SI

Sofinnova Investments Portfolio holdings

AUM $1.47B
1-Year Return 17.43%
This Quarter Return
+1.68%
1 Year Return
+17.43%
3 Year Return
+337.79%
5 Year Return
+424.38%
10 Year Return
–
AUM
$1.06B
AUM Growth
+$75.8M
Cap. Flow
+$109M
Cap. Flow %
10.32%
Top 10 Hldgs %
61.71%
Holding
84
New
16
Increased
22
Reduced
6
Closed
13

Top Buys

1
NXTC icon
NextCure
NXTC
$37.8M
2
KRTX
Karuna Therapeutics, Inc. Common Stock
KRTX
$34.6M
3
PTCT icon
PTC Therapeutics
PTCT
$16.6M
4
ASND icon
Ascendis Pharma
ASND
$11.7M
5
XLRN
Acceleron Pharma Inc.
XLRN
$9.9M

Top Sells

1
CHRS icon
Coherus Oncology, Inc. Common Stock
CHRS
$17.1M
2
AZN icon
AstraZeneca
AZN
$10.6M
3
ANAB icon
AnaptysBio
ANAB
$7.16M
4
XNCR icon
Xencor
XNCR
$6.52M
5
BHVN
Biohaven Pharmaceutical Holding Company Ltd.
BHVN
$6.43M

Sector Composition

1 Healthcare 91.3%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
MGNX icon
26
MacroGenics
MGNX
$126M
$9.34M 0.86%
550,443
+26,687
+5% +$453K
VRTX icon
27
Vertex Pharmaceuticals
VRTX
$102B
$9.23M 0.85%
+50,301
New +$9.23M
BMY icon
28
Bristol-Myers Squibb
BMY
$95.5B
$7.88M 0.72%
+173,849
New +$7.88M
ETTX
29
DELISTED
Entasis Therapeutics Holdings Inc.
ETTX
$7.61M 0.7%
1,180,178
– –
FOLD icon
30
Amicus Therapeutics
FOLD
$2.45B
$7.28M 0.67%
583,309
-799
-0.1% -$9.97K
BMRN icon
31
BioMarin Pharmaceuticals
BMRN
$10.8B
$7.27M 0.67%
84,896
+66,402
+359% +$5.69M
DERM
32
DELISTED
Dermira, Inc.
DERM
$6.31M 0.58%
659,882
+176,242
+36% +$1.69M
INCY icon
33
Incyte
INCY
$16.7B
$5.91M 0.54%
69,612
+16,515
+31% +$1.4M
SYBX icon
34
Synlogic
SYBX
$17M
$5.23M 0.48%
38,331
– –
ORTX
35
DELISTED
Orchard Therapeutics plc American Depositary Shares
ORTX
$5.11M 0.47%
36,547
+8,939
+32% +$1.25M
KDMN
36
DELISTED
Kadmon Holdings, Inc.
KDMN
$4.54M 0.42%
2,204,202
+532,432
+32% +$1.1M
ACRS icon
37
Aclaris Therapeutics
ACRS
$221M
$4.19M 0.38%
1,911,573
– –
ACAD icon
38
Acadia Pharmaceuticals
ACAD
$4.32B
$4.16M 0.38%
+155,576
New +$4.16M
ZYME icon
39
Zymeworks
ZYME
$1.07B
$4.14M 0.38%
+188,057
New +$4.14M
AKBA icon
40
Akebia Therapeutics
AKBA
$809M
$4.11M 0.38%
848,356
+331,595
+64% +$1.6M
OTIC
41
DELISTED
Otonomy, Inc.
OTIC
$3.68M 0.34%
1,337,568
+313,703
+31% +$863K
ARQL
42
DELISTED
Arqule Inc
ARQL
$3.1M 0.29%
281,857
-73,868
-21% -$813K
FOMX
43
DELISTED
Foamix Pharmaceuticals Ltd. Ordinary Shares
FOMX
$2.66M 0.24%
1,115,810
+283,517
+34% +$675K
XBIT icon
44
XBiotech
XBIT
$89.6M
$2.52M 0.23%
331,811
+70,420
+27% +$534K
SNDX icon
45
Syndax Pharmaceuticals
SNDX
$1.38B
$2.26M 0.21%
242,729
+29,370
+14% +$273K
ADVM icon
46
Adverum Biotechnologies
ADVM
$66.3M
$2.23M 0.2%
18,706
+2,782
+17% +$331K
ABBV icon
47
AbbVie
ABBV
$375B
$2.1M 0.19%
+28,911
New +$2.1M
CALA
48
DELISTED
Calithera Biosciences, Inc
CALA
$2.07M 0.19%
+26,492
New +$2.07M
ALNY icon
49
Alnylam Pharmaceuticals
ALNY
$59.1B
$2.02M 0.19%
27,792
-78,824
-74% -$5.72M
RVLP
50
DELISTED
RVL Pharmaceuticals plc Ordinary Shares
RVLP
$2M 0.18%
525,198
+272,109
+108% +$1.03M
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