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Suvretta Capital Management Portfolio holdings

AUM $3.92B
1-Year Est. Return 86.67%
This Fund
S&P 500
This Quarter Est. Return
+18.5%
1 Year Est. Return
+86.67%
3 Year Est. Return
+295.96%
5 Year Est. Return
+364.48%
10 Year Est. Return
+2,073.65%
AUM
$4.88B
AUM Growth
+$975M
Cap. Flow
+$671M
Cap. Flow %
13.75%
Top 10 Hldgs %
41.91%
Holding
108
New
15
Increased
25
Reduced
14
Closed
15

Top Buys

Rank Stock Value
1
SYY icon
Sysco
SYY
+$82.5M
2
LEGN icon
Legend Biotech
LEGN
+$79.9M
3
BHVN icon
Biohaven
BHVN
+$57.8M
4
NOW icon
ServiceNow
NOW
+$47.9M
5
QURE icon
uniQure
QURE
+$47M

Top Sells

Rank Stock Value
1
ETNB
89bio
ETNB
+$122M
2
KDP icon
Keurig Dr Pepper
KDP
+$40.1M
3
FERG icon
Ferguson
FERG
+$35.1M
4
RNAM
Avidity Biosciences
RNAM
+$32.7M
5
MLYS icon
Mineralys Therapeutics
MLYS
+$23.8M

Sector Composition

Rank Sector Weight
1 Healthcare 51.05%
2 Technology 10.74%
3 Consumer Discretionary 6.34%
4 Financials 4.61%
5 Consumer Staples 3.62%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
SPY icon
1
PUT
State Street SPDR S&P 500 ETF Trust
SPY
$774B
$546M 11.18%
800,000
– –
ARQT icon
2
Arcutis Biotherapeutics
ARQT
$3.56B
$347M 7.12%
11,964,000
+1,486,000
+14% +$38M
ARKG icon
3
PUT
ARK Genomic Revolution ETF
ARKG
$1.61B
$242M 4.95%
+8,342,300
New +$250M
BNTC icon
4
Benitec Biopharma
BNTC
$439M
$156M 3.19%
11,548,351
+1,671,845
+17% +$23.1M
LEGN icon
5
Legend Biotech
LEGN
$4.31B
$144M 2.94%
6,608,629
+2,790,620
+73% +$79.9M
EYPT icon
6
EyePoint Inc
EYPT
$1.12B
$143M 2.93%
7,827,685
+1,634,970
+26% +$23.2M
RCUS icon
7
Arcus Biosciences
RCUS
$3.44B
$124M 2.53%
5,188,858
+1,500,000
+41% +$30.6M
IMTX icon
8
Immatics
IMTX
$1.31B
$117M 2.41%
11,190,129
-840,000
-7% -$8.48M
BHVN icon
9
Biohaven
BHVN
$2.32B
$116M 2.38%
10,286,937
+4,666,666
+83% +$57.8M
META icon
10
Meta Platforms (Facebook)
META
$1.64T
$112M 2.29%
169,069
-1,904
-1% -$1.27M
APLS
11
DELISTED
Apellis Pharmaceuticals
APLS
$104M 2.13%
4,139,426
+1,261,426
+44% +$29.6M
NVDA icon
12
NVIDIA
NVDA
$4.91T
$99M 2.03%
530,900
+47,365
+10% +$8.82M
KO icon
13
Coca-Cola
KO
$351B
$96.7M 1.98%
1,382,750
-72,330
-5% -$5.04M
GE icon
14
GE Aerospace
GE
$364B
$95.6M 1.96%
310,262
– –
AMZN icon
15
Amazon
AMZN
$2.66T
$93.7M 1.92%
406,146
+187,599
+86% +$42.9M
PVLA
16
Palvella Therapeutics
PVLA
$2.26B
$93.4M 1.91%
892,400
+70,000
+9% +$5.97M
KURA icon
17
Kura Oncology
KURA
$964M
$89.1M 1.83%
8,575,422
+459,422
+6% +$4.82M
BAC icon
18
Bank of America
BAC
$430B
$83.5M 1.71%
1,517,630
+357,300
+31% +$18.9M
AMD icon
19
Advanced Micro Devices
AMD
$808B
$83.4M 1.71%
389,576
-9,223
-2% -$2.07M
HIMS icon
20
PUT
Hims & Hers Health
HIMS
$7.6B
$83.1M 1.7%
+2,559,400
New +$110M
HD icon
21
Home Depot
HD
$338B
$82.9M 1.7%
240,861
+43,550
+22% +$16M
AVBP icon
22
ArriVent BioPharma
AVBP
$1.55B
$82.6M 1.69%
4,106,035
+402,583
+11% +$8.38M
TSM icon
23
TSMC
TSM
$2.07T
$82.5M 1.69%
271,401
-5,800
-2% -$1.7M
SYY icon
24
Sysco
SYY
$39.1B
$79.9M 1.64%
+1,083,790
New +$82.5M
APO icon
25
Apollo Global Management
APO
$69.5B
$78.6M 1.61%
542,890
+111,630
+26% +$14.8M
1
2 3 4 5

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MIM
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AA
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DACG
Donor Advised Charitable Giving San Francisco, California $3.92B AUM 59.92% 1-Year Est. Return
CCM
Channing Capital Management Chicago, Illinois $3.91B AUM 34.32% 1-Year Est. Return
BCP
BSN Capital Partners London, United Kingdom $3.93B AUM 13.09% 1-Year Est. Return
AS
American Securities New York $3.93B AUM 52.22% 1-Year Est. Return
MSI
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FLSM
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Suvretta Capital Management's Q4 2025 Portfolio in Review

As of Q4 2025, Suvretta Capital Management held 108 positions worth $4.88B, up 25% from $3.91B the previous quarter. Its ten largest holdings account for 42% of the portfolio.

Suvretta Capital Management deployed $671M of net new capital in Q4 2025, opening 15 new positions and adding to 25 existing holdings. Its largest new stake was Sysco: 1,083,790 shares worth $79.9M.

By sector, the portfolio is most concentrated in Healthcare at 51% of assets, up from 51% a quarter earlier, followed by Technology and Consumer Discretionary.

On the sell side, the largest reduction was Ferguson, an estimated $35.1M trimmed.

  • Suvretta Capital Management's largest Q4 2025 buy was Sysco: 1,083,790 shares worth $79.9M.
  • Suvretta Capital Management added most to Legend Biotech in Q4 2025, an estimated $79.9M increase.
  • Suvretta Capital Management's biggest Q4 2025 reduction was Ferguson, cutting an estimated $35.1M.
  • Suvretta Capital Management fully exited 89bio in Q4 2025, selling an estimated $122M.
  • Suvretta Capital Management's ten largest holdings make up 42% of its $4.88B portfolio in Q4 2025.
  • Suvretta Capital Management opened 15 new positions and closed 15 in Q4 2025.
  • Suvretta Capital Management's portfolio value rose 25% quarter-over-quarter to $4.88B.

Based on Suvretta Capital Management's 13F filing for Q4 2025, filed 17 Feb 2026.