207,195
+39% +$3.02M 0.04% 496
2020
Q2 		$7.92M Buy
525,318
+438,711
+507% +$5.35M 0.04% 467
2020
Q1 		$800K Sell
86,607
-551,825
-86% -$5.25M 0.01% 1589
2019
Q4 		$6.22M Buy
638,432
+139,685
+28% +$1.28M 0.02% 834
2019
Q3 		$4M Buy
498,747
+365,331
+274% +$3.97M 0.01% 980
2019
Q2 		$1.67M Buy
133,416
+62,086
+87% +$788K 0.01% 1574
2019
Q1 		$970K Buy
+71,330
New +$871K ﹤0.01% 1851
2018
Q4 		– Sell
-26,845
Closed -$325K – 3160
2018
Q3 		$325K Buy
+26,845
New +$375K ﹤0.01% 2720
2018
Q2 		– Sell
-11,508
Closed -$173K – 3412
2018
Q1 		$173K Sell
11,508
-325,432
-97% -$4.95M ﹤0.01% 3000
2017
Q4 		$4.85M Buy
336,940
+77,049
+30% +$1.06M 0.02% 915
2017
Q3 		$3.92M Buy
+259,891
New +$3.44M 0.01% 915
2015
Q1 		– Sell
-427,502
Closed -$3.56M – 2696
2014
Q4 		$3.56M Sell
427,502
-56,563
-12% -$388K 0.02% 769
2014
Q3 		$2.88M Buy
484,065
+409,683
+551% +$2.15M 0.01% 767
2014
Q2 		$248K Buy
74,382
+23,037
+45% +$54.1K ﹤0.01% 1907
2014
Q1 		$106K Buy
51,345
+32,587
+174% +$81.5K ﹤0.01% 1881
2013
Q4 		$44K Buy
+18,758
New +$41.2K ﹤0.01% 2125

Other funds holding FOLD

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
PCM
Pentwater Capital Management Naples, Florida $19.3B AUM 58.13% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
GCL
Glazer Capital LLC New York $4.71B AUM 81.93% 1-Year Est. Return
Fidelity International
Fidelity International Hamilton, Bermuda $129B AUM 30.83% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT) London, United Kingdom $89.9B AUM 20.22% 1-Year Est. Return

Two Sigma Investments's FOLD Position: Q1 2026 in Review

Two Sigma Investments reduced its Amicus Therapeutics (FOLD) stake by 47% in Q1 2026, selling an estimated $9.91M and leaving 781,741 shares worth $11.3M. The position accounts for 0.01% of the portfolio, ranked #1328.

Two Sigma Investments first reported a position in FOLD in Q4 2013 and has held it in 38 quarters since. The position peaked at $32.3M in Q4 2020. 298 funds tracked by Wall St. Rank hold FOLD as of Q1 2026.

  • Two Sigma Investments held 781,741 shares of Amicus Therapeutics worth $11.3M as of Q1 2026.
  • Two Sigma Investments sold 691,600 Amicus Therapeutics shares in Q1 2026, an estimated $9.91M.
  • Amicus Therapeutics made up 0.01% of Two Sigma Investments's portfolio in Q1 2026, its #1328 holding.
  • Two Sigma Investments first reported a position in Amicus Therapeutics in Q4 2013 and has held it in 38 quarters since.
  • Two Sigma Investments's Amicus Therapeutics position peaked at $32.3M in Q4 2020.
  • 298 funds tracked by Wall St. Rank held Amicus Therapeutics as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.