OM

Opaleye Management Portfolio holdings

AUM $494M
This Quarter Return
+22.24%
1 Year Return
+68.17%
3 Year Return
+608.37%
5 Year Return
+807.76%
10 Year Return
+24,567.28%
AUM
$386M
AUM Growth
+$386M
Cap. Flow
-$6.89M
Cap. Flow %
-1.78%
Top 10 Hldgs %
62.47%
Holding
49
New
11
Increased
11
Reduced
7
Closed
13

Top Buys

1
PTE
PolarityTE, Inc. Common Stock
PTE
$18.8M
2
AMAG
AMAG Pharmaceuticals, Inc.
AMAG
$8.19M
3
VRDN icon
Viridian Therapeutics
VRDN
$7.69M
4
DNTH icon
Dianthus Therapeutics
DNTH
$7.43M
5
XNCR icon
Xencor
XNCR
$6.66M

Top Sells

1
BPMC
Blueprint Medicines
BPMC
$15.9M
2
AXGN icon
Axogen
AXGN
$13.8M
3
FOMX
Foamix Pharmaceuticals Ltd. Ordinary Shares
FOMX
$10.7M
4
ARDX icon
Ardelyx
ARDX
$5.73M
5
ABLX
Ablynx NV American Depositary Shares
ABLX
$4.91M

Sector Composition

1 Healthcare 97.88%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
APLS icon
26
Apellis Pharmaceuticals
APLS
$3.51B
$5.83M 1.51%
+265,000
New +$5.83M
CMRX
27
DELISTED
Chimerix, Inc.
CMRX
$5.47M 1.42%
1,150,000
+550,000
+92% +$2.62M
AMRN
28
Amarin Corp
AMRN
$311M
$5.41M 1.4%
1,750,000
+5,000
+0.3% +$15.4K
BFRA
29
DELISTED
Biofrontera AG American Depositary Shares
BFRA
$4.76M 1.23%
+391,400
New +$4.76M
FOMX
30
DELISTED
Foamix Pharmaceuticals Ltd. Ordinary Shares
FOMX
$3.83M 0.99%
250,000
-700,000
-74% -$10.7M
EPZM
31
DELISTED
Epizyme, Inc
EPZM
$3.73M 0.96%
275,000
+205,000
+293% +$2.78M
ARQL
32
DELISTED
Arqule Inc
ARQL
$2.32M 0.6%
+420,000
New +$2.32M
PLX icon
33
Protalix BioTherapeutics
PLX
$128M
$1.33M 0.35%
3,100,000
-160,000
-5% -$68.8K
CTIC
34
DELISTED
CTI BioPharma Corp. (DE) Common Stock
CTIC
$803K 0.21%
+161,400
New +$803K
ENTO
35
Entero Therapeutics
ENTO
$4.4M
$417K 0.11%
+130,000
New +$417K
BLRX
36
BioLineRX
BLRX
$15.5M
$222K 0.06%
250,000
– –
ARDX icon
37
Ardelyx
ARDX
$1.57B
– –
-1,135,600
Closed -$5.73M
ASRT icon
38
Assertio
ASRT
$78M
– –
-600,000
Closed -$3.95M
FBIO icon
39
Fortress Biotech
FBIO
$87.8M
– –
-315,000
Closed -$1.43M
QTRX icon
40
Quanterix
QTRX
$202M
– –
-150,000
Closed -$2.56M
SNDX icon
41
Syndax Pharmaceuticals
SNDX
$1.39B
– –
-222,500
Closed -$3.17M
SYRS
42
DELISTED
Syros Pharmaceuticals, Inc. Common Stock
SYRS
– –
-74,074
Closed -$961K
QTNT
43
DELISTED
Quotient Limited Ordinary Shares
QTNT
– –
-60,000
Closed -$282K
ZSAN
44
DELISTED
Zosano Pharma Corporation
ZSAN
– –
-100,000
Closed -$504K
ACHN
45
DELISTED
Achillion Pharmaceuticals, Inc.
ACHN
– –
-1,095,100
Closed -$4.06M
ABLX
46
DELISTED
Ablynx NV American Depositary Shares
ABLX
– –
-90,000
Closed -$4.91M
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