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PHS

PFM Health Sciences Portfolio holdings

AUM $1.1B
1-Year Est. Return 57.92%
This Fund
S&P 500
This Quarter Est. Return
-6.97%
1 Year Est. Return
+57.92%
3 Year Est. Return
+183.93%
5 Year Est. Return
+283%
10 Year Est. Return
+2,507.28%
AUM
$2.62B
AUM Growth
-$52.9M
Cap. Flow
+$108M
Cap. Flow %
4.11%
Top 10 Hldgs %
34.14%
Holding
89
New
20
Increased
21
Reduced
12
Closed
10

Sector Composition

Rank Sector Weight
1 Healthcare 93.59%
2 Financials 0.35%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
VERV
51
DELISTED
Verve Therapeutics
VERV
$12.9M 0.49%
845,186
+475,421
+129% +$7.36M
KRTX
52
CALL
DELISTED
Karuna Therapeutics, Inc. Common Stock
KRTX
$12.7M 0.48%
+100,000
New +$11.5M
JNCE
53
DELISTED
Jounce Therapeutics, Inc. Common Stock
JNCE
$12M 0.46%
3,949,668
-23,200
-0.6% -$113K
PRCT icon
54
Procept Biorobotics
PRCT
$1.06B
$11.7M 0.45%
+357,492
New +$13M
SNDX icon
55
Syndax Pharmaceuticals
SNDX
$1.69B
$11.2M 0.43%
580,768
-1,462,609
-72% -$24.4M
ITOS
56
DELISTED
iTeos Therapeutics
ITOS
$11.1M 0.42%
+537,954
New +$12.8M
OSH
57
DELISTED
Oak Street Health, Inc.
OSH
$10.2M 0.39%
618,761
+95,117
+18% +$1.85M
IOBT
58
DELISTED
IO Biotech
IOBT
$10.1M 0.38%
2,159,155
+797,011
+59% +$4.88M
PRTA icon
59
Prothena Corp
PRTA
$425M
$9.37M 0.36%
+345,114
New +$10.1M
ISEE
60
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
$8.72M 0.33%
906,016
-99,200
-10% -$1.25M
NTLA icon
61
Intellia Therapeutics
NTLA
$1.49B
$8.45M 0.32%
163,280
-124,629
-43% -$6.33M
PRAX icon
62
Praxis Precision Medicines
PRAX
$8.58B
$8.08M 0.31%
219,823
+162,168
+281% +$17.3M
EDIT icon
63
Editas Medicine
EDIT
$396M
$7.45M 0.28%
+629,684
New +$8.44M
HOWL icon
64
Werewolf Therapeutics
HOWL
$17.2M
$7.08M 0.27%
1,730,723
+1,145,396
+196% +$5.23M
SGEN
65
CALL
DELISTED
Seagen Inc. Common Stock
SGEN
$7.08M 0.27%
+40,000
New +$5.76M
SGHT icon
66
Sight Sciences
SGHT
$286M
$6.98M 0.27%
+776,281
New +$6.83M
SOPH icon
67
SOPHiA GENETICS
SOPH
$476M
$6.39M 0.24%
1,766,062
-247,962
-12% -$1.26M
SANA icon
68
Sana Biotechnology
SANA
$871M
$6.13M 0.23%
952,733
+597,461
+168% +$3.81M
BCRX icon
69
CALL
BioCryst Pharmaceuticals
BCRX
$2.28B
$5.82M 0.22%
+550,000
New +$5.67M
ACAD icon
70
Acadia Pharmaceuticals
ACAD
$4.43B
$5.42M 0.21%
+384,995
New +$7.18M
AERI
71
DELISTED
Aerie Pharmaceuticals
AERI
$5.25M 0.2%
699,531
-389,035
-36% -$2.74M
BLSA
72
DELISTED
BCLS Acquisition Corp. Class A Ordinary Shares
BLSA
$4.59M 0.18%
464,103
JYAC
73
DELISTED
Jiya Acquisition Corp. Class A Common Stock
JYAC
$4.58M 0.17%
464,103
CMPS
74
Compass Pathways
CMPS
$1.53B
$4.25M 0.16%
+392,764
New +$3.96M
EPIX
75
DELISTED
ESSA Pharma
EPIX
$3.03M 0.12%
+961,716
New +$5.37M

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PFM Health Sciences's Q2 2022 Portfolio in Review

As of Q2 2022, PFM Health Sciences held 89 positions worth $2.62B, down 2% from $2.67B the previous quarter. Its ten largest holdings account for 34% of the portfolio.

PFM Health Sciences deployed $108M of net new capital in Q2 2022, opening 20 new positions and adding to 21 existing holdings. Its largest new stake was Merck: 971,998 shares worth $88.6M.

By sector, the portfolio is most concentrated in Healthcare at 94% of assets, up from 93% a quarter earlier, followed by Financials.

On the sell side, the largest reduction was Syndax Pharmaceuticals, an estimated $24.4M trimmed.

  • PFM Health Sciences's largest Q2 2022 buy was Merck: 971,998 shares worth $88.6M.
  • PFM Health Sciences added most to uniQure in Q2 2022, an estimated $27.1M increase.
  • PFM Health Sciences's biggest Q2 2022 reduction was Syndax Pharmaceuticals, cutting an estimated $24.4M.
  • PFM Health Sciences fully exited Outset Medical in Q2 2022, selling an estimated $128M.
  • PFM Health Sciences's ten largest holdings make up 34% of its $2.62B portfolio in Q2 2022.
  • PFM Health Sciences opened 20 new positions and closed 10 in Q2 2022.
  • PFM Health Sciences's portfolio value fell 2% quarter-over-quarter to $2.62B.

Based on PFM Health Sciences's 13F filing for Q2 2022, filed 15 Aug 2022.