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PHS

PFM Health Sciences Portfolio holdings

AUM $1.1B
1-Year Est. Return 57.92%
This Fund
S&P 500
This Quarter Est. Return
+25.74%
1 Year Est. Return
+57.92%
3 Year Est. Return
+183.93%
5 Year Est. Return
+283%
10 Year Est. Return
+2,507.28%
AUM
$1B
AUM Growth
-$297M
Cap. Flow
-$487M
Cap. Flow %
-48.53%
Top 10 Hldgs %
41.28%
Holding
103
New
31
Increased
13
Reduced
33
Closed
25

Top Buys

Rank Stock Value
1
MDT icon
Medtronic
MDT
+$20.8M
2
TMO icon
Thermo Fisher Scientific
TMO
+$20.1M
3
GKOS icon
Glaukos
GKOS
+$19.3M
4
SYK icon
Stryker
SYK
+$18.5M
5
UNH icon
UnitedHealth
UNH
+$17.1M

Top Sells

Rank Stock Value
1
LLY icon
Eli Lilly
LLY
+$150M
2
MCK icon
McKesson
MCK
+$55.9M
3
AXSM icon
Axsome Therapeutics
AXSM
+$38.9M
4
ISRG icon
Intuitive Surgical
ISRG
+$33M
5
COR icon
Cencora
COR
+$25.2M

Sector Composition

Rank Sector Weight
1 Healthcare 96.96%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
WST icon
101
West Pharmaceutical
WST
$24.5B
– –
-18,365
Closed -$4.82M
XBI icon
102
CALL
State Street SPDR S&P Biotech ETF
XBI
$10.1B
– –
-717,400
Closed -$71.9M
1 2 3 4
5

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KCM
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MIA
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PWA
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PFM Health Sciences's Q4 2025 Portfolio in Review

As of Q4 2025, PFM Health Sciences held 103 positions worth $1B, down 23% from $1.3B the previous quarter. Its ten largest holdings account for 41% of the portfolio.

PFM Health Sciences withdrew a net $487M in Q4 2025, closing 25 positions and reducing 33 holdings. Its most notable exit was McKesson, an estimated $55.9M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 97% of assets, up from 88% a quarter earlier.

Against the trend, PFM Health Sciences opened a new position in Medtronic worth $20.5M.

  • PFM Health Sciences's largest Q4 2025 buy was Medtronic: 213,796 shares worth $20.5M.
  • PFM Health Sciences added most to Thermo Fisher Scientific in Q4 2025, an estimated $20.1M increase.
  • PFM Health Sciences's biggest Q4 2025 reduction was Eli Lilly, cutting an estimated $150M.
  • PFM Health Sciences fully exited McKesson in Q4 2025, selling an estimated $55.9M.
  • PFM Health Sciences's ten largest holdings make up 41% of its $1B portfolio in Q4 2025.
  • PFM Health Sciences opened 31 new positions and closed 25 in Q4 2025.
  • PFM Health Sciences's portfolio value fell 23% quarter-over-quarter to $1B.

Based on PFM Health Sciences's 13F filing for Q4 2025, filed 17 Feb 2026.