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SI

Sofinnova Investments Portfolio holdings

AUM $2B
1-Year Est. Return 127.65%
This Fund
S&P 500
This Quarter Est. Return
1 Year Est. Return
+127.65%
3 Year Est. Return
5 Year Est. Return
10 Year Est. Return
AUM
$2B
AUM Growth
-$323M
Cap. Flow
Cap. Flow %
Top 10 Hldgs %
Holding
84
New
Increased
Reduced
Closed

Top Buys

1
+$69M
2
+$42.3M
3
+$34.6M
4
ALC icon
Alcon
ALC
+$31.7M
5
INSM icon
Insmed
INSM
+$29.1M

Top Sells

1
+$191M
2
+$74.6M
3
+$72.6M
4
ISRG icon
Intuitive Surgical
ISRG
+$71.9M
5
LLY icon
Eli Lilly
LLY
+$66.3M

Sector Composition

1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ESTA icon
51
Establishment Labs
ESTA
$2.34B
$1.93M 0.1%
33,930
+5,564
ACAD icon
52
Acadia Pharmaceuticals
ACAD
$3.64B
$1.75M 0.09%
78,551
+12,984
TENX icon
53
Tenax Therapeutics
TENX
$280M
$1.67M 0.08%
+104,400
JBIO
54
Jade Biosciences
JBIO
$929M
$1.51M 0.08%
107,391
WVE icon
55
Wave Life Sciences
WVE
$1.09B
$1.37M 0.07%
189,253
+31,071
SEPN
56
Septerna Inc
SEPN
$1.37B
$1.14M 0.06%
+47,506
OKUR
57
OnKure Therapeutics
OKUR
$169M
$587K 0.03%
+141,700
BOLT icon
58
Bolt Biotherapeutics
BOLT
$8.51M
$556K 0.03%
137,721
SLNO
59
DELISTED
Soleno Therapeutics
SLNO
$492K 0.02%
14,689
+2,275
IMA
60
ImageneBio Inc
IMA
$62.1M
$159K 0.01%
31,884
ZYME icon
61
Zymeworks
ZYME
$1.68B
$40.3K ﹤0.01%
+1,610
AMLX icon
62
Amylyx Pharmaceuticals
AMLX
$1.5B
– –
-527,099
CNTA
63
Centessa Pharmaceuticals
CNTA
$6.14B
– –
-1,104,274
EXAS
64
DELISTED
Exact Sciences
EXAS
– –
-101,443
EXEL icon
65
Exelixis
EXEL
$13.2B
– –
0
LQDA icon
66
Liquidia Corp
LQDA
$5.8B
– –
0
MASI icon
67
Masimo
MASI
$9.42B
– –
-46,201
VRTX icon
68
Vertex Pharmaceuticals
VRTX
$111B
– –
-164,594
XBI icon
69
State Street SPDR S&P Biotech ETF
XBI
$7.79B
– –
0
ABBV icon
70
AbbVie
ABBV
$397B
– –
-317,783
APGE icon
71
Apogee Therapeutics
APGE
$6.24B
– –
-534,845
CDTX
72
DELISTED
Cidara Therapeutics
CDTX
– –
-180,265
GEHC icon
73
GE HealthCare
GEHC
$29B
– –
-160,876
GKOS icon
74
Glaukos
GKOS
$7.19B
– –
-288,128
IBB icon
75
iShares Biotechnology ETF
IBB
$7.67B
– –
0
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