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PHS

PFM Health Sciences Portfolio holdings

AUM $1.1B
1-Year Est. Return 57.92%
This Fund
S&P 500
This Quarter Est. Return
+12.54%
1 Year Est. Return
+57.92%
3 Year Est. Return
+183.93%
5 Year Est. Return
+283%
10 Year Est. Return
+2,507.28%
AUM
$2.79B
AUM Growth
+$28.8M
Cap. Flow
-$185M
Cap. Flow %
-6.63%
Top 10 Hldgs %
33.01%
Holding
105
New
22
Increased
19
Reduced
24
Closed
16

Top Buys

Rank Stock Value
1
ISRG icon
Intuitive Surgical
ISRG
+$27.9M
2
A icon
Agilent Technologies
A
+$26.2M
3
ELV icon
Elevance Health
ELV
+$21M
4
CRL icon
Charles River Laboratories
CRL
+$15.9M
5
DXCM icon
DexCom
DXCM
+$14.9M

Top Sells

Rank Stock Value
1
JAZZ icon
Jazz Pharmaceuticals
JAZZ
+$83.8M
2
BMRN icon
BioMarin Pharmaceuticals
BMRN
+$75.6M
3
AXSM icon
Axsome Therapeutics
AXSM
+$33.9M
4
VEEV icon
Veeva Systems
VEEV
+$33.4M
5
NVRO
NEVRO CORP.
NVRO
+$26.3M

Sector Composition

Rank Sector Weight
1 Healthcare 81.16%
2 Financials 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
HZNP
1
DELISTED
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
$124M 4.45%
1,091,840
– –
CYTK icon
2
Cytokinetics
CYTK
$11.2B
$110M 3.94%
2,399,545
-65,471
-3% -$2.82M
LLY icon
3
Eli Lilly
LLY
$1.04T
$109M 3.91%
298,643
– –
MRK icon
4
CALL
Merck
MRK
$315B
$96.7M 3.46%
+871,500
New +$89.1M
CNC icon
5
Centene
CNC
$32.5B
$91.2M 3.27%
1,112,480
– –
HUM icon
6
Humana
HUM
$47.7B
$85.1M 3.05%
166,066
– –
AXSM icon
7
Axsome Therapeutics
AXSM
$12.3B
$84.3M 3.02%
1,092,831
-566,902
-34% -$33.9M
PEN icon
8
Penumbra
PEN
$12.4B
$80.1M 2.87%
360,030
– –
JNJ icon
9
PUT
Johnson & Johnson
JNJ
$615B
$79.5M 2.85%
+450,000
New +$77.7M
UNH icon
10
UnitedHealth
UNH
$392B
$61.5M 2.2%
116,067
+4,513
+4% +$2.39M
RCUS icon
11
Arcus Biosciences
RCUS
$3.77B
$55.9M 2%
2,703,287
-679,946
-20% -$18.7M
ABBV icon
12
AbbVie
ABBV
$448B
$53.2M 1.91%
329,344
+12,181
+4% +$1.87M
LH icon
13
CALL
Labcorp
LH
$23.1B
$53M 1.9%
+261,900
New +$51.2M
PEN icon
14
CALL
Penumbra
PEN
$12.4B
$52.8M 1.89%
237,500
+30,000
+14% +$5.87M
PRTA icon
15
Prothena Corp
PRTA
$442M
$52.7M 1.89%
875,464
+35,226
+4% +$2.06M
QURE icon
16
uniQure
QURE
$2.78B
$52.2M 1.87%
2,302,314
-90,997
-4% -$1.96M
CAH icon
17
Cardinal Health
CAH
$51.7B
$49.2M 1.76%
639,783
– –
MOH icon
18
Molina Healthcare
MOH
$11.6B
$47.5M 1.7%
143,779
– –
IQV icon
19
IQVIA
IQV
$33.1B
$46.9M 1.68%
229,081
– –
CI icon
20
Cigna
CI
$75.4B
$46.8M 1.68%
141,300
– –
DHR icon
21
Danaher
DHR
$126B
$46.6M 1.67%
198,178
– –
IRTC icon
22
iRhythm Holdings
IRTC
$3.49B
$46.2M 1.66%
493,721
– –
SNDX icon
23
Syndax Pharmaceuticals
SNDX
$1.95B
$46.2M 1.65%
1,814,634
+525,561
+41% +$12.3M
BIIB icon
24
Biogen
BIIB
$29.2B
$43.1M 1.54%
155,659
+16,333
+12% +$4.61M
MRK icon
25
Merck
MRK
$315B
$40.8M 1.46%
367,634
+7,114
+2% +$727K
1
2 3 4 5

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CPRC
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KCM
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PFM Health Sciences's Q4 2022 Portfolio in Review

As of Q4 2022, PFM Health Sciences held 105 positions worth $2.79B, up 1% from $2.76B the previous quarter. Its ten largest holdings account for 33% of the portfolio.

PFM Health Sciences withdrew a net $185M in Q4 2022, closing 16 positions and reducing 24 holdings. Its most notable exit was Jazz Pharmaceuticals, an estimated $83.8M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 81% of assets, down from 89% a quarter earlier, followed by Financials.

Against the trend, PFM Health Sciences opened a new position in Intuitive Surgical worth $30.4M.

  • PFM Health Sciences's largest Q4 2022 buy was Intuitive Surgical: 114,450 shares worth $30.4M.
  • PFM Health Sciences added most to Elevance Health in Q4 2022, an estimated $21M increase.
  • PFM Health Sciences's biggest Q4 2022 reduction was BioMarin Pharmaceuticals, cutting an estimated $75.6M.
  • PFM Health Sciences fully exited Jazz Pharmaceuticals in Q4 2022, selling an estimated $83.8M.
  • PFM Health Sciences's ten largest holdings make up 33% of its $2.79B portfolio in Q4 2022.
  • PFM Health Sciences opened 22 new positions and closed 16 in Q4 2022.
  • PFM Health Sciences's portfolio value rose 1% quarter-over-quarter to $2.79B.

Based on PFM Health Sciences's 13F filing for Q4 2022, filed 14 Feb 2023.