SI

Sofinnova Investments Portfolio holdings

AUM $1.47B
This Quarter Return
+44.07%
1 Year Return
+17.43%
3 Year Return
+337.79%
5 Year Return
+424.38%
10 Year Return
–
AUM
$980M
AUM Growth
+$980M
Cap. Flow
-$118M
Cap. Flow %
-12%
Top 10 Hldgs %
66.15%
Holding
75
New
12
Increased
8
Reduced
18
Closed
12

Top Buys

1
AGN
Allergan plc
AGN
$13M
2
NVO icon
Novo Nordisk
NVO
$13M
3
ALNY icon
Alnylam Pharmaceuticals
ALNY
$9.96M
4
HALO icon
Halozyme
HALO
$6.46M
5
BPMC
Blueprint Medicines
BPMC
$5.75M

Top Sells

1
ASND icon
Ascendis Pharma
ASND
$58.9M
2
PDSB icon
PDS Biotechnology
PDSB
$20M
3
SNY icon
Sanofi
SNY
$14.2M
4
GILD icon
Gilead Sciences
GILD
$13.3M
5
INCY icon
Incyte
INCY
$11.6M

Sector Composition

1 Healthcare 88.82%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
ASND icon
1
Ascendis Pharma
ASND
$11.8B
$118M 11.33% 998,538 -500,000 -33% -$58.9M
AMRN
2
Amarin Corp
AMRN
$311M
$108M 10.42% 5,208,305 – –
PRNB
3
DELISTED
Principia Biopharma Inc. Common Stock
PRNB
$69.3M 6.68% 2,038,208 – –
NTRA icon
4
Natera
NTRA
$23.1B
$63.9M 6.16% 3,100,560 – –
OBSV
5
DELISTED
ObsEva SA Ordinary Shares
OBSV
$60.7M 5.86% 4,749,623 – –
YMAB icon
6
Y-mAbs Therapeutics
YMAB
$388M
$55.2M 5.32% 2,104,278 – –
ONCE
7
DELISTED
Spark Therapeutics, Inc. Common Stock
ONCE
$54.8M 5.28% 481,270 – –
CHRS icon
8
Coherus Oncology, Inc. Common Stock
CHRS
$135M
$39.1M 3.77% 2,868,221 – –
NCNA
9
NuCana
NCNA
$6.09M
$38.5M 3.71% 2,266,666 – –
BOLD
10
DELISTED
Audentes Therapeutics, Inc
BOLD
$36.4M 3.51% 933,640 – –
MRUS icon
11
Merus
MRUS
$4.98B
$29M 2.79% 1,961,039 – –
KNSA icon
12
Kiniksa Pharmaceuticals
KNSA
$2.48B
$16.7M 1.61% 922,700 – –
ITRM icon
13
Iterum Therapeutics
ITRM
$30.2M
$13.7M 1.32% 1,726,514 – –
AGN
14
DELISTED
Allergan plc
AGN
$13M 1.25% +88,665 New +$13M
NVO icon
15
Novo Nordisk
NVO
$251B
$13M 1.25% +247,734 New +$13M
ACRS icon
16
Aclaris Therapeutics
ACRS
$209M
$11.5M 1.1% 1,911,573 – –
AZN icon
17
AstraZeneca
AZN
$248B
$10.6M 1.02% 261,577 -54,751 -17% -$2.21M
ALNY icon
18
Alnylam Pharmaceuticals
ALNY
$58.5B
$9.96M 0.96% +106,616 New +$9.96M
NBIX icon
19
Neurocrine Biosciences
NBIX
$13.8B
$9.9M 0.95% 112,406 +50,906 +83% +$4.49M
MGNX icon
20
MacroGenics
MGNX
$112M
$9.42M 0.91% 523,756 +190,835 +57% +$3.43M
CHMA
21
DELISTED
Chiasma, Inc. Common Stock
CHMA
$8.48M 0.82% 1,630,221 – –
ETTX
22
DELISTED
Entasis Therapeutics Holdings Inc.
ETTX
$7.97M 0.77% 1,180,178 – –
FOLD icon
23
Amicus Therapeutics
FOLD
$2.34B
$7.94M 0.77% 584,108 -90,528 -13% -$1.23M
ANAB icon
24
AnaptysBio
ANAB
$569M
$7.16M 0.69% 97,948 +72,928 +291% +$5.33M
DERM
25
DELISTED
Dermira, Inc.
DERM
$6.55M 0.63% 483,640 -58,584 -11% -$794K
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