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TGI

TRV GP IV Portfolio holdings

AUM $267M
1-Year Est. Return 965.83%
This Fund
S&P 500
This Quarter Est. Return
+44.93%
1 Year Est. Return
+965.83%
3 Year Est. Return
+686.22%
5 Year Est. Return
+581.56%
10 Year Est. Return
–
AUM
$255M
AUM Growth
-$18.8M
Cap. Flow
-$107M
Cap. Flow %
-41.78%
Top 10 Hldgs %
100%
Holding
2
New
–
Increased
–
Reduced
2
Closed
–

Top Buys

No buys this quarter

Top Sells

Rank Stock Value
1
MAZE
Maze Therapeutics
MAZE
+$55M
2
TNGX icon
Tango Therapeutics
TNGX
+$51.6M

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
MAZE
1
Maze Therapeutics
MAZE
$1.49B
$185M 72.65%
4,473,958
-1,600,000
-26% -$55M
TNGX icon
2
Tango Therapeutics
TNGX
$4.43B
$69.8M 27.35%
7,874,574
-5,989,401
-43% -$51.6M

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TRV GP IV's Q4 2025 Portfolio in Review

As of Q4 2025, TRV GP IV held 2 positions worth $255M, down 6.9% from $274M the previous quarter. Its ten largest holdings account for 100% of the portfolio.

TRV GP IV withdrew a net $107M in Q4 2025, reducing 2 holdings. Its largest reduction was Maze Therapeutics, cutting an estimated $55M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, unchanged from a quarter earlier.

  • TRV GP IV's biggest Q4 2025 reduction was Maze Therapeutics, cutting an estimated $55M.
  • TRV GP IV's ten largest holdings make up 100% of its $255M portfolio in Q4 2025.
  • TRV GP IV opened 0 new positions and closed 0 in Q4 2025.
  • TRV GP IV's portfolio value fell 6.9% quarter-over-quarter to $255M.

Based on TRV GP IV's 13F filing for Q4 2025, filed 13 Feb 2026.