Renaissance Technologies’s Clearside Biomedical CLSD Stock Holding History

Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake
Trade Value Portfolio Weight Portfolio Position
2025
Q4
Sell
-25,247
Closed -$100K 3296
2025
Q3
$100K Sell
25,247
-7,859
-24% -$53.5K ﹤0.01% 3248
2025
Q2
$397K Sell
33,106
-3,861
-10% -$47.9K ﹤0.01% 2949
2025
Q1
$509K Sell
36,967
-11,152
-23% -$160K ﹤0.01% 2738
2024
Q4
$686K Sell
48,119
-1,540
-3% -$25.3K ﹤0.01% 2692
2024
Q3
$946K Buy
49,659
+10,813
+28% +$185K ﹤0.01% 2479
2024
Q2
$757K Buy
38,846
+2,393
+7% +$46.2K ﹤0.01% 2480
2024
Q1
$837K Buy
36,453
+10,807
+42% +$233K ﹤0.01% 2587
2023
Q4
$450K Buy
25,646
+7,427
+41% +$106K ﹤0.01% 2829
2023
Q3
$238K Sell
18,219
-4,227
-19% -$64K ﹤0.01% 3029
2023
Q2
$377K Sell
22,446
-8,180
-27% -$141K ﹤0.01% 3020
2023
Q1
$478K Sell
30,626
-8,533
-22% -$166K ﹤0.01% 2913
2022
Q4
$658K Sell
39,159
-4,740
-11% -$85.4K ﹤0.01% 2778
2022
Q3
$744K Sell
43,899
-9,954
-18% -$218K ﹤0.01% 2676
2022
Q2
$1.19M Sell
53,853
-3,810
-7% -$92.5K ﹤0.01% 2595
2022
Q1
$1.98M Buy
57,663
+29,049
+102% +$869K ﹤0.01% 2240
2021
Q4
$1.18M Buy
28,614
+21,848
+323% +$1.42M ﹤0.01% 2524
2021
Q3
$609K Buy
6,766
+2,060
+44% +$182K ﹤0.01% 2799
2021
Q2
$344K Sell
4,706
-32,927
-87% -$1.53M ﹤0.01% 3099
2021
Q1
$1.39M Buy
37,633
+7,007
+23% +$352K ﹤0.01% 2440
2020
Q4
$1.26M Sell
30,626
-4,640
-13% -$120K ﹤0.01% 2386
2020
Q3
$815K Sell
35,266
-18,830
-35% -$487K ﹤0.01% 2613
2020
Q2
$1.53M Buy
54,096
+27,903
+107% +$822K ﹤0.01% 2328
2020
Q1
$668K Buy
26,193
+20,280
+343% +$750K ﹤0.01% 2619
2019
Q4
$257K Buy
+5,913
New +$124K ﹤0.01% 3106
2019
Q2
Sell
-1,781
Closed -$37K 3563
2019
Q1
$37K Sell
1,781
-31,981
-95% -$635K ﹤0.01% 3372
2018
Q4
$542K Buy
33,762
+31,422
+1,343% +$1.47M ﹤0.01% 2835
2018
Q3
$216K Buy
+2,340
New +$278K ﹤0.01% 3128
2017
Q3
Sell
-5,347
Closed -$731K 3216
2017
Q2
$731K Buy
5,347
+274
+5% +$32.9K ﹤0.01% 2664
2017
Q1
$604K Buy
+5,073
New +$599K ﹤0.01% 2716

Other funds holding CLSD

Renaissance Technologies's CLSD Position: Q4 2025 in Review

Renaissance Technologies sold out of Clearside Biomedical (CLSD) in Q4 2025, closing a stake of 25,247 shares — an estimated $100K sold.

Renaissance Technologies first reported a position in CLSD in Q1 2017 and held it in 29 quarters. The position peaked at $1.98M in Q1 2022. 1 fund tracked by Wall St. Rank holds CLSD as of Q4 2025.

  • Renaissance Technologies reported no remaining Clearside Biomedical position as of Q4 2025 after selling out during the quarter.
  • Renaissance Technologies sold 25,247 Clearside Biomedical shares in Q4 2025, an estimated $100K.
  • Renaissance Technologies first reported a position in Clearside Biomedical in Q1 2017 and held it in 29 quarters.
  • Renaissance Technologies's Clearside Biomedical position peaked at $1.98M in Q1 2022.
  • 1 fund tracked by Wall St. Rank held Clearside Biomedical as of Q4 2025.

Based on Renaissance Technologies's 13F filing for Q4 2025, filed 12 Feb 2026.