OM

Opaleye Management Portfolio holdings

AUM $494M
This Quarter Return
+60.43%
1 Year Return
+68.17%
3 Year Return
+608.37%
5 Year Return
+807.76%
10 Year Return
+24,567.28%
AUM
$242M
AUM Growth
+$242M
Cap. Flow
-$10.2M
Cap. Flow %
-4.21%
Top 10 Hldgs %
67.89%
Holding
53
New
6
Increased
20
Reduced
10
Closed
11

Top Buys

1
RYTM icon
Rhythm Pharmaceuticals
RYTM
$11M
2
TELA icon
TELA Bio
TELA
$3.35M
3
LRMR icon
Larimar Therapeutics
LRMR
$2.33M
4
OCUL icon
Ocular Therapeutix
OCUL
$2.03M
5
EWTX icon
Edgewise Therapeutics
EWTX
$1.81M

Top Sells

1
KNSA icon
Kiniksa Pharmaceuticals
KNSA
$7.89M
2
RETA
Reata Pharmaceuticals, Inc. Class A Common Stock
RETA
$5.58M
3
INBX
Inhibrx, Inc. Common Stock
INBX
$5.34M
4
MASS icon
908 Devices
MASS
$3.43M
5
CLDX icon
Celldex Therapeutics
CLDX
$2.43M

Sector Composition

1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
LENZ
26
LENZ Therapeutics
LENZ
$1.12B
$1.83M 0.76%
577,250
+117,250
+25% +$372K
THRX
27
DELISTED
Theseus Pharmaceuticals, Inc. Common Stock
THRX
$1.28M 0.53%
220,650
+188,350
+583% +$1.09M
IMPL
28
DELISTED
Impel Pharmaceuticals Inc. Common Stock
IMPL
$1.24M 0.51%
255,250
+110,608
+76% +$539K
ATXS icon
29
Astria Therapeutics
ATXS
$394M
$1.21M 0.5%
+133,500
New +$1.21M
MODD icon
30
Modular Medical
MODD
$39.7M
$1.14M 0.47%
275,422
– –
ALLK
31
DELISTED
Allakos
ALLK
$939K 0.39%
+153,500
New +$939K
CMRX
32
DELISTED
Chimerix, Inc.
CMRX
$704K 0.29%
365,000
-1,065,000
-74% -$2.05M
DERM icon
33
Journey Medical
DERM
$169M
$638K 0.26%
259,293
+13,560
+6% +$33.4K
MOR
34
DELISTED
MorphoSys AG American Depositary Shares
MOR
$609K 0.25%
+121,015
New +$609K
EDAP
35
EDAP TMS
EDAP
$103M
$588K 0.24%
+71,300
New +$588K
NPCE icon
36
Neuropace
NPCE
$310M
$436K 0.18%
116,324
+26,224
+29% +$98.3K
LUMO
37
DELISTED
Lumos Pharma, Inc. Common Stock
LUMO
$412K 0.17%
46,576
+25,056
+116% +$222K
NGNE icon
38
Neurogene
NGNE
$284M
$368K 0.15%
575,000
-35,000
-6% -$22.4K
OPTN
39
DELISTED
OptiNose
OPTN
$333K 0.14%
90,970
– –
MGTX icon
40
MeiraGTx Holdings
MGTX
$590M
$84K 0.03%
+10,000
New +$84K
IDYA icon
41
IDEAYA Biosciences
IDYA
$2.26B
$22K 0.01%
+1,500
New +$22K
BLRX
42
BioLineRX
BLRX
$15.5M
$16K 0.01%
16,667
– –
FMTX
43
DELISTED
Forma Therapeutics Holdings, Inc. Common Stock
FMTX
– –
-58,700
Closed -$404K
RETA
44
DELISTED
Reata Pharmaceuticals, Inc. Class A Common Stock
RETA
– –
-183,750
Closed -$5.58M
MRNS
45
DELISTED
Marinus Pharmaceuticals, Inc
MRNS
– –
-68,900
Closed -$333K
VSTM icon
46
Verastem
VSTM
$585M
– –
-1,590,000
Closed -$1.84M
MGNX icon
47
MacroGenics
MGNX
$121M
– –
-208,300
Closed -$614K
MASS icon
48
908 Devices
MASS
$199M
– –
-166,406
Closed -$3.43M
KNSA icon
49
Kiniksa Pharmaceuticals
KNSA
$2.63B
– –
-814,250
Closed -$7.89M
HYPR icon
50
Hyperfine
HYPR
$88M
– –
-763,075
Closed -$1.7M
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