SI

Sofinnova Investments Portfolio holdings

AUM $1.47B
This Quarter Return
-3.68%
1 Year Return
+17.43%
3 Year Return
+337.79%
5 Year Return
+424.38%
10 Year Return
–
AUM
$1.12B
AUM Growth
+$1.12B
Cap. Flow
+$30.4M
Cap. Flow %
2.7%
Top 10 Hldgs %
66.5%
Holding
70
New
11
Increased
15
Reduced
11
Closed
12

Top Buys

1
MRK icon
Merck
MRK
$32.9M
2
NVO icon
Novo Nordisk
NVO
$30.5M
3
IRTC icon
iRhythm Technologies
IRTC
$15.4M
4
KRTX
Karuna Therapeutics, Inc. Common Stock
KRTX
$15.2M
5
SNY icon
Sanofi
SNY
$14.1M

Top Sells

1
UTHR icon
United Therapeutics
UTHR
$21.9M
2
ZTS icon
Zoetis
ZTS
$20.1M
3
SRRA
Sierra Oncology, Inc. Common Stock
SRRA
$18.3M
4
GH icon
Guardant Health
GH
$15.9M
5
AZN icon
AstraZeneca
AZN
$15.7M

Sector Composition

1 Healthcare 98.44%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
FUSN
51
DELISTED
Fusion Pharmaceuticals Inc. Common Shares
FUSN
$194K 0.02%
78,066
– –
INSM icon
52
Insmed
INSM
$30.7B
$145K 0.01%
7,370
+2,002
+37% +$39.4K
PFE icon
53
Pfizer
PFE
$142B
– –
-49,378
Closed -$2.56M
PODD icon
54
Insulet
PODD
$24.3B
– –
-1,066
Closed -$284K
PTCT icon
55
PTC Therapeutics
PTCT
$4.16B
– –
-3,480
Closed -$130K
PTGX icon
56
Protagonist Therapeutics
PTGX
$3.66B
– –
-547,441
Closed -$13M
QQQ icon
57
Invesco QQQ Trust
QQQ
$361B
– –
0
– –
XBI icon
58
SPDR S&P Biotech ETF
XBI
$5.25B
– –
0
– –
XLV icon
59
Health Care Select Sector SPDR Fund
XLV
$33.9B
– –
0
– –
ZTS icon
60
Zoetis
ZTS
$67.8B
– –
-106,574
Closed -$20.1M
ICPT
61
DELISTED
Intercept Pharmaceuticals, Inc.
ICPT
– –
0
– –
SRRA
62
DELISTED
Sierra Oncology, Inc. Common Stock
SRRA
– –
-572,297
Closed -$18.3M
BCYC
63
Bicycle Therapeutics
BCYC
$499M
– –
-163,559
Closed -$7.18M
FULC icon
64
Fulcrum Therapeutics
FULC
$347M
– –
-229,509
Closed -$5.43M
GH icon
65
Guardant Health
GH
$8.29B
– –
-239,995
Closed -$15.9M
HRTX icon
66
Heron Therapeutics
HRTX
$202M
– –
-11,060
Closed -$63K
INKT icon
67
MiNK Therapeutics
INKT
$62.7M
– –
-331,002
Closed -$745K
IWM icon
68
iShares Russell 2000 ETF
IWM
$66.6B
– –
0
– –
CMPI
69
DELISTED
Checkmate Pharmaceuticals, Inc. Common Stock
CMPI
– –
-3,606,707
Closed -$11.5M
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