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PFM Health Sciences Portfolio holdings

AUM $1.1B
1-Year Est. Return 57.92%
This Fund
S&P 500
This Quarter Est. Return
-4.77%
1 Year Est. Return
+57.92%
3 Year Est. Return
+183.93%
5 Year Est. Return
+283%
10 Year Est. Return
+2,507.28%
AUM
$1.61B
AUM Growth
-$151M
Cap. Flow
-$42.4M
Cap. Flow %
-2.62%
Top 10 Hldgs %
46.28%
Holding
103
New
28
Increased
9
Reduced
25
Closed
20

Top Buys

Rank Stock Value
1
DXCM icon
DexCom
DXCM
+$24.3M
2
IJH icon
iShares Core S&P Mid-Cap ETF
IJH
+$22.3M
3
NBIX icon
Neurocrine Biosciences
NBIX
+$20.6M
4
BHVN icon
Biohaven
BHVN
+$20.2M
5
RSP icon
Invesco S&P 500 Equal Weight ETF
RSP
+$19.5M

Top Sells

Rank Stock Value
1
CYTK icon
Cytokinetics
CYTK
+$92.8M
2
MRK icon
Merck
MRK
+$61.6M
3
ACHC icon
Acadia Healthcare
ACHC
+$43.5M
4
ELV icon
Elevance Health
ELV
+$29.3M
5
AMGN icon
Amgen
AMGN
+$29.1M

Sector Composition

Rank Sector Weight
1 Healthcare 75.25%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
GBIO
76
DELISTED
Generation Bio
GBIO
$835K 0.05%
78,791
– –
CAPR icon
77
Capricor Therapeutics
CAPR
$240M
$750K 0.05%
54,357
-98,422
-64% -$1.72M
VERV
78
DELISTED
Verve Therapeutics
VERV
$711K 0.04%
125,999
– –
BOLD
79
Boundless Bio
BOLD
$65.2M
$697K 0.04%
240,513
– –
BLUE
80
DELISTED
bluebird bio
BLUE
$632K 0.04%
+75,758
New +$662K
TSBX
81
DELISTED
Turnstone Biologics
TSBX
$463K 0.03%
932,348
– –
ACHC icon
82
Acadia Healthcare
ACHC
$2.89B
– –
-686,150
Closed -$43.5M
AMGN icon
83
Amgen
AMGN
$218B
– –
-90,297
Closed -$29.1M
ARKG icon
84
ARK Genomic Revolution ETF
ARKG
$1.65B
– –
-86,934
Closed -$2.23M
BDX icon
85
Becton Dickinson
BDX
$49B
– –
-101,680
Closed -$24.5M
BSX icon
86
Boston Scientific
BSX
$72.5B
– –
-108,469
Closed -$9.09M
CGEM icon
87
Cullinan Oncology
CGEM
$1.07B
– –
-182,810
Closed -$3.06M
CLDX icon
88
Celldex Therapeutics
CLDX
$3.23B
– –
-52,120
Closed -$1.77M
CYTK icon
89
Cytokinetics
CYTK
$10.8B
– –
-1,757,192
Closed -$92.8M
DAWN
90
DELISTED
Day One Biopharmaceuticals
DAWN
– –
-342,172
Closed -$4.77M
ELV icon
91
Elevance Health
ELV
$84B
– –
-56,441
Closed -$29.3M
EPIX
92
DELISTED
ESSA Pharma
EPIX
– –
-2,742,936
Closed -$16.6M
IMVT icon
93
Immunovant
IMVT
$8.02B
– –
-122,701
Closed -$3.5M
INSP icon
94
Inspire Medical Systems
INSP
$1.74B
– –
-98,322
Closed -$20.8M
LUNG icon
95
Pulmonx
LUNG
$90.2M
– –
-368,929
Closed -$3.06M
MRK icon
96
Merck
MRK
$318B
– –
-542,811
Closed -$61.6M
OCUL icon
97
Ocular Therapeutix
OCUL
$1.89B
– –
-402,843
Closed -$3.5M
XBI icon
98
CALL
State Street SPDR S&P Biotech ETF
XBI
$10.1B
– –
-218,200
Closed -$21.6M
XBI icon
99
State Street SPDR S&P Biotech ETF
XBI
$10.1B
– –
-121,845
Closed -$11.8M
CON
100
Concentra Group Holdings
CON
$3.92B
– –
-300,000
Closed -$6.71M
1 2 3
4
5

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PFM Health Sciences's Q4 2024 Portfolio in Review

As of Q4 2024, PFM Health Sciences held 103 positions worth $1.61B, down 8.6% from $1.76B the previous quarter. Its ten largest holdings account for 46% of the portfolio.

PFM Health Sciences's Q4 2024 filing shows 28 new, 9 increased, 25 reduced and 20 closed positions. Its largest new stake was DexCom: 328,763 shares worth $25.6M. The largest sale was Cytokinetics, an estimated $92.8M.

By sector, the portfolio is most concentrated in Healthcare at 75% of assets, down from 96% a quarter earlier.

  • PFM Health Sciences's largest Q4 2024 buy was DexCom: 328,763 shares worth $25.6M.
  • PFM Health Sciences added most to Edwards Lifesciences in Q4 2024, an estimated $14.2M increase.
  • PFM Health Sciences's biggest Q4 2024 reduction was Intuitive Surgical, cutting an estimated $23M.
  • PFM Health Sciences fully exited Cytokinetics in Q4 2024, selling an estimated $92.8M.
  • PFM Health Sciences's ten largest holdings make up 46% of its $1.61B portfolio in Q4 2024.
  • PFM Health Sciences opened 28 new positions and closed 20 in Q4 2024.
  • PFM Health Sciences's portfolio value fell 8.6% quarter-over-quarter to $1.61B.

Based on PFM Health Sciences's 13F filing for Q4 2024, filed 14 Feb 2025.