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Opaleye Management Portfolio holdings
AUM
$1.1B
Turnover
32.84%
1-Year Est. Return
197.64%
This Fund
S&P 500
This Quarter
Est. Return
-24.99%
1 Year Est. Return
+197.64%
3 Year Est. Return
+748.31%
5 Year Est. Return
+1,163.14%
10 Year Est. Return
+87,953.69%
AUM
$160M
AUM Growth
-$78.8M
(-33%)
Cap. Flow
-$21.6M
Cap. Flow
% of AUM
-13.46%
Top 10 Holdings %
Top 10 Hldgs %
42.9%
Holding
67
New
14
Increased
18
Reduced
12
Closed
14
Avg Time Held
0.7
years
Top 10 Avg Time Held
0.5
years
Top 20 Avg Time Held
0.7
years
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
Agios Pharmaceuticals
AGIO
|
+$4.49M |
| 2 |
Chimerix, Inc.
CMRX
|
+$4.41M |
| 3 |
Tvardi Therapeutics
TVRD
|
+$3.55M |
| 4 |
IMMU
Immunomedics Inc
IMMU
|
+$2.33M |
| 5 |
Sage Therapeutics
SAGE
|
+$2.29M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
RLYP
RELYPSA INC COM
RLYP
|
+$6.24M |
| 2 |
CEMP
Cempra, Inc.
CEMP
|
+$6.23M |
| 3 |
Tonix Pharmaceuticals
TNXP
|
+$4.33M |
| 4 |
Avinger, Inc. Common Stock
AVGR
|
+$4.32M |
| 5 |
Supernus Pharmaceuticals
SUPN
|
+$3.85M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Healthcare | 88.12% |
| 2 | Miscellaneous | 11.88% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | Held Since | |
|---|---|---|---|---|---|---|---|
51
Cellectis
CLLS
$111M
| – | – |
-50,000
| Closed | -$1.55M | – |
|
52
MacroGenics
MGNX
$215M
| – | – |
-35,000
| Closed | -$1.08M | – |
|
53
Neurocrine Biosciences
NBIX
$13.9B
| – | – |
-55,000
| Closed | -$3.11M | – |
|
54
DELISTED
SANGAMO THERAPEUTICS INC
SGMO
| – | – |
-60,000
| Closed | -$548K | – |
|
|
55
Tonix Pharmaceuticals
TNXP
$110M
| – | – |
0
| – | -$4.33M |
2015 Q2
3 quarters
|
|
|
56
DELISTED
Avinger, Inc. Common Stock
AVGR
| – | – |
-2
| Closed | -$4.32M | – |
|
|
AGRX
57
DELISTED
Agile Therapeutics
AGRX
| – | – |
-150
| Closed | -$2.93M | – |
|
|
ALDR
58
DELISTED
Alder Biopharmaceuticals
ALDR
| – | – |
-65,000
| Closed | -$2.15M | – |
|
|
CEMP
59
DELISTED
Cempra, Inc.
CEMP
| – | – |
-200,000
| Closed | -$6.23M | – |
|
|
VTAE
60
DELISTED
VITAE PHARMACEUTICALS INC COMMON STOCK
VTAE
| – | – |
-58,500
| Closed | -$1.06M | – |
|
|
RLYP
61
DELISTED
RELYPSA INC COM
RLYP
| – | – |
-220,000
| Closed | -$6.24M | – |
|
|
LJPC
62
DELISTED
La Jolla Pharmaceutical Company
LJPC
| – | – |
-140,000
| Closed | -$3.78M | – |
|
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Opaleye Management's Q1 2016 Portfolio in Review
As of Q1 2016, Opaleye Management held 67 positions worth $160M, down 33% from $239M the previous quarter. Its ten largest holdings account for 43% of the portfolio.
Opaleye Management withdrew a net $21.6M in Q1 2016, closing 14 positions and reducing 12 holdings. Its most notable exit was RELYPSA INC COM, an estimated $6.24M position sold in full.
By sector, the portfolio is most concentrated in Healthcare at 88% of assets, up from 88% a quarter earlier, followed by Miscellaneous.
Against the trend, Opaleye Management opened a new position in Agios Pharmaceuticals worth $4.26M.
- Opaleye Management's largest Q1 2016 buy was Agios Pharmaceuticals: 105,000 shares worth $4.26M.
- Opaleye Management added most to Tvardi Therapeutics in Q1 2016, an estimated $3.55M increase.
- Opaleye Management's biggest Q1 2016 reduction was Supernus Pharmaceuticals, cutting an estimated $3.85M.
- Opaleye Management fully exited RELYPSA INC COM in Q1 2016, selling an estimated $6.24M.
- Opaleye Management's ten largest holdings make up 43% of its $160M portfolio in Q1 2016.
- Opaleye Management opened 14 new positions and closed 14 in Q1 2016.
- Opaleye Management's portfolio value fell 33% quarter-over-quarter to $160M.
Based on Opaleye Management's 13F filing for Q1 2016, filed 16 May 2016.