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Caribou Biosciences

117 hedge funds and large institutions have $87M invested in Caribou Biosciences in 2025 Q3 according to their latest regulatory filings, with 16 funds opening new positions, 21 increasing their positions, 47 reducing their positions, and 28 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

68% more capital invested

Capital invested by funds: $51.9M → $87M (+$35.1M)

3.93% less ownership

Funds ownership: 43.83%39.9% (-3.9%)

9% less funds holding

Funds holding: 129117 (-12)

38% less call options, than puts

Call options by funds: $191K | Put options by funds: $307K

43% less first-time investments, than exits

New positions opened: 16 | Existing positions closed: 28

55% less repeat investments, than reductions

Existing positions increased: 21 | Existing positions reduced: 47

Holders
117
Holders Change
-12
Holders Change %
-9.3%
% of All Funds
1.54%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
16
Increased
21
Reduced
47
Closed
28
Calls
$191K
Puts
$307K
Net Calls
-$116K
Net Calls Change
-$172K
Name Holding Trade Value Shares
Change
Change in
Stake
P
1
Pfizer
New York
$10.9M
Vanguard Group
2
Vanguard Group
Pennsylvania
$9.85M +$259K +137,060 +3%
Millennium Management
3
Millennium Management
New York
$7.49M +$3.14M +1,665,946 +107%
KCM
4
Kynam Capital Management
New Jersey
$7.15M
BlackRock
5
BlackRock
New York
$3.4M -$801K -424,156 -23%
Aberdeen Group
6
Aberdeen Group
United Kingdom
$3.24M +$928K +491,326 +55%
PHS
7
PFM Health Sciences
California
$3.17M
Two Sigma Advisers
8
Two Sigma Advisers
New York
$2.86M -$416K -220,400 -15%
Dimensional Fund Advisors
9
Dimensional Fund Advisors
Texas
$2.82M -$183K -97,045 -7%
Bank of America
10
Bank of America
North Carolina
$2.5M +$501K +265,542 +33%
Geode Capital Management
11
Geode Capital Management
Massachusetts
$2.3M +$7.92K +4,197 +0.4%
Two Sigma Investments
12
Two Sigma Investments
New York
$1.83M -$274K -144,935 -16%
Renaissance Technologies
13
Renaissance Technologies
New York
$1.82M +$469K +248,300 +47%
PFCS
14
Pale Fire Capital SE
Czech Republic
$1.81M
Fidelity Investments
15
Fidelity Investments
Massachusetts
$1.7M -$829 -439 -0.1%
MC
16
Maverick Capital
Texas
$1.52M
Cambridge Investment Research Advisors
17
Cambridge Investment Research Advisors
Iowa
$1.36M -$3.89K -2,059 -0.4%
Royal Bank of Canada
18
Royal Bank of Canada
Ontario, Canada
$1.34M -$47.1K -24,964 -4%
SSA
19
Schonfeld Strategic Advisors
New York
$1.3M -$3.24M -1,714,290 -75%
Charles Schwab
20
Charles Schwab
California
$1.3M +$54.8K +29,025 +5%
Jane Street
21
Jane Street
New York
$1.12M -$7.88K -4,172 -0.9%
7IH
22
72 Investment Holdings
Connecticut
$1.1M
Susquehanna International Group
23
Susquehanna International Group
Pennsylvania
$1.04M +$342K +180,972 +68%
XT
24
XTX Topco
Cayman Islands
$1.03M +$635K +336,308 +320%
State Street
25
State Street
Massachusetts
$900K +$53K +28,100 +8%

CRBU Hedge Fund Activity: Q3 2025 in Review

117 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Caribou Biosciences (CRBU) for Q3 2025, worth a combined $87M — up 68% from $51.9M a quarter earlier.

Sellers outnumbered buyers: 28 funds closed out of CRBU and 16 opened new positions — a net loss of 12 holders — while 47 trimmed existing stakes and 21 added.

The largest buyer was Millennium Management, adding an estimated $3.14M. The largest seller was Schonfeld Strategic Advisors, cutting an estimated $3.24M.

  • 117 institutional investors held Caribou Biosciences (CRBU) as of Q3 2025, down from 129 in Q2 2025.
  • Funds reported $87M of Caribou Biosciences stock for Q3 2025, up 68% quarter-over-quarter.
  • 16 funds opened new Caribou Biosciences positions in Q3 2025 and 28 closed out, a net change of -12 holders.
  • The largest Caribou Biosciences buyer in Q3 2025 was Millennium Management, an estimated $3.14M added.
  • The largest Caribou Biosciences seller in Q3 2025 was Schonfeld Strategic Advisors, an estimated $3.24M sold.

Based on aggregated 13F filings for Q3 2025.