SI

Sofinnova Investments Portfolio holdings

AUM $1.47B
This Quarter Return
+3.25%
1 Year Return
+17.43%
3 Year Return
+337.79%
5 Year Return
+424.38%
10 Year Return
–
AUM
$1.56B
AUM Growth
+$1.56B
Cap. Flow
-$70.3M
Cap. Flow %
-4.51%
Top 10 Hldgs %
66.12%
Holding
83
New
13
Increased
14
Reduced
20
Closed
13

Top Buys

1
ABBV icon
AbbVie
ABBV
$29.4M
2
BPMC
Blueprint Medicines
BPMC
$18.7M
3
HZNP
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
$17.3M
4
ZTS icon
Zoetis
ZTS
$14.8M
5
ZYME icon
Zymeworks
ZYME
$11.9M

Top Sells

1
XLRN
Acceleron Pharma Inc.
XLRN
$33.4M
2
BIIB icon
Biogen
BIIB
$21.9M
3
NBIX icon
Neurocrine Biosciences
NBIX
$19.8M
4
PODD icon
Insulet
PODD
$19.2M
5
VRTX icon
Vertex Pharmaceuticals
VRTX
$17.8M

Sector Composition

1 Healthcare 98.91%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
SRRA
51
DELISTED
Sierra Oncology, Inc. Common Stock
SRRA
$4.53M 0.27%
206,564
+204,064
+8,163% +$4.47M
CYT
52
DELISTED
Cyteir Therapeutics, Inc. Common Stock
CYT
$4.32M 0.26%
246,321
-18,679
-7% -$328K
QURE icon
53
uniQure
QURE
$954M
$2.52M 0.15%
78,742
-245,561
-76% -$7.86M
PDSB icon
54
PDS Biotechnology
PDSB
$60.6M
$2.13M 0.13%
142,635
– –
ALGS icon
55
Aligos Therapeutics
ALGS
$75.1M
$1.93M 0.11%
124,342
-39,709
-24% -$616K
MRNS
56
DELISTED
Marinus Pharmaceuticals, Inc
MRNS
$1.9M 0.11%
166,711
-179,449
-52% -$2.04M
SYBX icon
57
Synlogic
SYBX
$17.4M
$1.75M 0.1%
574,972
– –
FULC icon
58
Fulcrum Therapeutics
FULC
$353M
$1.44M 0.09%
+51,006
New +$1.44M
FUSN
59
DELISTED
Fusion Pharmaceuticals Inc. Common Shares
FUSN
$618K 0.04%
+78,066
New +$618K
PODD icon
60
Insulet
PODD
$24.2B
$303K 0.02%
1,066
-67,434
-98% -$19.2M
OTIC
61
DELISTED
Otonomy, Inc.
OTIC
– –
-1,251,256
Closed -$2.79M
TCRR
62
DELISTED
TCR2 Therapeutics Inc. Common Stock
TCRR
– –
-296,282
Closed -$4.86M
ICPT
63
DELISTED
Intercept Pharmaceuticals, Inc.
ICPT
– –
0
– –
VRTX icon
64
Vertex Pharmaceuticals
VRTX
$102B
– –
-88,214
Closed -$17.8M
SVRA icon
65
Savara
SVRA
$591M
– –
-1,278,424
Closed -$2.17M
REGN icon
66
Regeneron Pharmaceuticals
REGN
$59.8B
– –
0
– –
OEF icon
67
iShares S&P 100 ETF
OEF
$22.1B
– –
0
– –
NVCR icon
68
NovoCure
NVCR
$1.35B
– –
0
– –
NBIX icon
69
Neurocrine Biosciences
NBIX
$13.5B
– –
-203,200
Closed -$19.8M
MRK icon
70
Merck
MRK
$210B
– –
0
– –
MIRM icon
71
Mirum Pharmaceuticals
MIRM
$3.75B
– –
-259,465
Closed -$4.49M
ACAD icon
72
Acadia Pharmaceuticals
ACAD
$4.34B
– –
0
– –
REPL icon
73
Replimune Group
REPL
$460M
– –
-71,661
Closed -$2.75M
MGNX icon
74
MacroGenics
MGNX
$121M
– –
-234,504
Closed -$6.3M
FGEN icon
75
FibroGen
FGEN
$48.4M
– –
0
– –
1 2
3
4