OM

Opaleye Management Portfolio holdings

AUM $494M
This Quarter Return
+51.73%
1 Year Return
+68.17%
3 Year Return
+608.37%
5 Year Return
+807.76%
10 Year Return
+24,567.28%
AUM
$361M
AUM Growth
+$361M
Cap. Flow
+$26.3M
Cap. Flow %
7.29%
Top 10 Hldgs %
42.47%
Holding
67
New
20
Increased
17
Reduced
12
Closed
14

Top Buys

1
QURE icon
uniQure
QURE
$12.2M
2
ASND icon
Ascendis Pharma
ASND
$11.2M
3
NVTA
Invitae Corporation
NVTA
$10.3M
4
CPRX icon
Catalyst Pharmaceutical
CPRX
$9.31M
5
MRTX
Mirati Therapeutics, Inc. Common Stock
MRTX
$7.7M

Top Sells

1
LOXO
Loxo Oncology, Inc
LOXO
$24.5M
2
BPMC
Blueprint Medicines
BPMC
$13.6M
3
AMRN
Amarin Corp
AMRN
$12.6M
4
XNCR icon
Xencor
XNCR
$6.51M
5
SGMO icon
Sangamo Therapeutics
SGMO
$5.74M

Sector Composition

1 Healthcare 93.64%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
LJPC
51
DELISTED
La Jolla Pharmaceutical Company
LJPC
$386K 0.11%
+60,000
New +$386K
BLRX
52
BioLineRX
BLRX
$15.5M
$108K 0.03%
250,000
– –
CTIC
53
DELISTED
CTI BioPharma Corp. (DE) Common Stock
CTIC
– –
-1,400,000
Closed -$1.03M
LOXO
54
DELISTED
Loxo Oncology, Inc
LOXO
– –
-175,000
Closed -$24.5M
ARQL
55
DELISTED
Arqule Inc
ARQL
– –
-200,000
Closed -$358K
PTE
56
DELISTED
PolarityTE, Inc. Common Stock
PTE
– –
-400,000
Closed -$5.4M
SIOX
57
DELISTED
Sio Gene Therapies Inc. Common Stock
SIOX
– –
-580,000
Closed -$577K
IMGN
58
DELISTED
Immunogen Inc
IMGN
– –
-1,021,000
Closed -$4.9M
XNCR icon
59
Xencor
XNCR
$594M
– –
-180,000
Closed -$6.51M
VRDN icon
60
Viridian Therapeutics
VRDN
$1.59B
– –
-385,000
Closed -$1.17M
SGMO icon
61
Sangamo Therapeutics
SGMO
$161M
– –
-500,000
Closed -$5.74M
PLX icon
62
Protalix BioTherapeutics
PLX
$128M
– –
-2,500,000
Closed -$777K
PBYI icon
63
Puma Biotechnology
PBYI
$258M
– –
-100,000
Closed -$2.04M
MGNX icon
64
MacroGenics
MGNX
$121M
– –
-150,000
Closed -$1.91M
COLL icon
65
Collegium Pharmaceutical
COLL
$1.25B
– –
-80,000
Closed -$1.37M
ASRT icon
66
Assertio
ASRT
$78M
– –
-120,000
Closed -$433K
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