OM

Opaleye Management Portfolio holdings

AUM $494M
1-Year Return 68.17%
This Quarter Return
-20.34%
1 Year Return
+68.17%
3 Year Return
+608.37%
5 Year Return
+807.76%
10 Year Return
+24,567.28%
AUM
$268M
AUM Growth
-$125M
Cap. Flow
-$30.8M
Cap. Flow %
-11.49%
Top 10 Hldgs %
57.14%
Holding
61
New
14
Increased
11
Reduced
11
Closed
14

Top Buys

1
AVTX icon
Avalo Therapeutics
AVTX
$6.21M
2
EPZM
Epizyme, Inc
EPZM
$5.7M
3
IMGN
Immunogen Inc
IMGN
$4.9M
4
AIMT
Aimmune Therapeutics, Inc.
AIMT
$3.59M
5
ABEO icon
Abeona Therapeutics
ABEO
$3.21M

Top Sells

1
AGIO icon
Agios Pharmaceuticals
AGIO
$10M
2
AMAG
AMAG Pharmaceuticals, Inc.
AMAG
$8.4M
3
XENE icon
Xenon Pharmaceuticals
XENE
$7.01M
4
RARE icon
Ultragenyx Pharmaceutical
RARE
$6.11M
5
OCUL icon
Ocular Therapeutix
OCUL
$5.5M

Sector Composition

1 Healthcare 98.46%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
ETON icon
26
Eton Pharmaceutcials
ETON
$479M
$3.2M 1.19%
+523,000
New +$3.2M
ACAD icon
27
Acadia Pharmaceuticals
ACAD
$4.3B
$3.15M 1.18%
195,000
– –
TCDA
28
DELISTED
Tricida, Inc. Common Stock
TCDA
$2.9M 1.08%
123,000
+72,000
+141% +$1.7M
DNTH icon
29
Dianthus Therapeutics
DNTH
$794M
$2.88M 1.07%
31,563
-13,750
-30% -$1.25M
CDTX icon
30
Cidara Therapeutics
CDTX
$1.65B
$2.82M 1.05%
60,000
– –
ATXI
31
DELISTED
Avenue Therapeutics, Inc. Common Stock
ATXI
$2.68M 1%
+441
New +$2.68M
TGTX icon
32
TG Therapeutics
TGTX
$5.06B
$2.26M 0.84%
550,000
+200,000
+57% +$820K
PBYI icon
33
Puma Biotechnology
PBYI
$257M
$2.04M 0.76%
+100,000
New +$2.04M
EIDX
34
DELISTED
Eidos Therapeutics, Inc. Common Stock
EIDX
$1.93M 0.72%
+140,000
New +$1.93M
MGNX icon
35
MacroGenics
MGNX
$123M
$1.91M 0.71%
+150,000
New +$1.91M
CMTA
36
DELISTED
Clementia Pharmaceuticals Inc.
CMTA
$1.76M 0.66%
150,000
+1,168
+0.8% +$13.7K
ZYME icon
37
Zymeworks
ZYME
$1.07B
$1.54M 0.58%
+105,000
New +$1.54M
COLL icon
38
Collegium Pharmaceutical
COLL
$1.24B
$1.37M 0.51%
+80,000
New +$1.37M
VRDN icon
39
Viridian Therapeutics
VRDN
$1.52B
$1.17M 0.44%
25,667
-67,380
-72% -$3.06M
CTIC
40
DELISTED
CTI BioPharma Corp. (DE) Common Stock
CTIC
$1.03M 0.38%
1,400,000
-150,000
-10% -$110K
PLX icon
41
Protalix BioTherapeutics
PLX
$127M
$777K 0.29%
250,000
– –
ODT
42
DELISTED
Odonate Therapeutics, Inc. Common Stock
ODT
$690K 0.26%
+49,000
New +$690K
SIOX
43
DELISTED
Sio Gene Therapies Inc. Common Stock
SIOX
$577K 0.22%
+72,500
New +$577K
DERM
44
DELISTED
Dermira, Inc.
DERM
$539K 0.2%
75,000
-22,400
-23% -$161K
ASRT icon
45
Assertio
ASRT
$77.7M
$433K 0.16%
+30,000
New +$433K
ARQL
46
DELISTED
Arqule Inc
ARQL
$358K 0.13%
200,000
-350,000
-64% -$627K
BLRX
47
BioLineRX
BLRX
$15.1M
$109K 0.04%
417
– –
AGIO icon
48
Agios Pharmaceuticals
AGIO
$2.1B
– –
-130,000
Closed -$10M
ARDX icon
49
Ardelyx
ARDX
$1.58B
– –
-650,000
Closed -$2.83M
CLLS
50
Cellectis
CLLS
$264M
– –
-110,000
Closed -$3.1M
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