OM

Opaleye Management Portfolio holdings

AUM $494M
1-Year Return 68.17%
This Quarter Return
+30.1%
1 Year Return
+68.17%
3 Year Return
+608.37%
5 Year Return
+807.76%
10 Year Return
+24,567.28%
AUM
$393M
AUM Growth
+$6.69M
Cap. Flow
+$2.94M
Cap. Flow %
0.75%
Top 10 Hldgs %
57.16%
Holding
48
New
12
Increased
9
Reduced
16
Closed
1

Top Buys

1
XENE icon
Xenon Pharmaceuticals
XENE
$7.01M
2
HROW icon
Harrow
HROW
$4.5M
3
ACAD icon
Acadia Pharmaceuticals
ACAD
$4.05M
4
IOVA icon
Iovance Biotherapeutics
IOVA
$3.66M
5
TVRD
Tvardi Therapeutics, Inc. Common Stock
TVRD
$3.11M

Top Sells

1
FGEN icon
FibroGen
FGEN
$9.72M
2
VKTX icon
Viking Therapeutics
VKTX
$6.53M
3
AXGN icon
Axogen
AXGN
$5.16M
4
BFRA
Biofrontera AG American Depositary Shares
BFRA
$4.24M
5
BPMC
Blueprint Medicines
BPMC
$3.9M

Sector Composition

1 Healthcare 97.59%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
CDTX icon
26
Cidara Therapeutics
CDTX
$1.65B
$5.28M 1.34%
60,000
– –
CORI
27
DELISTED
Corium International, Inc.
CORI
$5.23M 1.33%
550,000
-250,000
-31% -$2.38M
CMRX
28
DELISTED
Chimerix, Inc.
CMRX
$4.61M 1.17%
1,185,000
+35,000
+3% +$136K
HROW icon
29
Harrow
HROW
$1.34B
$4.5M 1.15%
+1,620,000
New +$4.5M
ACAD icon
30
Acadia Pharmaceuticals
ACAD
$4.3B
$4.05M 1.03%
+195,000
New +$4.05M
IOVA icon
31
Iovance Biotherapeutics
IOVA
$796M
$3.66M 0.93%
+325,000
New +$3.66M
CTIC
32
DELISTED
CTI BioPharma Corp. (DE) Common Stock
CTIC
$3.35M 0.85%
1,550,000
+1,388,600
+860% +$3M
TVRD
33
Tvardi Therapeutics, Inc. Common Stock
TVRD
$285M
$3.11M 0.79%
+3,611
New +$3.11M
ARQL
34
DELISTED
Arqule Inc
ARQL
$3.11M 0.79%
550,000
+130,000
+31% +$736K
CLLS
35
Cellectis
CLLS
$264M
$3.1M 0.79%
+110,000
New +$3.1M
ARDX icon
36
Ardelyx
ARDX
$1.58B
$2.83M 0.72%
+650,000
New +$2.83M
EPZM
37
DELISTED
Epizyme, Inc
EPZM
$2.12M 0.54%
200,000
-75,000
-27% -$795K
TGTX icon
38
TG Therapeutics
TGTX
$5.06B
$1.96M 0.5%
350,000
-275,000
-44% -$1.54M
PLX icon
39
Protalix BioTherapeutics
PLX
$127M
$1.82M 0.46%
250,000
-60,000
-19% -$436K
CMTA
40
DELISTED
Clementia Pharmaceuticals Inc.
CMTA
$1.66M 0.42%
+148,832
New +$1.66M
TCDA
41
DELISTED
Tricida, Inc. Common Stock
TCDA
$1.56M 0.4%
+51,000
New +$1.56M
BFRA
42
DELISTED
Biofrontera AG American Depositary Shares
BFRA
$1.07M 0.27%
79,007
-312,393
-80% -$4.24M
DERM
43
DELISTED
Dermira, Inc.
DERM
$1.06M 0.27%
+97,400
New +$1.06M
ACHN
44
DELISTED
Achillion Pharmaceuticals, Inc.
ACHN
$1.01M 0.26%
+275,000
New +$1.01M
INFI
45
DELISTED
Infinity Pharmaceuticals, Inc.
INFI
$745K 0.19%
+275,000
New +$745K
FOMX
46
DELISTED
Foamix Pharmaceuticals Ltd. Ordinary Shares
FOMX
$521K 0.13%
91,000
-159,000
-64% -$910K
BLRX
47
BioLineRX
BLRX
$15.1M
$267K 0.07%
417
– –
ENTO
48
Entero Therapeutics
ENTO
$4.21M
– –
-1
Closed -$417K
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