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TGI

TRV GP IV Portfolio holdings

AUM $267M
1-Year Est. Return 965.83%
This Fund
S&P 500
This Quarter Est. Return
+91.24%
1 Year Est. Return
+965.83%
3 Year Est. Return
+686.22%
5 Year Est. Return
+581.56%
10 Year Est. Return
–
AUM
$274M
AUM Growth
+$111M
Cap. Flow
-$22.7M
Cap. Flow %
-8.3%
Top 10 Hldgs %
100%
Holding
3
New
–
Increased
–
Reduced
1
Closed
1

Top Buys

No buys this quarter

Top Sells

Rank Stock Value
1
TNGX icon
Tango Therapeutics
TNGX
+$20.3M
2
PLRX icon
Pliant Therapeutics
PLRX
+$2.47M

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
MAZE
1
Maze Therapeutics
MAZE
$1.49B
$157M 57.49%
6,073,958
– –
TNGX icon
2
Tango Therapeutics
TNGX
$4.43B
$116M 42.51%
13,863,975
-2,995,100
-18% -$20.3M
PLRX icon
3
Pliant Therapeutics
PLRX
$64.4M
– –
-2,132,867
Closed -$2.47M

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TRV GP IV's Q3 2025 Portfolio in Review

As of Q3 2025, TRV GP IV held 3 positions worth $274M, up 68% from $163M the previous quarter. Its ten largest holdings account for 100% of the portfolio.

TRV GP IV withdrew a net $22.7M in Q3 2025, closing 1 position and reducing 1 holding. Its most notable exit was Pliant Therapeutics, an estimated $2.47M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, unchanged from a quarter earlier.

  • TRV GP IV's biggest Q3 2025 reduction was Tango Therapeutics, cutting an estimated $20.3M.
  • TRV GP IV fully exited Pliant Therapeutics in Q3 2025, selling an estimated $2.47M.
  • TRV GP IV's ten largest holdings make up 100% of its $274M portfolio in Q3 2025.
  • TRV GP IV opened 0 new positions and closed 1 in Q3 2025.
  • TRV GP IV's portfolio value rose 68% quarter-over-quarter to $274M.

Based on TRV GP IV's 13F filing for Q3 2025, filed 13 Nov 2025.