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PFM Health Sciences Portfolio holdings

AUM $1.1B
1-Year Est. Return 57.92%
This Fund
S&P 500
This Quarter Est. Return
+8.78%
1 Year Est. Return
+57.92%
3 Year Est. Return
+183.93%
5 Year Est. Return
+283%
10 Year Est. Return
+2,507.28%
AUM
$1.38B
AUM Growth
-$236M
Cap. Flow
-$330M
Cap. Flow %
-23.99%
Top 10 Hldgs %
54.43%
Holding
96
New
13
Increased
16
Reduced
18
Closed
30

Top Buys

Rank Stock Value
1
ELV icon
Elevance Health
ELV
+$35.4M
2
ALNY icon
Alnylam Pharmaceuticals
ALNY
+$22.4M
3
BDX icon
Becton Dickinson
BDX
+$21.2M
4
BBIO icon
BridgeBio Pharma
BBIO
+$20.8M
5
OM icon
Outset Medical
OM
+$20.1M

Top Sells

Rank Stock Value
1
DXCM icon
DexCom
DXCM
+$25.6M
2
NBIX icon
Neurocrine Biosciences
NBIX
+$22.8M
3
IJH icon
iShares Core S&P Mid-Cap ETF
IJH
+$21.7M
4
LLY icon
Eli Lilly
LLY
+$20.7M
5
UNH icon
UnitedHealth
UNH
+$20.3M

Sector Composition

Rank Sector Weight
1 Healthcare 91.81%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
INSM icon
76
Insmed
INSM
$28.2B
– –
-43,774
Closed -$3.02M
IWM icon
77
CALL
iShares Russell 2000 ETF
IWM
$82.8B
– –
-54,800
Closed -$12.1M
JAZZ icon
78
Jazz Pharmaceuticals
JAZZ
$16.7B
– –
-17,597
Closed -$2.17M
KWEB icon
79
CALL
KraneShares CSI China Internet ETF
KWEB
$5.66B
– –
-434,700
Closed -$12.7M
KWEB icon
80
KraneShares CSI China Internet ETF
KWEB
$5.66B
– –
-180,974
Closed -$5.29M
NBIX icon
81
Neurocrine Biosciences
NBIX
$16.6B
– –
-166,803
Closed -$22.8M
NVO
82
CALL
Novo Nordisk
NVO
$207B
– –
-334,900
Closed -$28.8M
RSP icon
83
Invesco S&P 500 Equal Weight ETF
RSP
$99.4B
– –
-108,041
Closed -$18.9M
SPY icon
84
State Street SPDR S&P 500 ETF Trust
SPY
$823B
– –
-12,427
Closed -$7.28M
SWTX
85
CALL
DELISTED
SpringWorks Therapeutics
SWTX
– –
-150,000
Closed -$5.42M
SYK icon
86
Stryker
SYK
$130B
– –
-32,349
Closed -$11.6M
TEVA icon
87
Teva Pharmaceuticals
TEVA
$41B
– –
-397,024
Closed -$8.75M
TGTX icon
88
TG Therapeutics
TGTX
$7.63B
– –
-98,674
Closed -$2.97M
UNH icon
89
CALL
UnitedHealth
UNH
$371B
– –
-57,300
Closed -$29M
UTHR icon
90
United Therapeutics
UTHR
$22.6B
– –
-52,500
Closed -$18.5M
VEEV icon
91
Veeva Systems
VEEV
$37.4B
– –
-55,383
Closed -$11.6M
XBI icon
92
PUT
State Street SPDR S&P Biotech ETF
XBI
$10.2B
– –
-179,100
Closed -$16.1M
XLV icon
93
State Street Health Care Select Sector SPDR ETF
XLV
$42.5B
– –
-83,806
Closed -$12.2M
ITCI
94
DELISTED
Intra-Cellular Therapies Inc.
ITCI
– –
-40,610
Closed -$3.39M
1 2 3
4

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DAM
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MAM
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DAM
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KCM
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MIA
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YL
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SL
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PWA
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PFM Health Sciences's Q1 2025 Portfolio in Review

As of Q1 2025, PFM Health Sciences held 96 positions worth $1.38B, down 15% from $1.61B the previous quarter. Its ten largest holdings account for 54% of the portfolio.

PFM Health Sciences withdrew a net $330M in Q1 2025, closing 30 positions and reducing 18 holdings. Its most notable exit was DexCom, an estimated $25.6M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 92% of assets, up from 75% a quarter earlier.

Against the trend, PFM Health Sciences opened a new position in Elevance Health worth $38.4M.

  • PFM Health Sciences's largest Q1 2025 buy was Elevance Health: 88,222 shares worth $38.4M.
  • PFM Health Sciences added most to BridgeBio Pharma in Q1 2025, an estimated $20.8M increase.
  • PFM Health Sciences's biggest Q1 2025 reduction was Eli Lilly, cutting an estimated $20.7M.
  • PFM Health Sciences fully exited DexCom in Q1 2025, selling an estimated $25.6M.
  • PFM Health Sciences's ten largest holdings make up 54% of its $1.38B portfolio in Q1 2025.
  • PFM Health Sciences opened 13 new positions and closed 30 in Q1 2025.
  • PFM Health Sciences's portfolio value fell 15% quarter-over-quarter to $1.38B.

Based on PFM Health Sciences's 13F filing for Q1 2025, filed 15 May 2025.