SI

Sofinnova Investments Portfolio holdings

AUM $1.47B
This Quarter Return
+22.43%
1 Year Return
+17.43%
3 Year Return
+337.79%
5 Year Return
+424.38%
10 Year Return
–
AUM
$1.61B
AUM Growth
+$1.61B
Cap. Flow
+$88.6M
Cap. Flow %
5.49%
Top 10 Hldgs %
65.91%
Holding
83
New
16
Increased
18
Reduced
12
Closed
15

Top Buys

1
AZN icon
AstraZeneca
AZN
$42.1M
2
HZNP
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
$15.6M
3
JAZZ icon
Jazz Pharmaceuticals
JAZZ
$13.6M
4
AMGN icon
Amgen
AMGN
$12.2M
5
ITCI
Intra-Cellular Therapies Inc.
ITCI
$11M

Top Sells

1
NXTC icon
NextCure
NXTC
$23.5M
2
LLY icon
Eli Lilly
LLY
$17.8M
3
MRK icon
Merck
MRK
$15.8M
4
INSM icon
Insmed
INSM
$10.2M
5
TGTX icon
TG Therapeutics
TGTX
$9.62M

Sector Composition

1 Healthcare 95.56%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
NTRA icon
1
Natera
NTRA
$23.1B
$309M 18.37% 3,100,560 – –
KRTX
2
DELISTED
Karuna Therapeutics, Inc. Common Stock
KRTX
$198M 11.81% 1,952,441 – –
ASND icon
3
Ascendis Pharma
ASND
$11.8B
$185M 11.02% 1,109,874 – –
YMAB icon
4
Y-mAbs Therapeutics
YMAB
$388M
$109M 6.47% 2,194,278 – –
UTHR icon
5
United Therapeutics
UTHR
$13.8B
$52.8M 3.14% 347,901 +26,942 +8% +$4.09M
CMPI
6
DELISTED
Checkmate Pharmaceuticals, Inc. Common Stock
CMPI
$52.6M 3.13% 3,606,707 – –
AZN icon
7
AstraZeneca
AZN
$248B
$42.1M 2.51% +842,600 New +$42.1M
INZY
8
DELISTED
Inozyme Pharma
INZY
$41.9M 2.49% 2,028,308 – –
AMGN icon
9
Amgen
AMGN
$155B
$37.9M 2.25% 164,663 +53,044 +48% +$12.2M
JAZZ icon
10
Jazz Pharmaceuticals
JAZZ
$7.75B
$35.1M 2.09% 212,911 +82,643 +63% +$13.6M
GRTX
11
DELISTED
Galera Therapeutics, Inc. Common Stock
GRTX
$31.5M 1.88% 3,083,712 – –
ABBV icon
12
AbbVie
ABBV
$372B
$31.5M 1.87% 293,596 -47,744 -14% -$5.12M
AKUS
13
DELISTED
Akouos, Inc. Common Stock
AKUS
$30M 1.79% 1,515,074 +1 +0% +$20
ITCI
14
DELISTED
Intra-Cellular Therapies Inc.
ITCI
$27M 1.61% 848,162 +344,607 +68% +$11M
NCNA
15
NuCana
NCNA
$6.09M
$25.1M 1.5% 5,599,999 – –
MRUS icon
16
Merus
MRUS
$4.98B
$23M 1.37% 1,311,039 – –
PTCT icon
17
PTC Therapeutics
PTCT
$3.92B
$19.3M 1.15% 316,478 -88,674 -22% -$5.41M
RETA
18
DELISTED
Reata Pharmaceuticals, Inc. Class A Common Stock
RETA
$18.4M 1.1% 148,937 +80,322 +117% +$9.93M
ATHA icon
19
Athira Pharma
ATHA
$15.3M
$17.4M 1.04% 509,168 – –
OTIC
20
DELISTED
Otonomy, Inc.
OTIC
$17M 1.01% 2,620,668 +509,072 +24% +$3.29M
HZNP
21
DELISTED
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
$15.6M 0.93% +213,390 New +$15.6M
BMRN icon
22
BioMarin Pharmaceuticals
BMRN
$11.2B
$14.4M 0.86% 164,545 -94,108 -36% -$8.25M
ACRS icon
23
Aclaris Therapeutics
ACRS
$209M
$12.4M 0.74% 1,911,573 – –
RGNX icon
24
Regenxbio
RGNX
$451M
$12.3M 0.73% 271,114 +211,607 +356% +$9.6M
GWPH
25
DELISTED
GW Pharmaceuticals Plc American Depositary Shares
GWPH
$11.6M 0.69% 100,762 +17,818 +21% +$2.06M
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