OM

Opaleye Management Portfolio holdings

AUM $494M
This Quarter Return
-24.99%
1 Year Return
+68.17%
3 Year Return
+608.37%
5 Year Return
+807.76%
10 Year Return
+24,567.28%
AUM
$160M
AUM Growth
+$160M
Cap. Flow
-$22.8M
Cap. Flow %
-14.22%
Top 10 Hldgs %
42.9%
Holding
67
New
14
Increased
18
Reduced
12
Closed
15

Top Buys

1
AGIO icon
Agios Pharmaceuticals
AGIO
$4.26M
2
CMRX
Chimerix, Inc.
CMRX
$3.45M
3
TVRD
Tvardi Therapeutics, Inc. Common Stock
TVRD
$2.66M
4
IMMU
Immunomedics Inc
IMMU
$2.59M
5
ADMS
Adamas Pharmaceuticals, Inc.
ADMS
$2.46M

Top Sells

1
RLYP
RELYPSA INC COM
RLYP
$6.24M
2
CEMP
Cempra, Inc.
CEMP
$6.23M
3
SUPN icon
Supernus Pharmaceuticals
SUPN
$4.5M
4
TNXP icon
Tonix Pharmaceuticals
TNXP
$4.33M
5
AVGR
Avinger, Inc. Common Stock
AVGR
$4.32M

Sector Composition

1 Healthcare 77.5%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
AFMD
26
DELISTED
Affimed
AFMD
$2.28M 1.42%
610,000
+15,000
+3% +$56.1K
ZGNX
27
DELISTED
Zogenix, Inc.
ZGNX
$2.22M 1.38%
240,000
+90,000
+60% +$832K
TVTX icon
28
Travere Therapeutics
TVTX
$1.56B
$2.05M 1.28%
150,000
-195,000
-57% -$2.66M
SUPN icon
29
Supernus Pharmaceuticals
SUPN
$2.5B
$1.91M 1.19%
125,000
-295,000
-70% -$4.5M
TRIL
30
DELISTED
Trillium Therapeutics Inc.
TRIL
$1.8M 1.13%
195,000
-15,000
-7% -$139K
PDSB icon
31
PDS Biotechnology
PDSB
$58.3M
$1.69M 1.06%
+185,000
New +$1.69M
CYNA
32
DELISTED
CYNAPSUS THERAPEUTICS INC COM PAR NO PAR (CANADA)
CYNA
$1.44M 0.9%
121,000
+11,000
+10% +$131K
ADAP
33
Adaptimmune Therapeutics
ADAP
$15.3M
$1.43M 0.89%
+175,300
New +$1.43M
CORI
34
DELISTED
Corium International, Inc.
CORI
$1.39M 0.87%
360,000
+5,000
+1% +$19.3K
CYTO
35
DELISTED
Altamira Therapeutics Ltd. Common Shares 0.01 SF (Bermuda)
CYTO
$1.24M 0.77%
340,000
-35,000
-9% -$127K
NBSE
36
DELISTED
NeuBase Therapeutics, Inc. Common Stock
NBSE
$1.18M 0.73%
+366,000
New +$1.18M
XOMA icon
37
Xoma
XOMA
$392M
$1.04M 0.65%
1,350,000
-350,000
-21% -$271K
TENX icon
38
Tenax Therapeutics
TENX
$27.3M
$1.02M 0.64%
499,600
-40,400
-7% -$82.8K
AKAO
39
DELISTED
Achaogen, Inc.
AKAO
$704K 0.44%
+255,000
New +$704K
NKTR icon
40
Nektar Therapeutics
NKTR
$553M
$688K 0.43%
+50,000
New +$688K
MDVN
41
DELISTED
MEDIVATION, INC.
MDVN
$667K 0.42%
+14,500
New +$667K
EVOK icon
42
Evoke Pharma
EVOK
$8.49M
$662K 0.41%
130,000
– –
PRTA icon
43
Prothena Corp
PRTA
$441M
$576K 0.36%
+14,000
New +$576K
NDRM
44
DELISTED
NeuroDerm Ltd. Ordinary Shares
NDRM
$544K 0.34%
+38,500
New +$544K
ALPN
45
DELISTED
Alpine Immune Sciences, Inc. Common Stock
ALPN
$417K 0.26%
+100,000
New +$417K
ACRS icon
46
Aclaris Therapeutics
ACRS
$216M
$341K 0.21%
+18,000
New +$341K
BLRX
47
BioLineRX
BLRX
$16.2M
$255K 0.16%
250,000
– –
CHMA
48
DELISTED
Chiasma, Inc. Common Stock
CHMA
$183K 0.11%
+20,000
New +$183K
AVDL
49
Avadel Pharmaceuticals
AVDL
$1.45B
– –
-250,000
Closed -$3.05M
AXDX
50
DELISTED
Accelerate Diagnostics
AXDX
– –
-75,000
Closed -$1.61M
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