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SFM

Sphera Funds Management Portfolio holdings

AUM $630M
1-Year Est. Return 108.65%
This Fund
S&P 500
This Quarter Est. Return
-0.94%
1 Year Est. Return
+108.65%
3 Year Est. Return
+217.64%
5 Year Est. Return
+342.91%
10 Year Est. Return
+2,254.45%
AUM
$553M
AUM Growth
-$75.2M
Cap. Flow
-$19.5M
Cap. Flow %
-3.53%
Top 10 Hldgs %
31.54%
Holding
133
New
18
Increased
30
Reduced
36
Closed
26

Top Buys

Rank Stock Value
1
GOOG icon
Alphabet (Google) Class C
GOOG
+$7.68M
2
ANNX icon
Annexon
ANNX
+$7.65M
3
ORA icon
Ormat Technologies
ORA
+$6.1M
4
SNDX icon
Syndax Pharmaceuticals
SNDX
+$5.93M
5
SEDG icon
SolarEdge
SEDG
+$5.77M

Top Sells

Rank Stock Value
1
AAPL icon
Apple
AAPL
+$14.2M
2
TEVA icon
Teva Pharmaceuticals
TEVA
+$10.2M
3
AMZN icon
Amazon
AMZN
+$8.8M
4
S icon
SentinelOne
S
+$6.62M
5
NICE icon
Nice
NICE
+$6.39M

Sector Composition

Rank Sector Weight
1 Healthcare 73.33%
2 Technology 15.86%
3 Communication Services 3.88%
4 Consumer Discretionary 2.48%
5 Utilities 0.97%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
TEVA icon
1
Teva Pharmaceuticals
TEVA
$40.8B
$34.6M 6.25%
1,569,181
-561,035
-26% -$10.2M
BBIO icon
2
BridgeBio Pharma
BBIO
$15.7B
$24.8M 4.49%
905,279
+62,635
+7% +$1.62M
SNY icon
3
Sanofi
SNY
$103B
$18.5M 3.35%
384,515
-25,000
-6% -$1.27M
SNDX icon
4
Syndax Pharmaceuticals
SNDX
$1.69B
$18.3M 3.3%
1,381,241
+346,395
+33% +$5.93M
AZN icon
5
AstraZeneca
AZN
$263B
$14.7M 2.67%
112,530
+17,500
+18% +$2.45M
AMZN icon
6
Amazon
AMZN
$2.92T
$13.7M 2.48%
62,607
-43,000
-41% -$8.8M
NVMI
7
Nova
NVMI
$12.4B
$13.4M 2.43%
68,146
+16,186
+31% +$3.11M
META icon
8
Meta Platforms (Facebook)
META
$1.42T
$12.3M 2.22%
21,001
-8,315
-28% -$4.88M
SRPT icon
9
Sarepta Therapeutics
SRPT
$1.57B
$12M 2.17%
98,921
-26,925
-21% -$3.3M
CLDX icon
10
Celldex Therapeutics
CLDX
$2.99B
$12M 2.17%
474,103
+55,000
+13% +$1.49M
ELDN icon
11
Eledon Pharmaceuticals
ELDN
$261M
$10.5M 1.9%
2,551,619
+1,254,298
+97% +$4.94M
LLY icon
12
Eli Lilly
LLY
$1.02T
$10.2M 1.84%
13,190
– –
JNJ icon
13
Johnson & Johnson
JNJ
$618B
$10.1M 1.83%
69,831
– –
RARE icon
14
Ultragenyx Pharmaceutical
RARE
$2.45B
$9.62M 1.74%
228,776
+33,427
+17% +$1.66M
MSFT icon
15
Microsoft
MSFT
$3.45T
$9.41M 1.7%
22,327
-11,100
-33% -$4.73M
MRVL icon
16
Marvell Technology
MRVL
$168B
$8.68M 1.57%
78,611
-9,000
-10% -$836K
TSEM icon
17
Tower Semiconductor
TSEM
$24.8B
$8.56M 1.55%
166,149
-43,292
-21% -$2.03M
NVO
18
Novo Nordisk
NVO
$208B
$8.44M 1.53%
98,080
+20,000
+26% +$2.16M
WIX icon
19
WIX.com
WIX
$2.3B
$8.42M 1.52%
39,253
+5,000
+15% +$956K
GOOG icon
20
Alphabet (Google) Class C
GOOG
$4.36T
$8.28M 1.5%
+43,500
New +$7.68M
PHVS icon
21
Pharvaris
PHVS
$2.28B
$7.44M 1.35%
388,183
-51,109
-12% -$1.05M
NICE icon
22
Nice
NICE
$5.79B
$7.22M 1.3%
42,500
-35,861
-46% -$6.39M
CYTK icon
23
Cytokinetics
CYTK
$10.5B
$7.2M 1.3%
153,021
-72,000
-32% -$3.74M
PRAX icon
24
Praxis Precision Medicines
PRAX
$8.58B
$7.05M 1.27%
91,583
-60,724
-40% -$4.39M
CHKP icon
25
Check Point Software Technologies
CHKP
$13B
$6.65M 1.2%
35,635
-4,580
-11% -$863K
1
2 3 4 5

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Sphera Funds Management's Q4 2024 Portfolio in Review

As of Q4 2024, Sphera Funds Management held 133 positions worth $553M, down 12% from $628M the previous quarter. Its ten largest holdings account for 32% of the portfolio.

Sphera Funds Management withdrew a net $19.5M in Q4 2024, closing 26 positions and reducing 36 holdings. Its most notable exit was Apple, an estimated $14.2M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 73% of assets, up from 70% a quarter earlier, followed by Technology and Communication Services.

Against the trend, Sphera Funds Management opened a new position in Alphabet (Google) Class C worth $8.28M.

  • Sphera Funds Management's largest Q4 2024 buy was Alphabet (Google) Class C: 43,500 shares worth $8.28M.
  • Sphera Funds Management added most to Syndax Pharmaceuticals in Q4 2024, an estimated $5.93M increase.
  • Sphera Funds Management's biggest Q4 2024 reduction was Teva Pharmaceuticals, cutting an estimated $10.2M.
  • Sphera Funds Management fully exited Apple in Q4 2024, selling an estimated $14.2M.
  • Sphera Funds Management's ten largest holdings make up 32% of its $553M portfolio in Q4 2024.
  • Sphera Funds Management opened 18 new positions and closed 26 in Q4 2024.
  • Sphera Funds Management's portfolio value fell 12% quarter-over-quarter to $553M.

Based on Sphera Funds Management's 13F filing for Q4 2024, filed 14 Feb 2025.