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Opaleye Management Portfolio holdings

AUM $1.1B
1-Year Est. Return 197.64%
This Fund
S&P 500
This Quarter Est. Return
+20.47%
1 Year Est. Return
+197.64%
3 Year Est. Return
+748.31%
5 Year Est. Return
+1,163.14%
10 Year Est. Return
+87,953.74%
AUM
$239M
AUM Growth
+$36M
Cap. Flow
+$7.18M
Cap. Flow %
3%
Top 10 Hldgs %
37.89%
Holding
60
New
11
Increased
16
Reduced
15
Closed
7

Top Buys

Rank Stock Value
1
ASRT
Assertio
ASRT
+$5.63M
2
RLYP
RELYPSA INC COM
RLYP
+$4.74M
3
SAGE
Sage Therapeutics
SAGE
+$3.96M
4
LJPC
La Jolla Pharmaceutical Company
LJPC
+$3.82M
5
BPMC
Blueprint Medicines
BPMC
+$3.26M

Top Sells

Rank Stock Value
1
CMRX
Chimerix, Inc.
CMRX
+$11.8M
2
ZSPH
ZS PHARMA INC COMS TK (DE)
ZSPH
+$6.24M
3
CEMP
Cempra, Inc.
CEMP
+$4.45M
4
NBIX icon
Neurocrine Biosciences
NBIX
+$3.56M
5
MNTA
Momenta Pharmaceuticals, Inc.
MNTA
+$2.63M

Sector Composition

Rank Sector Weight
1 Healthcare 87.84%
2 Miscellaneous 12.16%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ALPN
51
DELISTED
Alpine Immune Sciences Inc
ALPN
– –
-43,800
Closed -$2.27M
MNTA
52
DELISTED
Momenta Pharmaceuticals, Inc.
MNTA
– –
-160,000
Closed -$2.63M
INNL
53
DELISTED
Innocoll Holdings plc Ordinary Shares
INNL
– –
-55,543
Closed -$695K
ZSPH
54
DELISTED
ZS PHARMA INC COMS TK (DE)
ZSPH
– –
-95,000
Closed -$6.24M
CELGZ
55
DELISTED
Celgene Corporation Contingent Value Rights
CELGZ
– –
-340,000
Closed -$547K
1 2
3

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Opaleye Management's Q4 2015 Portfolio in Review

As of Q4 2015, Opaleye Management held 60 positions worth $239M, up 18% from $203M the previous quarter. Its ten largest holdings account for 38% of the portfolio.

Opaleye Management deployed $7.18M of net new capital in Q4 2015, opening 11 new positions and adding to 16 existing holdings. Its largest new stake was Assertio: 5,000 shares worth $5.44M.

By sector, the portfolio is most concentrated in Healthcare at 88% of assets, down from 90% a quarter earlier, followed by Miscellaneous.

On the sell side, the largest reduction was Cempra, Inc., an estimated $4.45M trimmed.

  • Opaleye Management's largest Q4 2015 buy was Assertio: 5,000 shares worth $5.44M.
  • Opaleye Management added most to Sage Therapeutics in Q4 2015, an estimated $3.96M increase.
  • Opaleye Management's biggest Q4 2015 reduction was Cempra, Inc., cutting an estimated $4.45M.
  • Opaleye Management fully exited Chimerix, Inc. in Q4 2015, selling an estimated $11.8M.
  • Opaleye Management's ten largest holdings make up 38% of its $239M portfolio in Q4 2015.
  • Opaleye Management opened 11 new positions and closed 7 in Q4 2015.
  • Opaleye Management's portfolio value rose 18% quarter-over-quarter to $239M.

Based on Opaleye Management's 13F filing for Q4 2015, filed 12 Feb 2016.