SI

Sofinnova Investments Portfolio holdings

AUM $1.47B
1-Year Return 17.43%
This Quarter Return
-20.94%
1 Year Return
+17.43%
3 Year Return
+337.79%
5 Year Return
+424.38%
10 Year Return
–
AUM
$803M
AUM Growth
-$311M
Cap. Flow
-$45.5M
Cap. Flow %
-5.67%
Top 10 Hldgs %
60.78%
Holding
77
New
17
Increased
17
Reduced
12
Closed
18

Top Buys

1
NCNA
NuCana
NCNA
$23.2M
2
GILD icon
Gilead Sciences
GILD
$13.3M
3
INCY icon
Incyte
INCY
$12M
4
BMRN icon
BioMarin Pharmaceuticals
BMRN
$12M
5
RETA
Reata Pharmaceuticals, Inc. Class A Common Stock
RETA
$8.86M

Top Sells

1
ASND icon
Ascendis Pharma
ASND
$61.5M
2
AGN
Allergan plc
AGN
$18.3M
3
ALXN
Alexion Pharmaceuticals Inc
ALXN
$9.09M
4
EXEL icon
Exelixis
EXEL
$7.15M
5
ADMS
Adamas Pharmaceuticals, Inc.
ADMS
$6.92M

Sector Composition

1 Healthcare 91.28%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
OTIC
51
DELISTED
Otonomy, Inc.
OTIC
$1.89M 0.24%
1,023,865
+36,087
+4% +$66.8K
ANAB icon
52
AnaptysBio
ANAB
$590M
$1.6M 0.2%
25,020
-44,595
-64% -$2.84M
SNDX icon
53
Syndax Pharmaceuticals
SNDX
$1.39B
$1.56M 0.19%
350,110
+176,998
+102% +$788K
HSTO
54
DELISTED
Histogen Inc. Common Stock
HSTO
$1.1M 0.14%
3,191
+496
+18% +$172K
PDSB icon
55
PDS Biotechnology
PDSB
$56.9M
$916K 0.11%
142,636
– –
PCRX icon
56
Pacira BioSciences
PCRX
$1.2B
$731K 0.09%
+16,994
New +$731K
APLS icon
57
Apellis Pharmaceuticals
APLS
$3.62B
$654K 0.08%
49,580
-500,000
-91% -$6.6M
ADAP
58
Adaptimmune Therapeutics
ADAP
$13.5M
– –
-89,919
Closed -$1.22M
BPMC
59
DELISTED
Blueprint Medicines
BPMC
– –
-51,339
Closed -$4.01M
CLSD icon
60
Clearside Biomedical
CLSD
$27.5M
– –
-606,914
Closed -$3.73M
CPRX icon
61
Catalyst Pharmaceutical
CPRX
$2.42B
– –
-1,549,552
Closed -$5.86M
ESPR icon
62
Esperion Therapeutics
ESPR
$510M
– –
-36,599
Closed -$1.62M
EXEL icon
63
Exelixis
EXEL
$10.1B
– –
-403,594
Closed -$7.15M
KURA icon
64
Kura Oncology
KURA
$706M
– –
-247,385
Closed -$4.33M
OCGN icon
65
Ocugen
OCGN
$322M
– –
-34,617
Closed -$1.13M
RYTM icon
66
Rhythm Pharmaceuticals
RYTM
$6.95B
– –
-159,302
Closed -$4.65M
CYTO
67
DELISTED
Altamira Therapeutics Ltd. Common Shares 0.01 SF (Bermuda)
CYTO
– –
-18
Closed –
KDNY
68
DELISTED
Chinook Therapeutics, Inc. Common Stock
KDNY
– –
-37,916
Closed -$1.39M
FSTX
69
DELISTED
F-star Therapeutics, Inc. Common Stock
FSTX
– –
-47,412
Closed -$2.29M
ADMS
70
DELISTED
Adamas Pharmaceuticals, Inc.
ADMS
– –
-345,756
Closed -$6.92M
ALXN
71
DELISTED
Alexion Pharmaceuticals Inc
ALXN
– –
-65,360
Closed -$9.09M
AGN
72
DELISTED
Allergan plc
AGN
– –
-96,021
Closed -$18.3M
ARQL
73
DELISTED
Arqule Inc
ARQL
– –
-386,271
Closed -$2.19M
OMED
74
DELISTED
OncoMed Pharmaceuticals, Inc.
OMED
– –
-395,744
Closed -$839K
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