We are live on ! Find out more
SCM

Suvretta Capital Management Portfolio holdings

AUM $3.92B
1-Year Est. Return 86.67%
This Fund
S&P 500
This Quarter Est. Return
+18.5%
1 Year Est. Return
+86.67%
3 Year Est. Return
+295.96%
5 Year Est. Return
+364.48%
10 Year Est. Return
+2,073.65%
AUM
$4.88B
AUM Growth
+$975M
Cap. Flow
+$671M
Cap. Flow %
13.75%
Top 10 Hldgs %
41.91%
Holding
108
New
15
Increased
25
Reduced
14
Closed
15

Top Buys

Rank Stock Value
1
SYY icon
Sysco
SYY
+$82.5M
2
LEGN icon
Legend Biotech
LEGN
+$79.9M
3
BHVN icon
Biohaven
BHVN
+$57.8M
4
NOW icon
ServiceNow
NOW
+$47.9M
5
QURE icon
uniQure
QURE
+$47M

Top Sells

Rank Stock Value
1
ETNB
89bio
ETNB
+$122M
2
KDP icon
Keurig Dr Pepper
KDP
+$40.1M
3
FERG icon
Ferguson
FERG
+$35.1M
4
RNAM
Avidity Biosciences
RNAM
+$32.7M
5
MLYS icon
Mineralys Therapeutics
MLYS
+$23.8M

Sector Composition

Rank Sector Weight
1 Healthcare 51.05%
2 Technology 10.74%
3 Consumer Discretionary 6.34%
4 Financials 4.61%
5 Consumer Staples 3.62%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
MSFT icon
26
Microsoft
MSFT
$3.71T
$77.2M 1.58%
159,695
+50,240
+46% +$25.2M
KALV
27
DELISTED
KalVista Pharmaceuticals
KALV
$77M 1.58%
4,768,712
– –
CMPX icon
28
Compass Therapeutics
CMPX
$387M
$76.2M 1.56%
14,182,379
+81,220
+0.6% +$375K
FULC icon
29
Fulcrum Therapeutics
FULC
$297M
$74.2M 1.52%
6,561,111
+1,180,111
+22% +$12M
NOW icon
30
ServiceNow
NOW
$129B
$59.7M 1.22%
389,445
+279,445
+254% +$47.9M
DHR icon
31
Danaher
DHR
$144B
$55.9M 1.15%
244,300
-11,500
-4% -$2.53M
MLYS icon
32
Mineralys Therapeutics
MLYS
$2.41B
$55.8M 1.14%
1,538,662
-593,471
-28% -$23.8M
ERAS icon
33
Erasca
ERAS
$6.39B
$53.9M 1.11%
14,502,004
– –
CRM icon
34
Salesforce
CRM
$158B
$53M 1.08%
199,900
+74,650
+60% +$18.6M
GLUE icon
35
Monte Rosa Therapeutics
GLUE
$1.35B
$52.7M 1.08%
3,360,000
– –
CAPR icon
36
Capricor Therapeutics
CAPR
$237M
$51.5M 1.06%
+1,785,610
New +$23.3M
RARE icon
37
Ultragenyx Pharmaceutical
RARE
$2.55B
$46.4M 0.95%
2,019,000
– –
ORCL icon
38
Oracle
ORCL
$423B
$44.1M 0.9%
226,318
– –
MGM icon
39
MGM Resorts International
MGM
$11.2B
$43.9M 0.9%
+1,202,070
New +$40.8M
COF icon
40
Capital One
COF
$134B
$41.7M 0.85%
171,970
-66,800
-28% -$14.9M
TSLA icon
41
Tesla
TSLA
$1.3T
$41M 0.84%
91,252
– –
MSOS icon
42
AdvisorShares Pure US Cannabis ETF
MSOS
$880M
$40.9M 0.84%
8,669,600
+1,502,600
+21% +$6.69M
UNH icon
43
UnitedHealth
UNH
$370B
$36.7M 0.75%
111,320
+15,100
+16% +$5.12M
FERG icon
44
Ferguson
FERG
$49.8B
$35.4M 0.73%
159,190
-147,070
-48% -$35.1M
BSX icon
45
Boston Scientific
BSX
$71.5B
$33.7M 0.69%
353,561
– –
CTNM
46
Contineum Therapeutics
CTNM
$566M
$32.5M 0.67%
2,841,334
+1,121,334
+65% +$12.8M
ZURA icon
47
Zura Bio
ZURA
$567M
$29.2M 0.6%
5,567,001
+94,110
+2% +$372K
QURE icon
48
uniQure
QURE
$3.22B
$29.1M 0.6%
+1,216,734
New +$47M
PROK icon
49
ProKidney
PROK
$337M
$27.6M 0.57%
12,341,266
– –
COHR icon
50
Coherent
COHR
$74.2B
$25.5M 0.52%
+137,930
New +$20.6M
1
2
3 4 5

Similar funds

MIM
Meridiem Investment Management London, United Kingdom $3.92B AUM 1.64% 1-Year Est. Return
BCP
BSN Capital Partners London, United Kingdom $3.93B AUM 13.09% 1-Year Est. Return
AS
American Securities New York $3.93B AUM 52.22% 1-Year Est. Return
MSI
Mitsui Sumitomo Insurance Tokyo, Japan $3.9B AUM
FLSM
Frazier Life Sciences Management Palo Alto, California $3.89B AUM 201.1% 1-Year Est. Return
LWCA
Locust Wood Capital Advisers New York $3.95B AUM 33.1% 1-Year Est. Return
TFM
Trian Fund Management New York $3.86B AUM 26.59% 1-Year Est. Return
USCWA
U.S. Capital Wealth Advisors Austin, Texas $3.98B AUM 22.36% 1-Year Est. Return

Suvretta Capital Management's Q4 2025 Portfolio in Review

As of Q4 2025, Suvretta Capital Management held 108 positions worth $4.88B, up 25% from $3.91B the previous quarter. Its ten largest holdings account for 42% of the portfolio.

Suvretta Capital Management deployed $671M of net new capital in Q4 2025, opening 15 new positions and adding to 25 existing holdings. Its largest new stake was Sysco: 1,083,790 shares worth $79.9M.

By sector, the portfolio is most concentrated in Healthcare at 51% of assets, up from 51% a quarter earlier, followed by Technology and Consumer Discretionary.

On the sell side, the largest reduction was Ferguson, an estimated $35.1M trimmed.

  • Suvretta Capital Management's largest Q4 2025 buy was Sysco: 1,083,790 shares worth $79.9M.
  • Suvretta Capital Management added most to Legend Biotech in Q4 2025, an estimated $79.9M increase.
  • Suvretta Capital Management's biggest Q4 2025 reduction was Ferguson, cutting an estimated $35.1M.
  • Suvretta Capital Management fully exited 89bio in Q4 2025, selling an estimated $122M.
  • Suvretta Capital Management's ten largest holdings make up 42% of its $4.88B portfolio in Q4 2025.
  • Suvretta Capital Management opened 15 new positions and closed 15 in Q4 2025.
  • Suvretta Capital Management's portfolio value rose 25% quarter-over-quarter to $4.88B.

Based on Suvretta Capital Management's 13F filing for Q4 2025, filed 17 Feb 2026.