SI

Sofinnova Investments Portfolio holdings

AUM $1.47B
This Quarter Return
-11.36%
1 Year Return
+17.43%
3 Year Return
+337.79%
5 Year Return
+424.38%
10 Year Return
–
AUM
$1.05B
AUM Growth
+$1.05B
Cap. Flow
-$67.4M
Cap. Flow %
-6.4%
Top 10 Hldgs %
68.08%
Holding
76
New
16
Increased
8
Reduced
12
Closed
14

Top Buys

1
ALXN
Alexion Pharmaceuticals Inc
ALXN
$27.6M
2
MRK icon
Merck
MRK
$17.2M
3
ALGN icon
Align Technology
ALGN
$8.09M
4
MIRM icon
Mirum Pharmaceuticals
MIRM
$5.86M
5
PBYI icon
Puma Biotechnology
PBYI
$5.39M

Top Sells

1
REGN icon
Regeneron Pharmaceuticals
REGN
$18.8M
2
BMRN icon
BioMarin Pharmaceuticals
BMRN
$17.1M
3
MRTX
Mirati Therapeutics, Inc. Common Stock
MRTX
$14M
4
FATE icon
Fate Therapeutics
FATE
$13.3M
5
MGNX icon
MacroGenics
MGNX
$12.8M

Sector Composition

1 Healthcare 98.07%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
APLS icon
51
Apellis Pharmaceuticals
APLS
$3.51B
$1.33M 0.12%
49,580
– –
MRSN icon
52
Mersana Therapeutics
MRSN
$34.8M
$1.31M 0.12%
+225,000
New +$1.31M
SYBX icon
53
Synlogic
SYBX
$17.4M
$989K 0.09%
574,972
– –
ZGNX
54
DELISTED
Zogenix, Inc.
ZGNX
$816K 0.08%
+32,983
New +$816K
FATE icon
55
Fate Therapeutics
FATE
$115M
$812K 0.08%
36,564
-598,579
-94% -$13.3M
ITCI
56
DELISTED
Intra-Cellular Therapies Inc.
ITCI
$800K 0.07%
+52,005
New +$800K
PDSB icon
57
PDS Biotechnology
PDSB
$60.6M
$104K 0.01%
142,635
– –
MDCO
58
DELISTED
Medicines Co
MDCO
– –
0
– –
ARQL
59
DELISTED
Arqule Inc
ARQL
– –
-387,469
Closed -$7.73M
DERM
60
DELISTED
Dermira, Inc.
DERM
– –
-545,466
Closed -$8.27M
FOMX
61
DELISTED
Foamix Pharmaceuticals Ltd. Ordinary Shares
FOMX
– –
-1,162,176
Closed -$3.87M
DRNA
62
DELISTED
Dicerna Pharmaceuticals, Inc.
DRNA
– –
-159,512
Closed -$3.51M
SGEN
63
DELISTED
Seagen Inc. Common Stock
SGEN
– –
-50,000
Closed -$5.71M
MRTX
64
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
– –
-108,383
Closed -$14M
ORTX
65
DELISTED
Orchard Therapeutics plc American Depositary Shares
ORTX
– –
-283,406
Closed -$3.9M
XBIT icon
66
XBiotech
XBIT
$90.9M
– –
-240,995
Closed -$4.5M
RYTM icon
67
Rhythm Pharmaceuticals
RYTM
$6.75B
– –
-21,319
Closed -$489K
REGN icon
68
Regeneron Pharmaceuticals
REGN
$59.8B
– –
-50,086
Closed -$18.8M
MGNX icon
69
MacroGenics
MGNX
$121M
– –
-1,173,882
Closed -$12.8M
IOVA icon
70
Iovance Biotherapeutics
IOVA
$800M
– –
0
– –
HALO icon
71
Halozyme
HALO
$8.75B
– –
-72,481
Closed -$1.29M
GILD icon
72
Gilead Sciences
GILD
$140B
– –
0
– –
APLT icon
73
Applied Therapeutics
APLT
$73.7M
– –
-134,825
Closed -$3.68M
ALNY icon
74
Alnylam Pharmaceuticals
ALNY
$58.6B
– –
0
– –
FTSV
75
DELISTED
Forty Seven, Inc. Common Stock
FTSV
– –
-138,643
Closed -$5.46M
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