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SFM

Sphera Funds Management Portfolio holdings

AUM $630M
1-Year Est. Return 108.65%
This Fund
S&P 500
This Quarter Est. Return
-0.94%
1 Year Est. Return
+108.65%
3 Year Est. Return
+217.64%
5 Year Est. Return
+342.91%
10 Year Est. Return
+2,254.45%
AUM
$553M
AUM Growth
-$75.2M
Cap. Flow
-$19.5M
Cap. Flow %
-3.53%
Top 10 Hldgs %
31.54%
Holding
133
New
18
Increased
30
Reduced
36
Closed
26

Top Buys

Rank Stock Value
1
GOOG icon
Alphabet (Google) Class C
GOOG
+$7.68M
2
ANNX icon
Annexon
ANNX
+$7.65M
3
ORA icon
Ormat Technologies
ORA
+$6.1M
4
SNDX icon
Syndax Pharmaceuticals
SNDX
+$5.93M
5
SEDG icon
SolarEdge
SEDG
+$5.77M

Top Sells

Rank Stock Value
1
AAPL icon
Apple
AAPL
+$14.2M
2
TEVA icon
Teva Pharmaceuticals
TEVA
+$10.2M
3
AMZN icon
Amazon
AMZN
+$8.8M
4
S icon
SentinelOne
S
+$6.62M
5
NICE icon
Nice
NICE
+$6.39M

Sector Composition

Rank Sector Weight
1 Healthcare 73.33%
2 Technology 15.86%
3 Communication Services 3.88%
4 Consumer Discretionary 2.48%
5 Utilities 0.97%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
AVGO icon
51
Broadcom
AVGO
$1.85T
$3.91M 0.71%
16,880
– –
SRRK icon
52
Scholar Rock
SRRK
$5.67B
$3.9M 0.7%
90,193
-76,673
-46% -$2.5M
TVTX icon
53
Travere Therapeutics
TVTX
$5.2B
$3.84M 0.7%
+220,700
New +$3.9M
ENGN icon
54
enGene Therapeutics
ENGN
$120M
$3.72M 0.67%
+560,000
New +$4.35M
SVRA icon
55
Savara
SVRA
$1.12B
$3.72M 0.67%
1,211,533
+648,426
+115% +$2.26M
ARWR icon
56
Arrowhead Research
ARWR
$11.9B
$3.71M 0.67%
+197,550
New +$4.07M
JANX icon
57
Janux Therapeutics
JANX
$925M
$3.66M 0.66%
+68,333
New +$3.61M
ACOG
58
Alpha Cognition
ACOG
$180M
$3.65M 0.66%
+620,000
New +$3.48M
SWTX
59
DELISTED
SpringWorks Therapeutics
SWTX
$3.61M 0.65%
+100,000
New +$3.49M
BIIB icon
60
Biogen
BIIB
$30B
$3.48M 0.63%
22,738
-1,717
-7% -$290K
ENPH icon
61
Enphase Energy
ENPH
$4.96B
$3.45M 0.62%
50,198
-14,026
-22% -$1.11M
RCKT icon
62
Rocket Pharmaceuticals
RCKT
$340M
$3.42M 0.62%
271,792
+40,000
+17% +$602K
INZY
63
DELISTED
Inozyme Pharma
INZY
$3.3M 0.6%
1,191,140
– –
CAMT icon
64
Camtek
CAMT
$6.18B
$2.93M 0.53%
36,287
– –
JSPR icon
65
Jasper Therapeutics
JSPR
$21M
$2.9M 0.52%
135,720
-53,550
-28% -$1.11M
CRVS icon
66
Corvus Pharmaceuticals
CRVS
$1.12B
$2.68M 0.48%
+500,491
New +$3.74M
CRGX
67
DELISTED
CARGO Therapeutics
CRGX
$2.59M 0.47%
179,674
-10,832
-6% -$197K
WDAY icon
68
Workday
WDAY
$39.6B
$2.58M 0.47%
10,000
+2,500
+33% +$639K
VIGL
69
DELISTED
Vigil Neuroscience
VIGL
$2.55M 0.46%
1,502,429
-145,175
-9% -$429K
NTR icon
70
Nutrien
NTR
$33.2B
$2.5M 0.45%
55,894
+15,164
+37% +$720K
CGEM icon
71
Cullinan Oncology
CGEM
$1.01B
$2.5M 0.45%
205,000
+19,129
+10% +$275K
PFE icon
72
Pfizer
PFE
$143B
$2.39M 0.43%
90,000
– –
VTGN icon
73
VistaGen Therapeutics
VTGN
$9.89M
$2.39M 0.43%
808,550
– –
CYTK icon
74
CALL
Cytokinetics
CYTK
$10.5B
$2.35M 0.43%
50,000
– –
MLYS icon
75
Mineralys Therapeutics
MLYS
$2.25B
$2.35M 0.42%
190,672
-81,800
-30% -$1.07M
1 2
3
4 5

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Sphera Funds Management's Q4 2024 Portfolio in Review

As of Q4 2024, Sphera Funds Management held 133 positions worth $553M, down 12% from $628M the previous quarter. Its ten largest holdings account for 32% of the portfolio.

Sphera Funds Management withdrew a net $19.5M in Q4 2024, closing 26 positions and reducing 36 holdings. Its most notable exit was Apple, an estimated $14.2M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 73% of assets, up from 70% a quarter earlier, followed by Technology and Communication Services.

Against the trend, Sphera Funds Management opened a new position in Alphabet (Google) Class C worth $8.28M.

  • Sphera Funds Management's largest Q4 2024 buy was Alphabet (Google) Class C: 43,500 shares worth $8.28M.
  • Sphera Funds Management added most to Syndax Pharmaceuticals in Q4 2024, an estimated $5.93M increase.
  • Sphera Funds Management's biggest Q4 2024 reduction was Teva Pharmaceuticals, cutting an estimated $10.2M.
  • Sphera Funds Management fully exited Apple in Q4 2024, selling an estimated $14.2M.
  • Sphera Funds Management's ten largest holdings make up 32% of its $553M portfolio in Q4 2024.
  • Sphera Funds Management opened 18 new positions and closed 26 in Q4 2024.
  • Sphera Funds Management's portfolio value fell 12% quarter-over-quarter to $553M.

Based on Sphera Funds Management's 13F filing for Q4 2024, filed 14 Feb 2025.