Two Sigma Advisers
ANVS icon

Two Sigma Advisers’s Annovis Bio ANVS Stock Holding History

Two Sigma Advisers’s Portfolio ANVS Stock Details ANVS Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		– Sell
-45,221
Closed -$156K – 132
2025
Q4 		$156K Buy
+45,221
New +$136K ﹤0.01% 2160
2025
Q2 		– Sell
-92,921
Closed -$139K – 2312
2025
Q1 		$139K Buy
+92,921
New +$284K ﹤0.01% 2199
2022
Q4 		– Sell
-11,800
Closed -$162K – 2510
2022
Q3 		$162K Sell
11,800
-6,200
-34% -$81.5K ﹤0.01% 2242
2022
Q2 		$204K Sell
18,000
-28,400
-61% -$310K ﹤0.01% 2271
2022
Q1 		$619K Sell
46,400
-17,400
-27% -$251K ﹤0.01% 1878
2021
Q4 		$1.12M Buy
63,800
+33,600
+111% +$866K ﹤0.01% 1508
2021
Q3 		$959K Buy
30,200
+27,200
+907% +$1.56M ﹤0.01% 1639
2021
Q2 		$257K Buy
+3,000
New +$139K ﹤0.01% 2188
2020
Q4 		– Sell
-13,300
Closed -$64K – 2375
2020
Q3 		$64K Buy
+13,300
New +$71.2K ﹤0.01% 2305

Other funds holding ANVS

Marshall Wace
Marshall Wace London, United Kingdom $100B AUM 35.1% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Two Sigma Investments
Two Sigma Investments New York $124B AUM 33.93% 1-Year Est. Return
Renaissance Technologies
Renaissance Technologies New York $63.9B AUM 45.56% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Susquehanna International Group
Susquehanna International Group Bala Cynwyd, Pennsylvania $893B AUM 36.07% 1-Year Est. Return
Northern Trust
Northern Trust Chicago, Illinois $757B AUM 28.64% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
VFT
Vanguard Fiduciary Trust Malvern, Pennsylvania $396B AUM
MFG
Merit Financial Group Alpharetta, Georgia $16.4B AUM 25.17% 1-Year Est. Return

Two Sigma Advisers's ANVS Position: Q1 2026 in Review

Two Sigma Advisers sold out of Annovis Bio (ANVS) in Q1 2026, closing a stake of 45,221 shares — an estimated $156K sold.

Two Sigma Advisers first reported a position in ANVS in Q3 2020 and held it in 9 quarters. The position peaked at $1.12M in Q4 2021. 56 funds tracked by Wall St. Rank hold ANVS as of Q1 2026.

  • Two Sigma Advisers reported no remaining Annovis Bio position as of Q1 2026 after selling out during the quarter.
  • Two Sigma Advisers sold 45,221 Annovis Bio shares in Q1 2026, an estimated $156K.
  • Two Sigma Advisers first reported a position in Annovis Bio in Q3 2020 and held it in 9 quarters.
  • Two Sigma Advisers's Annovis Bio position peaked at $1.12M in Q4 2021.
  • 56 funds tracked by Wall St. Rank held Annovis Bio as of Q1 2026.

Based on Two Sigma Advisers's 13F filing for Q1 2026.