Two Sigma Investments
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Two Sigma Investments’s Caribou Biosciences CRBU Stock Holding History

Two Sigma Investments’s Portfolio CRBU Stock Details CRBU Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$3.34M Buy
1,759,934
+739,855
+73% +$1.27M ﹤0.01% 2349
2025
Q4 		$1.62M Buy
1,020,079
+236,489
+30% +$496K ﹤0.01% 2592
2025
Q3 		$1.83M Sell
783,590
-144,935
-16% -$274K ﹤0.01% 2192
2025
Q2 		$1.17M Sell
928,525
-52,773
-5% -$51.9K ﹤0.01% 2154
2025
Q1 		$896K Sell
981,298
-137,398
-12% -$179K ﹤0.01% 2238
2024
Q4 		$1.78M Buy
1,118,696
+214,239
+24% +$431K ﹤0.01% 1799
2024
Q3 		$1.77M Sell
904,457
-214,728
-19% -$440K ﹤0.01% 1753
2024
Q2 		$1.84M Buy
1,119,185
+889,438
+387% +$2.84M ﹤0.01% 1612
2024
Q1 		$1.18M Sell
229,747
-274,852
-54% -$1.69M ﹤0.01% 1848
2023
Q4 		$2.89M Buy
504,599
+307,984
+157% +$1.52M 0.01% 1280
2023
Q3 		$940K Buy
196,615
+146,989
+296% +$912K ﹤0.01% 1974
2023
Q2 		$211K Buy
+49,626
New +$223K ﹤0.01% 2631
2023
Q1 		– Sell
-121,924
Closed -$766K – 2998
2022
Q4 		$766K Buy
+121,924
New +$1.08M ﹤0.01% 1839
2022
Q2 		– Sell
-24,456
Closed -$225K – 2578
2022
Q1 		$225K Buy
+24,456
New +$258K ﹤0.01% 2307

Other funds holding CRBU

P
Pfizer New York $239M AUM 232.47% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Renaissance Technologies
Renaissance Technologies New York $63.9B AUM 45.56% 1-Year Est. Return
KCM
Kynam Capital Management Princeton, New Jersey $1.62B AUM 138.67% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Bank of America
Bank of America Charlotte, North Carolina $1.37T AUM 24.88% 1-Year Est. Return
Aberdeen Group
Aberdeen Group Edinburgh, United Kingdom $61.9B AUM 29.81% 1-Year Est. Return
Marshall Wace
Marshall Wace London, United Kingdom $100B AUM 35.1% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

Two Sigma Investments's CRBU Position: Q1 2026 in Review

Two Sigma Investments increased its Caribou Biosciences (CRBU) stake by 73% in Q1 2026, buying an estimated $1.27M and bringing the position to 1,759,934 shares worth $3.34M. The position accounts for ﹤0.01% of the portfolio, ranked #2349.

Two Sigma Investments first reported a position in CRBU in Q1 2022 and has held it in 14 quarters since. 137 funds tracked by Wall St. Rank hold CRBU as of Q1 2026.

  • Two Sigma Investments held 1,759,934 shares of Caribou Biosciences worth $3.34M as of Q1 2026.
  • Two Sigma Investments bought 739,855 Caribou Biosciences shares in Q1 2026, an estimated $1.27M.
  • Caribou Biosciences made up ﹤0.01% of Two Sigma Investments's portfolio in Q1 2026, its #2349 holding.
  • Two Sigma Investments first reported a position in Caribou Biosciences in Q1 2022 and has held it in 14 quarters since.
  • 137 funds tracked by Wall St. Rank held Caribou Biosciences as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.