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Suvretta Capital Management Portfolio holdings

AUM $3.92B
1-Year Est. Return 86.67%
This Fund
S&P 500
This Quarter Est. Return
+18.5%
1 Year Est. Return
+86.67%
3 Year Est. Return
+295.96%
5 Year Est. Return
+364.48%
10 Year Est. Return
+2,073.65%
AUM
$4.88B
AUM Growth
+$975M
Cap. Flow
+$671M
Cap. Flow %
13.75%
Top 10 Hldgs %
41.91%
Holding
108
New
15
Increased
25
Reduced
14
Closed
15

Top Buys

Rank Stock Value
1
SYY icon
Sysco
SYY
+$82.5M
2
LEGN icon
Legend Biotech
LEGN
+$79.9M
3
BHVN icon
Biohaven
BHVN
+$57.8M
4
NOW icon
ServiceNow
NOW
+$47.9M
5
QURE icon
uniQure
QURE
+$47M

Top Sells

Rank Stock Value
1
ETNB
89bio
ETNB
+$122M
2
KDP icon
Keurig Dr Pepper
KDP
+$40.1M
3
FERG icon
Ferguson
FERG
+$35.1M
4
RNAM
Avidity Biosciences
RNAM
+$32.7M
5
MLYS icon
Mineralys Therapeutics
MLYS
+$23.8M

Sector Composition

Rank Sector Weight
1 Healthcare 51.05%
2 Technology 10.74%
3 Consumer Discretionary 6.34%
4 Financials 4.61%
5 Consumer Staples 3.62%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
MRVL icon
101
Marvell Technology
MRVL
$196B
– –
-272,300
Closed -$22.9M
PINS icon
102
Pinterest
PINS
$13.4B
– –
-497,185
Closed -$16M
REGN icon
103
Regeneron Pharmaceuticals
REGN
$80.8B
– –
-17,730
Closed -$9.97M
RNAM
104
DELISTED
Avidity Biosciences
RNAM
– –
-750,000
Closed -$32.7M
SNOW icon
105
Snowflake
SNOW
$115B
– –
-89,200
Closed -$20.1M
STRO icon
106
Sutro Biopharma
STRO
$421M
– –
-648,832
Closed -$5.63M
XBI icon
107
PUT
State Street SPDR S&P Biotech ETF
XBI
$10.3B
– –
-500,000
Closed -$50.1M
PACS icon
108
PACS Group
PACS
$7.67B
– –
-20,000
Closed -$275K
1 2 3 4
5

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AS
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MSI
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FLSM
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LWCA
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TFM
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USCWA
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Suvretta Capital Management's Q4 2025 Portfolio in Review

As of Q4 2025, Suvretta Capital Management held 108 positions worth $4.88B, up 25% from $3.91B the previous quarter. Its ten largest holdings account for 42% of the portfolio.

Suvretta Capital Management deployed $671M of net new capital in Q4 2025, opening 15 new positions and adding to 25 existing holdings. Its largest new stake was Sysco: 1,083,790 shares worth $79.9M.

By sector, the portfolio is most concentrated in Healthcare at 51% of assets, up from 51% a quarter earlier, followed by Technology and Consumer Discretionary.

On the sell side, the largest reduction was Ferguson, an estimated $35.1M trimmed.

  • Suvretta Capital Management's largest Q4 2025 buy was Sysco: 1,083,790 shares worth $79.9M.
  • Suvretta Capital Management added most to Legend Biotech in Q4 2025, an estimated $79.9M increase.
  • Suvretta Capital Management's biggest Q4 2025 reduction was Ferguson, cutting an estimated $35.1M.
  • Suvretta Capital Management fully exited 89bio in Q4 2025, selling an estimated $122M.
  • Suvretta Capital Management's ten largest holdings make up 42% of its $4.88B portfolio in Q4 2025.
  • Suvretta Capital Management opened 15 new positions and closed 15 in Q4 2025.
  • Suvretta Capital Management's portfolio value rose 25% quarter-over-quarter to $4.88B.

Based on Suvretta Capital Management's 13F filing for Q4 2025, filed 17 Feb 2026.