Two Sigma Advisers
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Two Sigma Advisers’s Tango Therapeutics TNGX Stock Holding History

Two Sigma Advisers’s Portfolio TNGX Stock Details TNGX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-94,100
Closed -$790K – 2625
2025
Q3 		$790K Buy
+94,100
New +$637K ﹤0.01% 1573
2025
Q2 		– Sell
-97,000
Closed -$133K – 2545
2025
Q1 		$133K Buy
97,000
+70,800
+270% +$174K ﹤0.01% 2205
2024
Q4 		$81K Buy
+26,200
New +$122K ﹤0.01% 2244
2024
Q2 		– Sell
-10,500
Closed -$83.4K – 2672
2024
Q1 		$83.4K Buy
+10,500
New +$113K ﹤0.01% 2316
2023
Q3 		– Sell
-10,100
Closed -$33.5K – 2575
2023
Q2 		$33.5K Buy
+10,100
New +$36.3K ﹤0.01% 2298

Other funds holding TNGX

FCM
Farallon Capital Management San Francisco, California $17.5B AUM 50.95% 1-Year Est. Return
TCM
TCG Crossover Management Palo Alto, California $3.5B AUM 1,165.83% 1-Year Est. Return
BCM
Boxer Capital Management San Diego, California $762M AUM 1,125.36% 1-Year Est. Return
Adage Capital Partners
Adage Capital Partners Boston, Massachusetts $64.8B AUM 42.7% 1-Year Est. Return
WP
Woodline Partners San Francisco, California $26.4B AUM 44.85% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $3.61B AUM 203.3% 1-Year Est. Return
TGI
TRV GP IV Boston, Massachusetts $267M AUM 965.83% 1-Year Est. Return
NI
Nextech Invest Zurich, Switzerland $1.42B AUM 304.47% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return

Two Sigma Advisers's TNGX Position: Q4 2025 in Review

Two Sigma Advisers sold out of Tango Therapeutics (TNGX) in Q4 2025, closing a stake of 94,100 shares — an estimated $790K sold.

Two Sigma Advisers first reported a position in TNGX in Q2 2023 and held it in 5 quarters. The position peaked at $790K in Q3 2025. 170 funds tracked by Wall St. Rank hold TNGX as of Q4 2025.

  • Two Sigma Advisers reported no remaining Tango Therapeutics position as of Q4 2025 after selling out during the quarter.
  • Two Sigma Advisers sold 94,100 Tango Therapeutics shares in Q4 2025, an estimated $790K.
  • Two Sigma Advisers first reported a position in Tango Therapeutics in Q2 2023 and held it in 5 quarters.
  • Two Sigma Advisers's Tango Therapeutics position peaked at $790K in Q3 2025.
  • 170 funds tracked by Wall St. Rank held Tango Therapeutics as of Q4 2025.

Based on Two Sigma Advisers's 13F filing for Q4 2025, filed 17 Feb 2026.