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Sofinnova Investments Portfolio holdings

AUM $2.63B
1-Year Est. Return 117.41%
This Fund
S&P 500
This Quarter Est. Return
-4.77%
1 Year Est. Return
+117.41%
3 Year Est. Return
+428.82%
5 Year Est. Return
+748.21%
10 Year Est. Return
–
AUM
$1.53B
AUM Growth
+$158M
Cap. Flow
+$341M
Cap. Flow %
22.28%
Top 10 Hldgs %
52.34%
Holding
81
New
20
Increased
20
Reduced
13
Closed
17

Top Buys

Rank Stock Value
1
SYK icon
Stryker
SYK
+$69.5M
2
MDT icon
Medtronic
MDT
+$50.4M
3
IDYA icon
IDEAYA Biosciences
IDYA
+$33.1M
4
LLY icon
Eli Lilly
LLY
+$32M
5
PTCT icon
PTC Therapeutics
PTCT
+$28.9M

Top Sells

Rank Stock Value
1
ABBV icon
AbbVie
ABBV
+$63.9M
2
AZN icon
AstraZeneca
AZN
+$42.7M
3
GILD icon
Gilead Sciences
GILD
+$36.7M
4
AXSM icon
Axsome Therapeutics
AXSM
+$36M
5
BSX icon
Boston Scientific
BSX
+$31M

Sector Composition

Rank Sector Weight
1 Healthcare 86.61%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ICUI icon
76
ICU Medical
ICUI
$4.14B
– –
-5,000
Closed -$776K
JANX icon
77
Janux Therapeutics
JANX
$899M
– –
-253,262
Closed -$13.6M
KROS icon
78
Keros Therapeutics
KROS
$198M
– –
-95,375
Closed -$1.51M
LUNG icon
79
Pulmonx
LUNG
$52.8M
– –
-61,326
Closed -$416K
TVTX icon
80
Travere Therapeutics
TVTX
$5.12B
– –
-32,616
Closed -$568K
NARI
81
DELISTED
Inari Medical, Inc. Common Stock
NARI
– –
-180,456
Closed -$9.21M
1 2 3
4

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Sofinnova Investments's Q1 2025 Portfolio in Review

As of Q1 2025, Sofinnova Investments held 81 positions worth $1.53B, up 12% from $1.37B the previous quarter. Its ten largest holdings account for 52% of the portfolio.

Sofinnova Investments deployed $341M of net new capital in Q1 2025, opening 20 new positions and adding to 20 existing holdings. Its largest new stake was Medtronic: 562,992 shares worth $50.6M.

By sector, the portfolio is most concentrated in Healthcare at 87% of assets, down from 99% a quarter earlier.

On the sell side, the largest reduction was Gilead Sciences, an estimated $36.7M trimmed.

  • Sofinnova Investments's largest Q1 2025 buy was Medtronic: 562,992 shares worth $50.6M.
  • Sofinnova Investments added most to Stryker in Q1 2025, an estimated $69.5M increase.
  • Sofinnova Investments's biggest Q1 2025 reduction was Gilead Sciences, cutting an estimated $36.7M.
  • Sofinnova Investments fully exited AbbVie in Q1 2025, selling an estimated $63.9M.
  • Sofinnova Investments's ten largest holdings make up 52% of its $1.53B portfolio in Q1 2025.
  • Sofinnova Investments opened 20 new positions and closed 17 in Q1 2025.
  • Sofinnova Investments's portfolio value rose 12% quarter-over-quarter to $1.53B.

Based on Sofinnova Investments's 13F filing for Q1 2025, filed 15 May 2025.