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PHS

PFM Health Sciences Portfolio holdings

AUM $1.1B
1-Year Est. Return 57.92%
This Fund
S&P 500
This Quarter Est. Return
+9.18%
1 Year Est. Return
+57.92%
3 Year Est. Return
+183.93%
5 Year Est. Return
+283%
10 Year Est. Return
+2,507.28%
AUM
$1.17B
AUM Growth
-$203M
Cap. Flow
-$271M
Cap. Flow %
-23.1%
Top 10 Hldgs %
53.52%
Holding
83
New
18
Increased
13
Reduced
24
Closed
26

Top Buys

Rank Stock Value
1
TEVA icon
Teva Pharmaceuticals
TEVA
+$20M
2
NTRA icon
Natera
NTRA
+$15.8M
3
COR icon
Cencora
COR
+$15.4M
4
MASI
Masimo
MASI
+$15.1M
5
ARQT icon
Arcutis Biotherapeutics
ARQT
+$12.9M

Top Sells

Rank Stock Value
1
VRTX icon
Vertex Pharmaceuticals
VRTX
+$61.6M
2
ABBV icon
AbbVie
ABBV
+$54.1M
3
ELV icon
Elevance Health
ELV
+$38.4M
4
ARGX icon
argenx
ARGX
+$35.8M
5
UHS icon
Universal Health Services
UHS
+$29.2M

Sector Composition

Rank Sector Weight
1 Healthcare 94.92%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
VRTX icon
76
Vertex Pharmaceuticals
VRTX
$119B
– –
-126,989
Closed -$61.6M
XENE icon
77
Xenon Pharmaceuticals
XENE
$6B
– –
-92,236
Closed -$3.09M
XLV icon
78
CALL
State Street Health Care Select Sector SPDR ETF
XLV
$41.7B
– –
-429,700
Closed -$62.7M
XRT icon
79
CALL
State Street SPDR S&P Retail ETF
XRT
$329M
– –
-157,200
Closed -$10.9M
XRT icon
80
State Street SPDR S&P Retail ETF
XRT
$329M
– –
-36,471
Closed -$2.52M
MGX icon
81
Metagenomi Therapeutics
MGX
$46.3M
– –
-885,803
Closed -$1.2M
BOLD
82
Boundless Bio
BOLD
$55.7M
– –
-240,513
Closed -$363K
1 2 3
4

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PFM Health Sciences's Q2 2025 Portfolio in Review

As of Q2 2025, PFM Health Sciences held 83 positions worth $1.17B, down 15% from $1.38B the previous quarter. Its ten largest holdings account for 54% of the portfolio.

PFM Health Sciences withdrew a net $271M in Q2 2025, closing 26 positions and reducing 24 holdings. Its most notable exit was Vertex Pharmaceuticals, an estimated $61.6M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 95% of assets, up from 92% a quarter earlier.

Against the trend, PFM Health Sciences opened a new position in Teva Pharmaceuticals worth $20.8M.

  • PFM Health Sciences's largest Q2 2025 buy was Teva Pharmaceuticals: 1,238,846 shares worth $20.8M.
  • PFM Health Sciences added most to Humana in Q2 2025, an estimated $11.5M increase.
  • PFM Health Sciences's biggest Q2 2025 reduction was AbbVie, cutting an estimated $54.1M.
  • PFM Health Sciences fully exited Vertex Pharmaceuticals in Q2 2025, selling an estimated $61.6M.
  • PFM Health Sciences's ten largest holdings make up 54% of its $1.17B portfolio in Q2 2025.
  • PFM Health Sciences opened 18 new positions and closed 26 in Q2 2025.
  • PFM Health Sciences's portfolio value fell 15% quarter-over-quarter to $1.17B.

Based on PFM Health Sciences's 13F filing for Q2 2025, filed 14 Aug 2025.