OM

Opaleye Management Portfolio holdings

AUM $494M
This Quarter Return
+23.8%
1 Year Return
+68.17%
3 Year Return
+608.37%
5 Year Return
+807.76%
10 Year Return
+24,567.28%
AUM
$239M
AUM Growth
+$239M
Cap. Flow
+$5.52M
Cap. Flow %
2.31%
Top 10 Hldgs %
60.96%
Holding
53
New
9
Increased
16
Reduced
7
Closed
12

Top Buys

1
CORI
Corium International, Inc.
CORI
$4.13M
2
XLRN
Acceleron Pharma Inc.
XLRN
$3.04M
3
FOMX
Foamix Pharmaceuticals Ltd. Ordinary Shares
FOMX
$2.95M
4
BOLD
Audentes Therapeutics, Inc
BOLD
$2.87M
5
ARDX icon
Ardelyx
ARDX
$2.79M

Top Sells

1
TVRD
Tvardi Therapeutics, Inc. Common Stock
TVRD
$7.08M
2
OCUL icon
Ocular Therapeutix
OCUL
$5.1M
3
SAGE
Sage Therapeutics
SAGE
$3.2M
4
GNMX
Aevi Genomic Medicine, Inc.
GNMX
$1.99M
5
PTLA
Portola Pharmaceuticals, Inc.
PTLA
$1.96M

Sector Composition

1 Healthcare 91.54%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
TTPH
26
DELISTED
Tetraphase Pharmaceuticals, Inc.
TTPH
$2.35M 0.98%
+16,500
New +$2.35M
WVE icon
27
Wave Life Sciences
WVE
$1.27B
$2.33M 0.97%
125,000
+46,700
+60% +$869K
PETX
28
DELISTED
Aratana Therapeutics, Inc.
PETX
$2.28M 0.95%
+350,200
New +$2.28M
XOMA icon
29
Xoma
XOMA
$421M
$2.22M 0.93%
317,200
+276,800
+685% +$1.93M
SYBX icon
30
Synlogic
SYBX
$17.4M
$1.92M 0.8%
+10,934
New +$1.92M
SYRS
31
DELISTED
Syros Pharmaceuticals, Inc. Common Stock
SYRS
$1.76M 0.74%
10,950
+8,435
+335% +$1.36M
ZSAN
32
DELISTED
Zosano Pharma Corporation
ZSAN
$1.73M 0.72%
1,750
-36
-2% -$35.5K
TNXP icon
33
Tonix Pharmaceuticals
TNXP
$243M
– –
0
– -$1.1M
PDSB icon
34
PDS Biotechnology
PDSB
$60.6M
$1.33M 0.56%
6,500
-7,500
-54% -$1.54M
ARQL
35
DELISTED
Arqule Inc
ARQL
$1.2M 0.5%
970,000
+410,000
+73% +$508K
GBT
36
DELISTED
Global Blood Therapeutics, Inc.
GBT
$1.09M 0.46%
+40,000
New +$1.09M
VIRX
37
DELISTED
Viracta Therapeutics, Inc. Common Stock
VIRX
$1.03M 0.43%
10,857
-4,857
-31% -$459K
NEOS
38
DELISTED
Neos Therapeutics, Inc
NEOS
$365K 0.15%
+50,000
New +$365K
BLRX
39
BioLineRX
BLRX
$15.5M
$212K 0.09%
417
– –
GNMX
40
DELISTED
Aevi Genomic Medicine, Inc.
GNMX
– –
-1,070,000
Closed -$1.99M
PTLA
41
DELISTED
Portola Pharmaceuticals, Inc.
PTLA
– –
-50,000
Closed -$1.96M
ALBO
42
DELISTED
Albireo Pharma, Inc. Common Stock
ALBO
– –
-36,500
Closed -$876K
TVRD
43
Tvardi Therapeutics, Inc. Common Stock
TVRD
$270M
– –
-10,694
Closed -$7.08M
SAGE
44
DELISTED
Sage Therapeutics
SAGE
– –
-45,000
Closed -$3.2M
OCUL icon
45
Ocular Therapeutix
OCUL
$2.25B
– –
-550,000
Closed -$5.1M
NGNE icon
46
Neurogene
NGNE
$284M
– –
-4,250
Closed -$1.42M
KPTI icon
47
Karyopharm Therapeutics
KPTI
$61.4M
– –
-4,000
Closed -$770K
IOVA icon
48
Iovance Biotherapeutics
IOVA
$800M
– –
-230,000
Closed -$1.71M
CDTX icon
49
Cidara Therapeutics
CDTX
$1.61B
– –
-6,125
Closed -$955K
ABEO icon
50
Abeona Therapeutics
ABEO
$356M
– –
-11,000
Closed -$1.38M
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