Amicus Therapeutics
FOLD
FOLD was delisted on the 24th of April, 2026.
332 hedge funds and large institutions have $4.57B invested in Amicus Therapeutics in 2025 Q4 according to their latest regulatory filings, with 97 funds opening new positions, 112 increasing their positions, 85 reducing their positions, and 44 closing their positions.
225% more funds holding in top 10
Funds holding in top 10: 4 → 13 (+9)
120% more first-time investments, than exits
New positions opened: 97 | Existing positions closed: 44
86% more capital invested
Capital invested by funds: $2.46B → $4.57B (+$2.11B)
32% more repeat investments, than reductions
Existing positions increased: 112 | Existing positions reduced: 85
16% more funds holding
Funds holding: 287 → 332 (+45)
2.77% more ownership
Funds ownership: 101.3% → 104.07% (+2.8%)
19% less call options, than puts
Call options by funds: $18.8M | Put options by funds: $23.1M
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
HI
HBK Investments
Dallas,
Texas
|
+$150M |
| 2 |
PCM
Pentwater Capital Management
Naples,
Florida
|
+$113M |
| 3 |
BG
Bellevue Group
Kuesnacht,
Switzerland
|
+$105M |
| 4 |
BlackRock
New York
|
+$65.6M |
| 5 |
SFM
Soros Fund Management
New York
|
+$49.1M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Wellington Management Group
Boston,
Massachusetts
|
-$268M |
| 2 |
ACA
Avoro Capital Advisors
New York
|
-$118M |
| 3 |
Millennium Management
New York
|
-$86.6M |
| 4 |
VPC
Vestal Point Capital
New York
|
-$76.8M |
| 5 |
William Blair Investment Management
Chicago,
Illinois
|
-$50.3M |
FOLD Hedge Fund Activity: Q4 2025 in Review
332 of the 8,227 institutional investors tracked by Wall St. Rank reported a position in Amicus Therapeutics (FOLD) for Q4 2025, worth a combined $4.57B — up 86% from $2.46B a quarter earlier.
Buyers outnumbered sellers: 97 funds opened new FOLD positions and 44 closed out — a net gain of 53 holders — while 112 added to existing stakes and 85 trimmed.
The largest buyer was HBK Investments, opening a new position worth an estimated $150M. The largest seller was Wellington Management Group, cutting an estimated $268M.
- 332 institutional investors held Amicus Therapeutics (FOLD) as of Q4 2025, up from 287 in Q3 2025.
- Funds reported $4.57B of Amicus Therapeutics stock for Q4 2025, up 86% quarter-over-quarter.
- 97 funds opened new Amicus Therapeutics positions in Q4 2025 and 44 closed out, a net change of +53 holders.
- The largest Amicus Therapeutics buyer in Q4 2025 was HBK Investments, an estimated $150M added.
- The largest Amicus Therapeutics seller in Q4 2025 was Wellington Management Group, an estimated $268M sold.
Based on aggregated 13F filings for Q4 2025.