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PHS

PFM Health Sciences Portfolio holdings

AUM $1.1B
1-Year Est. Return 57.92%
This Fund
S&P 500
This Quarter Est. Return
+12.54%
1 Year Est. Return
+57.92%
3 Year Est. Return
+183.93%
5 Year Est. Return
+283%
10 Year Est. Return
+2,507.28%
AUM
$2.79B
AUM Growth
+$28.8M
Cap. Flow
-$185M
Cap. Flow %
-6.63%
Top 10 Hldgs %
33.01%
Holding
105
New
22
Increased
19
Reduced
24
Closed
16

Top Buys

Rank Stock Value
1
ISRG icon
Intuitive Surgical
ISRG
+$27.9M
2
A icon
Agilent Technologies
A
+$26.2M
3
ELV icon
Elevance Health
ELV
+$21M
4
CRL icon
Charles River Laboratories
CRL
+$15.9M
5
DXCM icon
DexCom
DXCM
+$14.9M

Top Sells

Rank Stock Value
1
JAZZ icon
Jazz Pharmaceuticals
JAZZ
+$83.8M
2
BMRN icon
BioMarin Pharmaceuticals
BMRN
+$75.6M
3
AXSM icon
Axsome Therapeutics
AXSM
+$33.9M
4
VEEV icon
Veeva Systems
VEEV
+$33.4M
5
NVRO
NEVRO CORP.
NVRO
+$26.3M

Sector Composition

Rank Sector Weight
1 Healthcare 81.16%
2 Financials 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
BLUE
76
DELISTED
bluebird bio
BLUE
$1.69M 0.06%
+12,243
New +$1.72M
ITOS
77
DELISTED
iTeos Therapeutics
ITOS
$1.39M 0.05%
70,922
-467,032
-87% -$9.13M
IOBT
78
DELISTED
IO Biotech
IOBT
$1.17M 0.04%
507,640
-1,651,515
-76% -$4.37M
KROS icon
79
Keros Therapeutics
KROS
$199M
$768K 0.03%
+15,999
New +$747K
XENE icon
80
Xenon Pharmaceuticals
XENE
$6.2B
$690K 0.02%
+17,488
New +$637K
BLU
81
DELISTED
BELLUS Health Inc.
BLU
$525K 0.02%
+63,864
New +$595K
JNCE
82
DELISTED
Jounce Therapeutics, Inc. Common Stock
JNCE
$384K 0.01%
345,926
-3,748,562
-92% -$5.34M
SANA icon
83
Sana Biotechnology
SANA
$943M
$248K 0.01%
62,776
-628,688
-91% -$3.07M
VECT
84
DELISTED
VectivBio Holding AG Ordinary Shares
VECT
$221K 0.01%
+25,541
New +$206K
BHVN icon
85
Biohaven
BHVN
$2.15B
$153K 0.01%
+10,988
New +$155K
IOVA icon
86
Iovance Biotherapeutics
IOVA
$2.63B
$85.2K ﹤0.01%
+13,337
New +$104K
BIIB icon
87
CALL
Biogen
BIIB
$30.2B
– –
-166,800
Closed -$44.5M
ICUI icon
88
ICU Medical
ICUI
$4.16B
– –
-160,250
Closed -$24.1M
JAZZ icon
89
Jazz Pharmaceuticals
JAZZ
$16.8B
– –
-571,936
Closed -$83.8M
MYGN icon
90
Myriad Genetics
MYGN
$293M
– –
-742,138
Closed -$14.2M
NTLA icon
91
Intellia Therapeutics
NTLA
$1.54B
– –
-344,868
Closed -$19.3M
OM icon
92
Outset Medical
OM
$95.8M
– –
-48,628
Closed -$11.6M
SGHT icon
93
Sight Sciences
SGHT
$389M
– –
-227,692
Closed -$1.45M
SOPH icon
94
SOPHiA GENETICS
SOPH
$530M
– –
-879,913
Closed -$2.31M
VEEV icon
95
Veeva Systems
VEEV
$34.6B
– –
-202,387
Closed -$33.4M
XLK icon
96
PUT
State Street Technology Select Sector SPDR ETF
XLK
$122B
– –
-767,000
Closed -$45.6M
ZLAB icon
97
Zai Lab
ZLAB
$2.42B
– –
-23,612
Closed -$808K
NVRO
98
DELISTED
NEVRO CORP.
NVRO
– –
-563,560
Closed -$26.3M
CANO
99
DELISTED
Cano Health, Inc.
CANO
– –
-7,769
Closed -$6.74M
PRDS
100
DELISTED
Pardes Biosciences, Inc. Common Stock
PRDS
– –
-285,170
Closed -$528K
1 2 3
4
5

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PFM Health Sciences's Q4 2022 Portfolio in Review

As of Q4 2022, PFM Health Sciences held 105 positions worth $2.79B, up 1% from $2.76B the previous quarter. Its ten largest holdings account for 33% of the portfolio.

PFM Health Sciences withdrew a net $185M in Q4 2022, closing 16 positions and reducing 24 holdings. Its most notable exit was Jazz Pharmaceuticals, an estimated $83.8M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 81% of assets, down from 89% a quarter earlier, followed by Financials.

Against the trend, PFM Health Sciences opened a new position in Intuitive Surgical worth $30.4M.

  • PFM Health Sciences's largest Q4 2022 buy was Intuitive Surgical: 114,450 shares worth $30.4M.
  • PFM Health Sciences added most to Elevance Health in Q4 2022, an estimated $21M increase.
  • PFM Health Sciences's biggest Q4 2022 reduction was BioMarin Pharmaceuticals, cutting an estimated $75.6M.
  • PFM Health Sciences fully exited Jazz Pharmaceuticals in Q4 2022, selling an estimated $83.8M.
  • PFM Health Sciences's ten largest holdings make up 33% of its $2.79B portfolio in Q4 2022.
  • PFM Health Sciences opened 22 new positions and closed 16 in Q4 2022.
  • PFM Health Sciences's portfolio value rose 1% quarter-over-quarter to $2.79B.

Based on PFM Health Sciences's 13F filing for Q4 2022, filed 14 Feb 2023.