OM

Opaleye Management Portfolio holdings

AUM $494M
This Quarter Return
+51.73%
1 Year Return
+68.17%
3 Year Return
+608.37%
5 Year Return
+807.76%
10 Year Return
+24,567.28%
AUM
$361M
AUM Growth
+$361M
Cap. Flow
+$26.3M
Cap. Flow %
7.29%
Top 10 Hldgs %
42.47%
Holding
67
New
20
Increased
17
Reduced
12
Closed
14

Top Buys

1
QURE icon
uniQure
QURE
$12.2M
2
ASND icon
Ascendis Pharma
ASND
$11.2M
3
NVTA
Invitae Corporation
NVTA
$10.3M
4
CPRX icon
Catalyst Pharmaceutical
CPRX
$9.31M
5
MRTX
Mirati Therapeutics, Inc. Common Stock
MRTX
$7.7M

Top Sells

1
LOXO
Loxo Oncology, Inc
LOXO
$24.5M
2
BPMC
Blueprint Medicines
BPMC
$13.6M
3
AMRN
Amarin Corp
AMRN
$12.6M
4
XNCR icon
Xencor
XNCR
$6.51M
5
SGMO icon
Sangamo Therapeutics
SGMO
$5.74M

Sector Composition

1 Healthcare 93.64%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
SBBP
26
DELISTED
Strongbridge Biopharma plc.
SBBP
$5.74M 1.59%
1,152,500
-237,500
-17% -$1.18M
DERM
27
DELISTED
Dermira, Inc.
DERM
$5.42M 1.5%
400,000
+325,000
+433% +$4.4M
ACAD icon
28
Acadia Pharmaceuticals
ACAD
$4.34B
$5.37M 1.49%
200,000
+5,000
+3% +$134K
XOMA icon
29
Xoma
XOMA
$421M
$4.95M 1.37%
400,000
– –
HZNP
30
DELISTED
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
$4.89M 1.35%
+185,000
New +$4.89M
VKTX icon
31
Viking Therapeutics
VKTX
$3.02B
$4.82M 1.34%
485,000
-340,000
-41% -$3.38M
EIDX
32
DELISTED
Eidos Therapeutics, Inc. Common Stock
EIDX
$4.69M 1.3%
200,000
+60,000
+43% +$1.41M
TVTX icon
33
Travere Therapeutics
TVTX
$1.75B
$4.64M 1.28%
+205,000
New +$4.64M
ABEO icon
34
Abeona Therapeutics
ABEO
$356M
$4.12M 1.14%
560,000
+110,000
+24% +$810K
TVRD
35
Tvardi Therapeutics, Inc. Common Stock
TVRD
$270M
$3.92M 1.09%
+200,000
New +$3.92M
ATXI
36
DELISTED
Avenue Therapeutics, Inc. Common Stock
ATXI
$3.8M 1.05%
800,000
+304,000
+61% +$1.44M
AIMT
37
DELISTED
Aimmune Therapeutics, Inc.
AIMT
$3.69M 1.02%
165,000
+15,000
+10% +$335K
ACOR
38
DELISTED
Acorda Therapeutics, Inc.
ACOR
$3.52M 0.98%
+265,000
New +$3.52M
SWAV
39
DELISTED
Shockwave Medical, Inc. Common Stock
SWAV
$3.08M 0.85%
+92,100
New +$3.08M
FENC icon
40
Fennec Pharmaceuticals
FENC
$247M
$3.06M 0.85%
630,000
-270,000
-30% -$1.31M
CDTX icon
41
Cidara Therapeutics
CDTX
$1.61B
$2.65M 0.73%
1,000,000
-200,000
-17% -$530K
LQDA icon
42
Liquidia Corp
LQDA
$2.52B
$2.56M 0.71%
+225,000
New +$2.56M
APLS icon
43
Apellis Pharmaceuticals
APLS
$3.51B
$2.24M 0.62%
115,000
-160,000
-58% -$3.12M
CMRX
44
DELISTED
Chimerix, Inc.
CMRX
$2.02M 0.56%
960,000
-1,060,000
-52% -$2.23M
CRNX icon
45
Crinetics Pharmaceuticals
CRNX
$3.26B
$1.66M 0.46%
+73,000
New +$1.66M
ESTA icon
46
Establishment Labs
ESTA
$1.11B
$1.2M 0.33%
+50,000
New +$1.2M
ZYME icon
47
Zymeworks
ZYME
$1.07B
$890K 0.25%
55,000
-50,000
-48% -$809K
THOR
48
DELISTED
Synthorx, Inc. Common Stock
THOR
$815K 0.23%
+40,000
New +$815K
FOMX
49
DELISTED
Foamix Pharmaceuticals Ltd. Ordinary Shares
FOMX
$675K 0.19%
+180,000
New +$675K
KURA icon
50
Kura Oncology
KURA
$732M
$418K 0.12%
+25,200
New +$418K
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