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PHS

PFM Health Sciences Portfolio holdings

AUM $1.17B
1-Year Est. Return 92.19%
This Fund
S&P 500
This Quarter Est. Return
-4.77%
1 Year Est. Return
+92.19%
3 Year Est. Return
+240.57%
5 Year Est. Return
+377.11%
10 Year Est. Return
+3,179.38%
AUM
$1.61B
AUM Growth
-$151M
Cap. Flow
-$339M
Cap. Flow %
-21.02%
Top 10 Hldgs %
46.28%
Holding
103
New
28
Increased
9
Reduced
25
Closed
20

Top Buys

Rank Stock Value
1
DXCM icon
DexCom
DXCM
+$24.3M
2
IJH icon
iShares Core S&P Mid-Cap ETF
IJH
+$22.3M
3
NBIX icon
Neurocrine Biosciences
NBIX
+$20.6M
4
BHVN icon
Biohaven
BHVN
+$20.2M
5
RSP icon
Invesco S&P 500 Equal Weight ETF
RSP
+$19.5M

Top Sells

Rank Stock Value
1
CYTK icon
Cytokinetics
CYTK
+$92.8M
2
MRK icon
Merck
MRK
+$61.6M
3
ACHC icon
Acadia Healthcare
ACHC
+$43.5M
4
ELV icon
Elevance Health
ELV
+$29.3M
5
AMGN icon
Amgen
AMGN
+$29.1M

Sector Composition

Rank Sector Weight
1 Healthcare 75.25%
2 Miscellaneous 24.75%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
LLY icon
1
Eli Lilly
LLY
$1T
$231M 14.29%
298,643
– –
IEF icon
2
PUT
iShares 7-10 Year Treasury Bond ETF
IEF
$41.9B
$92.5M 5.73%
+1,000,000
New +$94.5M
XLV icon
3
CALL
State Street Health Care Select Sector SPDR ETF
XLV
$43.3B
$63.9M 3.96%
+464,700
New +$68M
THC icon
4
Tenet Healthcare
THC
$21.7B
$62M 3.84%
491,334
-98,075
-17% -$14.6M
ABBV icon
5
AbbVie
ABBV
$443B
$59M 3.65%
331,741
-72,120
-18% -$13.3M
MCK icon
6
McKesson
MCK
$104B
$55.6M 3.44%
97,498
– –
VRTX icon
7
Vertex Pharmaceuticals
VRTX
$132B
$51.1M 3.17%
126,989
-21,863
-15% -$10.1M
ISRG icon
8
Intuitive Surgical
ISRG
$125B
$48.6M 3.01%
93,073
-44,254
-32% -$23M
EW icon
9
Edwards Lifesciences
EW
$49.7B
$44M 2.73%
594,172
+203,309
+52% +$14.2M
AXSM icon
10
Axsome Therapeutics
AXSM
$11B
$39.5M 2.45%
467,427
– –
PEN icon
11
Penumbra
PEN
$12.6B
$39.5M 2.45%
166,261
– –
ARGX icon
12
argenx
ARGX
$62.7B
$39.2M 2.43%
63,699
-23,133
-27% -$13.6M
EW icon
13
CALL
Edwards Lifesciences
EW
$49.7B
$38.9M 2.41%
+525,400
New +$36.8M
UHS icon
14
Universal Health Services
UHS
$10.4B
$38.4M 2.38%
213,983
– –
UNH icon
15
UnitedHealth
UNH
$353B
$38.2M 2.37%
75,588
– –
UNH icon
16
CALL
UnitedHealth
UNH
$353B
$29M 1.8%
+57,300
New +$32.6M
DHR icon
17
Danaher
DHR
$144B
$28.8M 1.79%
125,515
– –
NVO
18
CALL
Novo Nordisk
NVO
$197B
$28.8M 1.79%
+334,900
New +$36.2M
ICLR icon
19
Icon
ICLR
$12.3B
$27M 1.67%
128,637
+12,105
+10% +$2.83M
DXCM icon
20
DexCom
DXCM
$31.7B
$25.6M 1.58%
+328,763
New +$24.3M
NBIX icon
21
Neurocrine Biosciences
NBIX
$15.8B
$22.8M 1.41%
+166,803
New +$20.6M
IQV icon
22
IQVIA
IQV
$42.3B
$22M 1.36%
111,854
– –
WAT icon
23
Waters Corp
WAT
$39.8B
$21.9M 1.36%
59,053
+7,990
+16% +$2.92M
IJH icon
24
iShares Core S&P Mid-Cap ETF
IJH
$124B
$21.7M 1.34%
+347,637
New +$22.3M
HUM icon
25
Humana
HUM
$48B
$21.1M 1.31%
83,037
-18,917
-19% -$5.07M
1
2 3 4 5

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PFM Health Sciences's Q4 2024 Portfolio in Review

As of Q4 2024, PFM Health Sciences held 103 positions worth $1.61B, down 8.6% from $1.76B the previous quarter. Its ten largest holdings account for 46% of the portfolio.

PFM Health Sciences withdrew a net $339M in Q4 2024, closing 20 positions and reducing 25 holdings. Its most notable exit was Cytokinetics, an estimated $92.8M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 75% of assets, down from 96% a quarter earlier, followed by Miscellaneous.

Against the trend, PFM Health Sciences opened a new position in DexCom worth $25.6M.

  • PFM Health Sciences's largest Q4 2024 buy was DexCom: 328,763 shares worth $25.6M.
  • PFM Health Sciences added most to Edwards Lifesciences in Q4 2024, an estimated $14.2M increase.
  • PFM Health Sciences's biggest Q4 2024 reduction was Intuitive Surgical, cutting an estimated $23M.
  • PFM Health Sciences fully exited Cytokinetics in Q4 2024, selling an estimated $92.8M.
  • PFM Health Sciences's ten largest holdings make up 46% of its $1.61B portfolio in Q4 2024.
  • PFM Health Sciences opened 28 new positions and closed 20 in Q4 2024.
  • PFM Health Sciences's portfolio value fell 8.6% quarter-over-quarter to $1.61B.

Based on PFM Health Sciences's 13F filing for Q4 2024, filed 14 Feb 2025.