OM

Opaleye Management Portfolio holdings

AUM $494M
This Quarter Return
+1.9%
1 Year Return
+68.17%
3 Year Return
+608.37%
5 Year Return
+807.76%
10 Year Return
+24,567.29%
AUM
$681M
AUM Growth
+$681M
Cap. Flow
-$30.5M
Cap. Flow %
-4.47%
Top 10 Hldgs %
54.41%
Holding
74
New
15
Increased
15
Reduced
15
Closed
16

Top Buys

1
BBIO icon
BridgeBio Pharma
BBIO
$36M
2
AUTL
Autolus Therapeutics
AUTL
$12.1M
3
IRON icon
Disc Medicine
IRON
$11M
4
KROS icon
Keros Therapeutics
KROS
$9.69M
5
MGNX icon
MacroGenics
MGNX
$9.41M

Top Sells

1
EIDX
Eidos Therapeutics, Inc. Common Stock
EIDX
$41.5M
2
CCXI
ChemoCentryx, Inc.
CCXI
$21.7M
3
TGTX icon
TG Therapeutics
TGTX
$20.2M
4
CRDF icon
Cardiff Oncology
CRDF
$10.1M
5
KALV icon
KalVista Pharmaceuticals
KALV
$8.93M

Sector Composition

1 Healthcare 98.06%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
ALPN
51
DELISTED
Alpine Immune Sciences, Inc. Common Stock
ALPN
$1.66M 0.24% +156,500 New +$1.66M
WHWK
52
Whitehawk Therapeutics, Inc. Common Stock
WHWK
$84.8M
$1.29M 0.19% +1,000,000 New +$1.29M
AYLA
53
DELISTED
Ayala Pharmaceuticals, Inc. Common Stock
AYLA
$1.18M 0.17% +108,551 New +$1.18M
CFRX
54
DELISTED
ContraFect Corporation
CFRX
$1.17M 0.17% 244,000 -196,000 -45% -$941K
DNTH icon
55
Dianthus Therapeutics
DNTH
$759M
$1.05M 0.15% 88,400 +40,596 +85% +$481K
VIRX
56
DELISTED
Viracta Therapeutics, Inc. Common Stock
VIRX
$958K 0.14% +103,600 New +$958K
LPTX icon
57
Leap Therapeutics
LPTX
$12M
$737K 0.11% +388,100 New +$737K
BLRX
58
BioLineRX
BLRX
$16.2M
$47K 0.01% 16,667 – –
AMRN
59
Amarin Corp
AMRN
$311M
– – -225,000 Closed -$1.1M
ATXS icon
60
Astria Therapeutics
ATXS
$349M
– – -187,750 Closed -$402K
FULC icon
61
Fulcrum Therapeutics
FULC
$351M
– – -88,300 Closed -$1.03M
KALV icon
62
KalVista Pharmaceuticals
KALV
$678M
– – -470,203 Closed -$8.93M
MRUS icon
63
Merus
MRUS
$4.98B
– – -353,000 Closed -$6.19M
PRAX icon
64
Praxis Precision Medicines
PRAX
$958M
– – -63,416 Closed -$3.49M
RYTM icon
65
Rhythm Pharmaceuticals
RYTM
$6.85B
– – -115,000 Closed -$3.42M
TGTX icon
66
TG Therapeutics
TGTX
$4.65B
– – -387,500 Closed -$20.2M
INFI
67
DELISTED
Infinity Pharmaceuticals, Inc.
INFI
– – -3,171,800 Closed -$6.72M
CNCE
68
DELISTED
Concert Pharmaceuticals, Inc.
CNCE
– – -254,000 Closed -$3.21M
TCDA
69
DELISTED
Tricida, Inc. Common Stock
TCDA
– – -959,000 Closed -$6.76M
AKUS
70
DELISTED
Akouos, Inc. Common Stock
AKUS
– – -45,459 Closed -$901K
CCXI
71
DELISTED
ChemoCentryx, Inc.
CCXI
– – -350,000 Closed -$21.7M
FPRX
72
DELISTED
Five Prime Therapeutics, Inc.
FPRX
– – -381,900 Closed -$6.5M
FSDC
73
DELISTED
FS Development Corp. Class A Common Stock
FSDC
– – -704,400 Closed -$7.75M
EIDX
74
DELISTED
Eidos Therapeutics, Inc. Common Stock
EIDX
– – -315,550 Closed -$41.5M
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